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Regulating device for simulating rat body fluid distribution in weightless state

An adjustment device and a technology for simulating weightlessness, which is applied in the field of aviation biomedical engineering, can solve problems such as the inability to study the influence of a single factor, and achieve the effects of improving research accuracy, simple operation, and avoiding trauma

Inactive Publication Date: 2016-12-14
BEIHANG UNIV
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Problems solved by technology

[0003] The tail-suspended rat model has some shortcomings in the research. This model can only study the influence of two factors on bone loss at the same time, and cannot study the influence of a single factor, which makes the research on the mechanism of weightlessness bone loss have certain limitations.

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  • Regulating device for simulating rat body fluid distribution in weightless state
  • Regulating device for simulating rat body fluid distribution in weightless state

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Embodiment Construction

[0018] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0019] The invention provides a device for adjusting the body fluid distribution of rats under simulated weightlessness, the device is as follows: figure 1 As shown, it includes a lower limb position adjustment control unit 101 , a diet activity platform 102 , a beam 103 , a boom 104 , a box body 105 and a drinking bottle 106 . Described casing 105 is rat cage structure, and described drinking water bottle 106 is arranged on the outer wall of described casing 105, enters on described eating and drinking activity platform 102 through the aperture on casing 105, provides drinking water to rat . The eating and drinking activity platform 102 is fixed in the box body 105 with a height of one-third of the box body 105, and is used to provide diet and drinking water and necessary activities for the rats. The top wall of the box body 105 is provided with tw...

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Abstract

The invention discloses a regulating device for simulating rat body fluid distribution in a weightless state, and belongs to the technical field of aviation biomedical engineering. The regulating device comprises a lower limb body position regulating control unit, a diet activity platform, a beam, a hanging rod, a tank and a drinking water bottle, wherein the tank is of a rat cage, the drinking water bottle is arranged on the outer side wall of the tank, and the diet activity platform is fixed into the tank. Two parallel rails are arranged on the top wall of the tank, the beam is hung below the rails, the hanging rod is hung below the beam, two ropes are hung on the hanging rod, and the other ends of the ropes are hung on the lower limb body position regulating control unit. The rear limb hanging weightless state and free diet of rats are ensured, blood supply can be changed by regulating rear limb body positions of the rats, and an excellent model method is provided for researching the influence of blood on weightless bone loss. The method used by the device is simple to operate, the rats cannot be wounded, and long-term experiments can be performed.

Description

technical field [0001] The invention belongs to the technical field of aeronautical biomedical engineering, and in particular relates to an adjusting device for rat body fluid distribution in a simulated weightlessness state, capable of regulating the blood supply of the rear limbs of rats in a simulated weightlessness state. Background technique [0002] Bone loss caused by a weightless environment is one of the main problems affecting astronauts' space exploration. The animal model for simulating a weightless environment often adopts the rat tail-suspension model proposed by Morey-Holton. Directional distribution is the two main factors affecting weightlessness bone loss. [0003] The tail-suspended rat model has some shortcomings in the research. This model can only study the influence of two factors on bone loss at the same time, and cannot study the influence of a single factor, which makes the research on the mechanism of weightlessness bone loss have certain limitatio...

Claims

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Application Information

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IPC IPC(8): A01K1/03A01K5/00A01K7/00A01K15/04
CPCA01K1/031A01K5/00A01K7/00A01K15/04
Inventor 孙联文王守辉王敏樊瑜波
Owner BEIHANG UNIV
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