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A traditional Chinese medicine prescription for treating diseases related to low estrogen secretion level

A technology of estrogen and traditional Chinese medicine, applied in endocrine system diseases, medical formulas, drug combinations, etc., can solve the problems of increasing the risk of breast cancer and stroke, which cannot be completely eliminated, and achieve the improvement of emotional abnormalities, simple composition, and increased E2 content Effect

Active Publication Date: 2020-05-05
DIAOYUTAI MEDICAL GRP JILIN TIANQIANG PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this regard, estrogen replacement therapy (ERT) is currently the only clinical treatment for low estrogen, but long-term use of estrogen increases the risk of breast cancer, endometrial cancer and stroke, and even combined with progesterone cannot completely eliminate this danger

Method used

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  • A traditional Chinese medicine prescription for treating diseases related to low estrogen secretion level
  • A traditional Chinese medicine prescription for treating diseases related to low estrogen secretion level
  • A traditional Chinese medicine prescription for treating diseases related to low estrogen secretion level

Examples

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Effect test

Embodiment 1

[0027] Embodiment 1, Chinese medicine prescription and its preparation and pharmacodynamics experiment

[0028] The preparation method of the traditional Chinese medicine prescription:

[0029] 1. Preparation of Acanthopanax senticosus: take the Acanthopanax senticosus medicinal material, grind it into a coarse powder, pass through a 40-mesh sieve, add 60% ethanol to 10 times the amount of reflux extraction, and extract twice for 1 hour each time. Concentrated Acanthopanax concentrated solution 1500mL, extracted with water-saturated n-butanol 4 times 1500mL each time, combined n-butanol extract, dried under reduced pressure at 60°C, crushed to obtain powder.

[0030] 2. Preparation of Cimicifuga: take Cimicifuga medicinal material, grind it into coarse powder, pass through a 40-mesh sieve, add 70% ethanol to reflux and extract twice for 1 hour each time, discard the residue, concentrate the ethanol extract to dryness, and pulverize to obtain a powder.

[0031] 3. Mix the extr...

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Abstract

The invention discloses a traditional Chinese medicines formula for treating related diseases with low estrogen secretion level. The active components are made of acanthopanax and rhizoma cimicifugae at ratio of 1: 0.1-1 by mass. The traditional Chinese medicines formula has simple compatible composition of acanthopanax and rhizoma cimicifugae, and wide drug source; the drug action is clear; the drug effect after adding acanthopanax and rhizoma cimicifugae is obviously increased; the traditional Chinese medicines formula is applicable to treat low estrogen secretion level caused by woman perimenopause, premature ovarian failure, oophorectomy and others, and improve hectic fever, palpitation, anxiety, depression, restless, irritability, fatigue, pain in back and loin, and other symptoms.

Description

technical field [0001] The invention relates to a traditional Chinese medicine prescription for treating diseases related to low estrogen secretion level. Background technique [0002] Low estrogen levels are a common disease in gynecology. Perimenopausal syndrome is the most common one, and 90% of women may experience symptoms ranging from mild to severe. Before and after menopause, the disease is due to the decline of ovarian function and the decrease of estrogen level in the body, which leads to the dysfunction of the neuroendocrine system, which causes the dysfunction of the hypothalamus-pituitary-ovary axis, and the main symptoms are autonomic dysfunction, accompanied by mental and psychological disorders. A group of clinical syndromes of symptoms. In addition, due to surgery, tumor treatment, and various reasons, ovarian function decline, amenorrhea, and dysmenorrhea before the age of 40 are often accompanied by decreased estrogen levels, which have become factors th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P5/30A61P5/12
CPCA61K36/254A61K36/71A61K2300/00
Inventor 孙明杰黄颖杨威周艳华崔海峰冯淑怡孙丽华石晓路武乾
Owner DIAOYUTAI MEDICAL GRP JILIN TIANQIANG PHARMA
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