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Composition having preservative efficacy as well as preparation method and application of composition

A composition and efficacy technology, applied in the field of compositions with antiseptic effect, can solve different problems and achieve the effects of mild nature, good bacteriostatic effect, and no toxic and side effects

Inactive Publication Date: 2017-03-22
SHANGHAI CHUNLU BIOCHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there is no scientific conclusion to these debates so far, there are different controversies in the cosmetic industry

Method used

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  • Composition having preservative efficacy as well as preparation method and application of composition
  • Composition having preservative efficacy as well as preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1, a kind of preparation method of the composition with preservative effect is as follows: 0.5 gram carboxymethyl chitosan, 10 grams of 1,2-pentanediol, 10 grams of 1,2-octanediol , 10 grams of 1,2-hexanediol, 1 gram of 1,2-propanediol, 1 gram of 1,3-butanediol, and 1 gram of glycerin are mixed and stirred and dissolved evenly to obtain 33.5 grams of Composition with antiseptic effect.

[0028] Through multiple batches of experiments and clinical verifications on animals, the composition with antiseptic effect described in the present invention has no toxic effect on human body.

[0029] 33.5 grams of the above-prepared composition with antiseptic effect were used for the preservation of cosmetics, wherein the content of the composition with antiseptic effect in the cosmetics was 0.1-5%. That is, 33.5 grams of the composition with antiseptic effect can be used for preservatives with a total weight of 670 grams to 33500 grams. The content of the composition ...

Embodiment 2

[0030] Embodiment 2, a kind of preparation method of the composition with preservative effect is as follows: 10 grams of carboxymethyl chitosan, 80 grams of 1,2-pentanediol, 80 grams of 1,2-octanediol , 80 grams of 1,2-hexanediol, 30 grams of 1,2-propanediol, 30 grams of 1,3-butanediol, and 30 grams of glycerol are mixed and stirred and dissolved evenly to obtain 340 grams of Composition with antiseptic effect.

Embodiment 3

[0031] Embodiment 3, a preparation method of a composition with antiseptic effect is as follows: 5.25 grams of carboxymethyl chitosan, 45 grams of 1,2-pentanediol, 45 grams of 1,2-octanediol 45 grams of 1,2-hexanediol, 15.5 grams of 1,2-propanediol, 15.5 grams of 1,3-butanediol, and 15.5 grams of glycerol are mixed and stirred and dissolved evenly to obtain 186.75 grams of Composition with antiseptic effect.

[0032] 1

2

3

carboxymethyl chitosan

0% 0.15% 0.15% Pentylene glycol

2% 0% 2% Escherichia coli liquid

up to 100% up to 100% up to % Day 1 (colony count cfu / g)

58,000 52,000 52,800 Day 6 (colony count cfu / g)

280,000 9,050 10,000 Day 13 (colony count cfu / g)

incalculable 72,500 100 Day 17 (Colony cfu / g)

incalculable incalculable ＜10

[0033] Table 1

[0034] name English name (English name) content effect EDTA-2Na EDTA-2Na 0.05% Che...

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Abstract

The invention discloses a composition having a preservative efficacy as well as a preparation method and an application of the composition. The composition having the preservative efficacy consists of 0.5-10 parts by weight of carboxymethyl chitosan, 10-80 parts by weight of 1,2-pentanediol, 10-80 parts by weight of 1,2-octanediol, 10-80 parts by weight of 1,2-hexanediol, 1-30 parts by weight of 1,2-propanediol, 1-30 parts by weight of 1,3-butanediol and 1-30 parts by weight of propanetriol. According to the preparation method of the composition having the preservative efficacy, the composition is prepared by mixing the materials in accordance with the parts by weight, and uniformly stirring and dissolving an obtained mixture. The composition having the preservative efficacy can take a preservative effect in cosmetics, wherein the content of the composition having the preservative efficacy in the cosmetics is 0.1-5%. The composition having the preservative efficacy is free from any banned and restricted preservative components, and the composition can take a relatively ideal antibacterial effect and broad-spectrum antibacterial and preservative capacities on bacteria and fungi.

Description

technical field [0001] The invention relates to the technical field of cosmetic additives, in particular to a composition with antiseptic effect which does not contain formaldehyde releasing body and strong reducing agent. Background technique [0002] Cosmetics are rich in nutrients, which are especially suitable for the growth of microorganisms, so preservatives need to be added to cosmetics. The purpose of including preservatives in cosmetics is to inhibit the growth and generation of microorganisms, avoid deterioration of cosmetics and maintain freshness and durability. sex. [0003] At present, almost every common antiseptic active ingredient in the market basically has formaldehyde or formaldehyde-releasing body. The potential carcinogenicity of formaldehyde and formaldehyde-releasing bodies, and the potential allergenicity of organic halogen compounds have been discussed by everyone. In the past two years, the association between paraben and hormone secretion and so...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/34A61Q19/00
CPCA61K8/736A61K8/345A61K2800/10A61K2800/524A61Q19/00
Inventor 徐宇帆
Owner SHANGHAI CHUNLU BIOCHEM CO LTD
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