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Method for measuring thickness of capsule housing based on terahertz time domain spectrum technology

A terahertz time-domain and spectroscopic technology is applied in the field of measuring the thickness of the capsule shell based on the terahertz time-domain spectroscopic technology, which can solve the problems of low measurement accuracy, easy to be disturbed by external vibration, unstable measurement state, etc. The effect of high precision, stable measurement state, and not easy to interfere

Inactive Publication Date: 2017-03-08
SHANDONG ACAD OF SCI INST OF AUTOMATION
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Problems solved by technology

[0003] At present, the quality test of the capsule shell is mostly completed by contact measurement, but there are many problems in the contact measurement process, such as: low measurement accuracy, unstable measurement state, easy to be disturbed by external vibration, and more importantly, it cannot Meet the detection needs of the automatic capsule production line

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  • Method for measuring thickness of capsule housing based on terahertz time domain spectrum technology
  • Method for measuring thickness of capsule housing based on terahertz time domain spectrum technology
  • Method for measuring thickness of capsule housing based on terahertz time domain spectrum technology

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Embodiment Construction

[0027] The present invention is described in detail below in conjunction with accompanying drawing:

[0028] What the experiment of the present invention adopts is the time-domain spectroscopy system FiCO of American Zomega Company, such as figure 2 As shown, the methods for generating and detecting THz are photoconductive antenna and electro-optic sampling, respectively. The frequency range of the terahertz pulse is 0.1-2THz, and the system is mainly composed of a femtosecond laser, a time delay system, a terahertz transmitter (photoconductive antenna) and a terahertz receiver (electro-optic crystal).

[0029] The femtosecond laser emitted by the femtosecond laser is divided into two beams through the beam splitter. One beam of laser light enters the parabolic mirror after passing through the photoconductive antenna. Enter the plane mirror behind the stage, enter the other parabolic mirror under the refraction of the plane mirror, and then pass through high-resistance silic...

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Abstract

The invention discloses a method for measuring thickness of a capsule housing based on terahertz time domain spectrum technology. The method comprises the following steps of establishing a capsule housing thickness measuring model; on the condition that refractive index of the to-be-measured capsule housing is known, preventing testing for the refractive index of the to-be-measured capsule housing, and otherwise, testing the refractive index of the to-be-measured capsule housing; measuring a delay time difference deltat between an upper-surface reflection peak and a lower-surface reflection peak of the to-be-measured capsule housing; and calculating the thickness of the to-be-measured capsule housing according to an established capsule housing thickness measuring model d=c*deltat / 2n. The method of the invention realizes high-precision testing for the thickness of the capsule housing without damage of the capsule housing or contact with the capsule housing. The method supplies technical supports for online monitoring and management for quality of the capsule housing and better serves a medicine quality inspection industry.

Description

technical field [0001] The invention relates to the field of medicine quality detection, in particular to a method for measuring the thickness of a capsule shell based on terahertz time-domain spectroscopy. Background technique [0002] The emergence of capsules solves the problem of poor taste when people take medicine, while ensuring good absorption effect. Different diseases require that the release position of the drug effect is different in the human body, and at the same time, there are certain requirements for the release speed of the drug effect. When the thickness of the capsule shell is small, the drug is released too quickly and cannot be fully absorbed by the human body; when the thickness of the capsule shell is large, the human body will not fully absorb the drug and will be excreted. During the production process of the capsule shell, the thickness of the capsule shell needs to be inspected at a certain frequency. [0003] At present, the quality test of the...

Claims

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Application Information

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IPC IPC(8): G01B11/06
CPCG01B11/06
Inventor 杨传法刘陵玉常天英崔洪亮张献生孙中琳王忠民张延波
Owner SHANDONG ACAD OF SCI INST OF AUTOMATION
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