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Application of forsythin derivatives in preparation of drugs for preventing or/and treating liver damage

A drug, the technology of forsythiatin, applied in the field of medicine, can solve problems such as allergic reactions and immunogenicity

Active Publication Date: 2019-07-30
富力
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, at this stage, the serine protease inhibitors used clinically in my country are bovine lung extracts, which will produce immunogenicity as heterologous proteins, especially when used in large quantities in clinical practice, allergic reactions will occur

Method used

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  • Application of forsythin derivatives in preparation of drugs for preventing or/and treating liver damage
  • Application of forsythin derivatives in preparation of drugs for preventing or/and treating liver damage
  • Application of forsythin derivatives in preparation of drugs for preventing or/and treating liver damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Embodiment 1 forsythin tablet

[0057] 1. Prepare raw materials according to the following ratio

[0058]

[0059]

[0060] 2. Mix forsythin and starch evenly, make granules, add talcum powder and magnesium stearate, mix evenly, and press into 10,000 tablets.

Embodiment 2

[0061] Embodiment 2 forsythin capsules

[0062] 1. Prepare raw materials according to the following ratio

[0063] Forsythin (purity 60%) 200g

[0064] Starch 1000g

[0065] 2. Mix forsythin and starch evenly and pack into capsules to make 10,000 capsules.

Embodiment 3

[0066] Embodiment 3 forsythin capsules

[0067] 1. Prepare raw materials according to the following ratio

[0068] Forsythin (purity 98%) 500g

[0069] Starch 1000g

[0070] 2. Mix forsythin and starch evenly and pack into capsules to make 10,000 capsules.

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Abstract

An application of forsythin, a forsythin derivative, and a composition of forsythin and forsythin lignans in preparing a medicine or health care product for protecting the liver, preventing liver injury, and a medicine or health care product for preventing and / or treating liver injury, wherein the medicine or the health care product comprises the forsythin, the forsythin derivative, or the composition of forsythin and the forsythin lignans.

Description

technical field [0001] The invention relates to the field of medicine, and relates to a drug for protecting the liver and resisting liver damage, in particular to an application of traditional Chinese medicine forsythia and forsythia leaf extract components in the drug for protecting the liver and resisting liver damage. Background technique [0002] The liver is the largest metabolic organ and digestive gland in the body. Almost all substances absorbed from the gastrointestinal tract enter the liver, where they are synthesized, decomposed, transformed, and stored. The liver is also an important immune organ of the body. Various harmful factors and substances, such as viruses, poisons, drugs, ethanol, hypoxia, immunity, etc., can act on liver tissue, which can directly cause damage to liver cells to varying degrees, and can also cause liver cell damage through the activation of cytokine networks. Injury, regeneration, liver fibrosis, and advanced liver failure. The researc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K36/258A61K36/9066A61K36/484A61K36/489A61K36/282A61K36/71A61K36/65A61K36/232A61K36/481A61P1/16A23L33/10A61K31/34A61K31/375A61K31/355
CPCA61K31/7048A61K36/9066
Inventor 付强富力王凯乾惠敏冯雪鲁明明盖鑫刘正贤
Owner 富力
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