AIDS biotherapy reactor

A biological treatment and reactor technology, applied in the direction of drug devices, other medical devices, suction devices, etc., to achieve the effect of high cost and large side effects of drugs

Active Publication Date: 2017-01-04
浙江同创医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the preparation of CD4+ T cells for the treatment of AIDS in vitro

Method used

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Embodiment Construction

[0010] figure 1 It is an application schematic diagram of the AIDS biotherapy reactor proposed according to the present invention.

[0011] figure 2 It is a schematic diagram of the internal structure of the plasma separator proposed according to the present invention.

[0012] image 3 It is a schematic diagram of the internal structure of the AIDS biotherapy reactor proposed according to the present invention.

[0013] figure 1 Among them, one end of the arterial blood line tube (1) is connected with the arterial blood vessel, and the other end is connected with the plasma separator (4) through the heparin pump (2) and the blood pump (3), and the plasma separator (4) is connected through the plasma pump (6) ) and circulation pipeline (7) are connected with two parallel reactors (8), reactor (9), and then connected with circulation pipeline (10), vein pipeline (5) successively, vein pipeline (5) The other end is connected to the vein.

[0014] figure 2 Among them, 1 ...

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Abstract

The invention relates to an AIDS biotherapy reactor, and belongs to the field of bio-medicine. The AIDS biotherapy reactor is characterized in that by changing the genetic structures of T cells through exogenous gene integration, an immortal cell line is prepared and CD4+ cells, which can bond HIV and can generate cell factors, are prepared by taking T cell surface antibodies as cell growth activators through artificial industry, and the immortal cell line is covered by virtue of a high-biocompatibility material, so that the reactor is prepared, wherein the reactor not only can prevent the filtration-out of the cells and debris thereof and even the HIV but also can offer a place to the CD4+ cells to generate the cell factors and to bond the HIV; when plasma, which is isolated in vitro, passes through the reactor, the HIV, which is bonded with the CD4+ cells or enter the cells, is scavenged, and meanwhile, the generated cell factors, along with the plasma, flow out from intercellular spaces and then return into a body, so that an artificial CD4+T cell substitutive therapy by which the HIV is introduced out of the body and is scavenged and the cell factors are supplemented is achieved; and the substitutive therapy, in comparison with a conventional therapy which is limited in killing the HIV in vivo but is difficult to implement, is more feasible and is free from toxic and side effects.

Description

technical field [0001] The invention relates to an AIDS biological treatment reactor in the field of biomedicine, which is mainly used for removing HIV dissociated outside the blood cells of AIDS patients in vitro, and at the same time replenishing CD4+T cell factors lacking in the body of AIDS patients to achieve the purpose of treating AIDS. Background technique [0002] AIDS is an infectious disease caused by human immunodeficiency virus (Human Immunodeficiency Virus, HIV). So far, 208 countries and regions in the world have been seriously threatened by AIDS. About 40 million people have been infected with AIDS, and the death toll has exceeded 20 million. About 6,000 people become AIDS-infected people every day, and more than 300 people die every day. on AIDS. HIV-infected people in China are in a period of rapid growth, and the number has far exceeded 1 million at present. AIDS has become another major infectious disease facing mankind after tumors, cardiovascular and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/36
CPCA61M1/3627A61M2202/0415A61M2202/206A61M2205/33A61M2205/7509A61M1/3601A61M1/3612A61M1/362A61M2202/0021A61M2202/0064
Inventor 翁炳焕李兰娟徐威许亚丽虞晓鹏
Owner 浙江同创医疗科技有限公司
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