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Compound skin cream for treating leucoderma and preparation method thereof

An ointment and a vitiligo technology are applied to the compound skin ointment for treating vitiligo and the field of preparation thereof, which can solve the problems of patient pain, large toxic and side effects, and high recurrence rate, and achieve the effects of alleviating pain and improving the therapeutic effect.

Inactive Publication Date: 2016-10-12
CHINESE PEOPLES LIBERATION ARMY AIR FORCE GENERAL HOSPITAL
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

Although most of the treatment methods can improve the state of the disease to a certain extent, once the treatment is stopped, the recurrence rate is high, and the treatment process makes the patient more painful, and taking some drugs has relatively large toxic and side effects, which will have a negative impact on the patient's health. affected by

Method used

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  • Compound skin cream for treating leucoderma and preparation method thereof
  • Compound skin cream for treating leucoderma and preparation method thereof
  • Compound skin cream for treating leucoderma and preparation method thereof

Examples

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Embodiment 1

[0028] Example 1: A preparation method for a compound skin cream for treating vitiligo, comprising the steps of:

[0029] (1), preparation of psoralen extract: take psoralen extract of 30g by weight, add 50% ethanol to soak for 2h, then reflux extraction twice, add 8 times the amount of solvent for the first time, reflux for 1.5h, the second time Add 6 times the amount of solvent, decoct for 1 hour, filter the extract, combine the filtrate, recover the ethanol until it has no alcohol smell, let it stand overnight, pour off the supernatant, and get a brown-black viscous substance, add an appropriate amount of methanol to dissolve, add a little activated carbon , refluxed for 10min, filtered while hot, recovered methanol to a small volume from the filtrate, and placed it for crystallization. Cold crystallization, filter to remove crystals, rinse with a small amount of methanol, and dry below 80°C to obtain psoralen extract.

[0030] (2), preparation of Baizhi extract: take by...

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Abstract

The invention discloses compound skin cream for treating leucoderma and a preparation method thereof, and belongs to the technical field of external-use traditional Chinese medicine. The cream is prepared through the method comprising the steps that 1, fructus psoraleae extract and radix angelicae dahuricae extract are prepared; 2, oil-phase raw materials are prepared; 3, water-phase raw materials are prepared; 4, the oil-phase raw materials and the water-phase raw materials are heated, stirred and then emulsified; 5, the temperature a main pot is reduced to 62 DEG C, the fructus psoraleae extract and the radix angelicae dahuricae extract which are prepared in the step 1 are added for emulsification, and high-pressure homogenizinng is carried out for several circles; 6, after cooling, garland flower essence is added, discharging is carried out when the temperature is reduced to 37 DEG C, and the cream is obtained. The compound skin cream and the preparation method thereof have the advantages that the compound skin cream is directly applied to an affected part, and the pain of a patient during treatment is relieved; the fructus psoraleae extract and the radix angelicae dahuricae extract with the effects of stimulating and activating the activity of tyrosinase, stimulating melanocytes and enhancing the melanin synthesizing capacity are adopted, and therefore the compound preparation has a good treatment effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine for external use, and in particular relates to a compound skin cream for treating vitiligo and a preparation method thereof. Background technique [0002] Vitiligo is a common acquired localized or generalized skin depigmentation disease. Caused by the loss of skin melanocyte function, the etiology is unknown, and it may be related to genetics, autoimmunity, self-destruction of melanocytes, lack of trace elements, and psychoneurochemical factors. Vitiligo can occur at all ages. Although vitiligo does not affect health, when it occurs on exposed parts such as the face and neck, it will seriously affect the appearance and easily cause mental or psychological pain to patients. Because the cause of the disease is not clear, easy to diagnose and difficult to treat, it is a major difficult disease in the field of dermatology today. [0003] Today, the main methods of treating viti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/487A61K9/06A61K47/46A61P17/00
CPCA61K36/487A61K9/0014A61K9/06A61K36/232A61K47/46A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 蔡瑞康袁海龙吴燕沈成英徐荣张思
Owner CHINESE PEOPLES LIBERATION ARMY AIR FORCE GENERAL HOSPITAL
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