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Traditional Chinese medicine composition for treating lung cancer solid tumor

A solid tumor and composition technology, which is applied in the direction of drug combination, antineoplastic drugs, and pharmaceutical formulations, can solve the problems of poor sensitivity and achieve the effects of simple preparation, good therapeutic effect, and easy availability of raw materials

Inactive Publication Date: 2016-12-07
TIANJIN HESHENG MEDICAL TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, the treatment of lung cancer solid tumors mainly includes surgical treatment, radiotherapy, chemotherapy, traditional Chinese medicine treatment and new treatment methods represented by molecular targeted therapy. However, lung cancer solid tumors are poorly sensitive to chemotherapy and radiotherapy. Therapeutic method is an urgent problem to be solved in the treatment of solid tumors of lung cancer

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] 110 parts of Rehmannia, 10 parts of Phellodendron, 10 parts of Gardenia, 13 parts of Scutellaria, 4 parts of Aloe Vera, 4 parts of Qingdai, 4 parts of Rhubarb, 8 parts of Woody Fragrance, 4 parts of Phellodendron, 4 parts of Dangshenlong, 4 parts of Radix Paeoniae Rubra, Yuanshen 3 parts, 2 parts of Northern Radix Ginseng, 2 parts of Ophiopogon japonicus, 4 parts of Anemarrhena, 4 parts of Dendrobium, 2 parts of fresh black skin, and 2 parts of fresh hundred.

[0014] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 60 minutes, decoct twice for 3 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 Extraction, the relative density is the test result at 60 degrees Celsius, add ethanol to alcohol content of 75% (v / v), let it stand for 24 hours, take the supernatant, reclaim the ethanol concentra...

Embodiment 2

[0016] 130 parts of Rehmannia, 15 parts of Phellodendron, 15 parts of Gardenia, 18 parts of Scutellaria, 6 parts of Aloe Vera, 6 parts of Qingdai, 6 parts of Rhubarb, 10 parts of Woody Fragrance, 6 parts of Phellodendron, 6 parts of Dangshenlong, 6 parts of Radix Paeoniae Rubra, Yuanshen 5 parts, 4 parts of Northern Radix Ginseng, 4 parts of Ophiopogon japonicus, 4-6 parts of Anemarrhena, 6 parts of Dendrobium, 3 parts of fresh black skin, and 4 parts of fresh hundred.

[0017] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 60 minutes, decoct twice for 3 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 Extraction, the relative density is the test result at 60 degrees Celsius, add ethanol to alcohol content of 75% (v / v), let it stand for 24 hours, take the supernatant, reclaim the ethanol concen...

Embodiment 3

[0019] 120 parts of Rehmannia, 13 parts of Phellodendron, 13 parts of Gardenia, 15 parts of Scutellaria, 5 parts of Aloe, 5 parts of Qingdai, 5 parts of Rhubarb, 9 parts of Woody Fragrance, 5 parts of Phellodendron, 5 parts of Dangshenlong, 5 parts of Radix Paeoniae Rubra, Yuanshen 4 parts, 3 parts of Northern Radix Ginseng, 3 parts of Ophiopogon japonicus, 45 parts of Anemarrhena, 5 parts of Dendrobium, 3 parts of fresh black skin, and 3 parts of fresh Baibu.

[0020] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 60 minutes, decoct twice for 3 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 Extraction, the relative density is the test result at 60 degrees Celsius, add ethanol to alcohol content of 75% (v / v), let it stand for 24 hours, take the supernatant, reclaim the ethanol concentration, ...

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Abstract

The invention provides a traditional Chinese medicine composition for treating a lung cancer solid tumor. The traditional Chinese medicine composition is prepared from the following ingredients in parts by weight: 100 to 150 parts of radix rehmanniae, 10 to 15 parts of cortex phellodendri, 10 to 20 parts of fructus gardeniae, 10 to 20 parts of radix scutellariae, 3 to 8 parts of aloes, 3 to 8 parts of indigo naturalis, 3 to 8 parts of radix et rhizoma rhei, 7 to 12 parts of radix aucklandiae, 3 to 8 parts of cortex phellodendri, 3 to 8 parts of Dang sen long, 2 to 6 parts of radix paeoniae rubra, 1 to 5 parts of radix scrophulariae, 2 to 6 parts of radix glehniae, 1 to 5 parts of dwarf lilyturf roots, 3 to 8 parts of rhizoma anemarrhenae, 3 to 8 parts of herba dendrobii, 1 to 4 parts of fresh polyalthia nemoralis roots and 1 to 5 parts of fresh radix stemonae. Experiment results show that the traditional Chinese medicine composition has a good treatment effect in the aspect of inhibiting the lung cancer solid tumor. The traditional Chinese medicine composition can be used as lung-cancer-resistant medicine. Compared with the prior art, the traditional Chinese medicine composition has the advantages that the anti-cancer activity is high; in addition, the traditional Chinese medicine composition can be used as the anti-cancer medicine; in addition, the preparation of the traditional Chinese medicine composition is simple; the traditional Chinese medicine composition is basically non-toxic; the raw materials can be easily obtained; the traditional Chinese medicine composition is suitable for being used by wide people; good application prospects are realized.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating solid tumors of lung cancer. technical background [0002] Lung cancer is the most common malignant tumor in middle-aged and elderly people, and its incidence is on the rise worldwide. Lung cancer is the cancer with the highest incidence rate in my country, with about 400,000 new cases every year. The World Health Organization predicts that if smoking and air pollution are not controlled, by 2025, my country will have more than 1 million new cases of lung cancer, becoming the world's largest lung cancer country. [0003] Lung cancer solid tumor is the most common pathological type of lung cancer, accounting for about 85% of lung cancer. Lung cancer solid tumors include squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Cancer cells in lung cancer solid tumors grow slowly, have a relatively low degree of malignancy, and spread and metastasize later. Clini...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P35/00
Inventor 田东奎何磊
Owner TIANJIN HESHENG MEDICAL TECH DEV
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