Customizable multi-dimensional high-density flexible brain electrode and manufacturing method thereof

Abstract

The invention provides a customizable multi-dimensional high-density flexible brain electrode and a manufacturing method thereof. The manufacturing method at least includes the steps that a contact biological electrode is prepared; a micro-needle biological electrode is prepared; the micro-needle biological electrode and the contact biological electrode are combined to form the multi-dimensional composite brain electrode. Non-degradable type flexible thin films in the contact biological electrode serve as an electrode supporting layer and an isolation layer to manufacture a customizable cerebral cortex contact biological electrode with high density and high attachment; degradable flexible thin films in the micro-needle biological electrode serve as a micro-needle and a substrate material, the micro-needle and the substrate material are integrated to be combined into a multi-dimensional composite biological electrode. According to the brain electrode, the sampling space resolution of brain electrical signals is high, the sampling result is precise, damage to living bodies is small, and a great breakthrough can be brought to brain function detection and research.

Description

Technical field [0001] The invention belongs to the field of brain function detection, and relates to a brain electrode and a manufacturing method thereof, in particular to a customizable multi-dimensional high-density flexible brain electrode and a manufacturing method thereof. Background technique [0002] EEG monitoring has always played an irreplaceable role in the diagnosis and surgical positioning of epilepsy. In recent years, with the launch of the "Brain Project" worldwide, high-quality EEG signal collection has become increasingly important and will directly help Decoding the brain function, promote a series of high-tech development based on this, such as: brain-computer interface, neuroregulation, etc. The methods for collecting EEG signals mainly rely on brain electrodes. Currently, there are four widely used brain electrodes: 1) Scalp EEG (EEG); 2) Cortical EEG (EcoG); 3) Cortical Microelectrode (Microelectrode) ); 4) Deep brain electrodes (SEEG). These four electro...

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Problems solved by technology

[0004] In view of the shortcomings of the prior art described above, the purpose of the present invention is to provide a customizable multi-dimensional high-density flexible brain electrode and its manufacturing method, which are used to solve the problem of hard texture, poor conformability, and poor conformability of the brain electrodes in the prior art. Problems such as low density and inaccurate acquisition signals

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