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Noon tea granules and preparation method and application thereof

A technology of afternoon tea and granules, which is applied in the direction of making medicines into special physical or ingestible devices, pharmaceutical formulas, medical preparations containing active ingredients, etc., which can solve the problems of low content of active ingredients, affecting clinical applications, and patients. Large dosage and other problems, to achieve good practicability, solve the effect of low drying efficiency and improve drying efficiency

Inactive Publication Date: 2016-11-16
NANJING ZHENGKUAN MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The extraction method of tea granules in the prior art at noon has a rough and backward process, many impurities, and low content of active ingredients, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the clinical application of this product

Method used

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  • Noon tea granules and preparation method and application thereof
  • Noon tea granules and preparation method and application thereof
  • Noon tea granules and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Take 50g of Cangzhu, 50g of Bupleurum, 50g of Notopterygium, 50g of Fangfeng, 50g of Angelica dahurica, 50g of Chuanxiong, 50g of Patchouli, 50g of Peucedanum, 50g of Forsythia, 50g of Tangerine Peel, 50g of Hawthorn, 50g of Citrus aurantium, 75g of fried malt, 50g of Licorice, 75g bellflower, 50g Liuchao Shenqu, 75g perilla leaves, 75g magnolia bark, 1600g black tea, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, filter, add medicinal residues and 8 times the weight of medicinal materials in water, Decoct for 1 hour, filter out the medicinal liquid, combine the two decoction liquids, concentrate to a relative density of 1.05 at 60°C, add ethanol to make the volume percentage of the alcohol content reach 75%, stir, stand still, filter, and concentrate the filtrate to 65 The relative density at ℃ is 1.25, and the ethanol is recovered to obtain a concentrated solution, and supercritical extraction is used to obtain a supercritica...

Embodiment 2

[0029] Take 50g of Cangzhu, 50g of Bupleurum, 50g of Notopterygium, 50g of Fangfeng, 50g of Angelica dahurica, 50g of Chuanxiong, 50g of Patchouli, 50g of Peucedanum, 50g of Forsythia, 50g of Tangerine Peel, 50g of Hawthorn, 50g of Citrus aurantium, 75g of fried malt, 50g of Licorice, 75g bellflower, 50g Liuchao Shenqu, 75g perilla leaves, 75g magnolia bark, 1600g black tea, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, filter, add medicinal residues and 8 times the weight of medicinal materials in water, Decoct for 1 hour, filter out the medicinal liquid, combine the two decoction liquids, concentrate to a relative density of 1.05 at 60°C, add ethanol to make the volume percentage of the alcohol content reach 75%, stir, stand still, filter, and concentrate the filtrate to 65 The relative density at ℃ is 1.25, and the ethanol is recovered to obtain a concentrated solution, and supercritical extraction is used to obtain a supercritica...

Embodiment 3

[0033] Take 50g of Cangzhu, 50g of Bupleurum, 50g of Notopterygium, 50g of Fangfeng, 50g of Angelica dahurica, 50g of Chuanxiong, 50g of Patchouli, 50g of Peucedanum, 50g of Forsythia, 50g of Tangerine Peel, 50g of Hawthorn, 50g of Citrus aurantium, 75g of fried malt, 50g of Licorice, 75g bellflower, 50g Liuchao Shenqu, 75g perilla leaves, 75g magnolia bark, 1600g black tea, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, filter, add medicinal residues and 8 times the weight of medicinal materials in water, Decoct for 1 hour, filter out the medicinal liquid, combine the two decoction liquids, concentrate to a relative density of 1.05 at 60°C, add ethanol to make the volume percentage of the alcohol content reach 75%, stir, stand still, filter, and concentrate the filtrate to 65 The relative density at ℃ is 1.25, and the ethanol is recovered to obtain a concentrated solution, and supercritical extraction is used to obtain a supercritica...

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Abstract

The invention provides noon tea granules. The noon tea granules are prepared through the steps that 50 g of rhizoma atractylodis, 50 g of radix bupleuri, 50 g of notopterygium roots, 50 g of radix saposhnikoviae, 50 g of radix angelicae, 50 g of rhizoma chuanxiong, 50 g of herba pogostemonis, 50 g of radix peucedani, 50 g of fructus forsythiae, 50 g of pericarpium citri reticulatae, 50 g of fructus crataegi, 50 g of fructus aurantii immaturus, 75 g of roasted malt, 50 g of licorice roots, 75 g of radix platycodonis, 50 g of stir-fried medicated leaven, 75 g of folium perillae, 75 g of cortex magnoliae officinalis and 1,600 g of black tea are taken, water extraction and alcohol precipitation are conducted to obtain a concentrated solution, supercritical extraction is conducted to obtain a supercritical extract, and the noon tea granules are prepared through a conventional method. The prepared noon tea granules are high in platycodin D content, and application of the noon tea granules in preparation of drugs for inhibiting rat adrenal pheochromocytoma PC-12 cell proliferation is found.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extraction, in particular to Wushicha granules, a preparation method and application thereof. Background technique [0002] The prior art method for extracting tea granules at noon has a rough and backward process, many impurities, and low content of active ingredients, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the clinical application of this product. Contents of the invention [0003] Purpose of the invention: In order to solve the above problems, the purpose of the present invention is to provide a kind of afternoon tea granule and its preparation method and application. [0004] Technical scheme: the purpose of the present invention is achieved by the following scheme: [0005] A Wushi tea granule, the preparation method is: take 50g of Atractylodes atractylodes, 50g of Bupleurum, 50g of Notopterygium, 50g of Fangf...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61K9/16A61P35/00A61J3/00
CPCA61J3/00A61K9/1605A61K36/00A61K36/23A61K36/232A61K36/233A61K36/236A61K36/237A61K36/238A61K36/284A61K36/346A61K36/484A61K36/53A61K36/535A61K36/575A61K36/634A61K36/734A61K36/752A61K36/82A61K36/899A61K36/8998A61K2236/37A61K2300/00
Inventor 卞毓平
Owner NANJING ZHENGKUAN MEDICAL TECH
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