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Pharmaceutical composition and preparation method, preparation and application thereof

A technology of composition and medicine, which is applied in the field of pharmaceutical composition and its preparation, and can solve problems such as large daily temperature difference, poor resistance, and susceptibility to colds and diseases

Inactive Publication Date: 2016-07-06
昆明市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the four seasons of the year in Kunming, although the annual temperature difference is small, the daily temperature change is relatively large, and the daily temperature difference is large. The drastic change in temperature within a day makes it difficult for the human body to adapt in a short period of time, and the resistance is relatively weak. have a cold
In addition, it is located on a plateau, with dry climate, low air humidity, large evaporation, dryness, little rain, high winds, and the residents always like to eat spicy and dry food. These make Kunming people have basically similar characteristics of cough after colds in four seasons, severe cough, phlegm less, light yellow in color, sticky and difficult to cough, accompanied by dry throat, itchy throat, dry mouth, bitter mouth, dry and hard stools, and further development is mainly dry cough, no phlegm or less phlegm, which lasts for a long time, Repeated illness, protracted healing, long-term can lead to the occurrence of chronic pharyngitis and chronic bronchitis, which is more difficult to treat
At present, although there are many western medicines and Chinese patent medicines clinically used to treat cough, there is no Chinese patent medicine that is effective for cough characteristics in Kunming

Method used

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  • Pharmaceutical composition and preparation method, preparation and application thereof
  • Pharmaceutical composition and preparation method, preparation and application thereof

Examples

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preparation example Construction

[0015] The preparation method of the pharmaceutical composition of the present invention includes the steps of pretreatment, drying, crushing and sieving, specifically including:

[0016] A. Pretreatment: Weigh respectively according to the proportioning ratio of raw materials, and after mixing, extract, filter, and concentrate to obtain an extract with a relative density of 1.1 to 1.3 for subsequent use;

[0017] B. Drying: drying the pretreated extract until the moisture content is 6-8% to obtain the primary product of the target object;

[0018] C. Crushing and sieving: crush the primary product of the target object through a 80-100 mesh sieve to obtain the target object.

[0019] The extraction described in step A is one of decoction, dipping and percolation.

[0020] The extraction is a decocting method.

[0021] The decoction method is to decoct and extract twice, adding water 8 to 10 times the weight of the raw material medicine for the first time, decocting and extra...

Embodiment 1

[0027] Prepare 10g of mulberry leaves, 6g of almonds, 12g of sand ginseng, 10g of Ophiopogon japonicus, 10g of Fritillaria japonicus, 15g of reed root, 15g of coix seed, 15g of winter melon kernel, 3g of tangerine peel, 10g of Poria cocos, 10g of Beijing pinellia, 15g of fried grain sprouts and fried malt 15g, placed in an extraction tank for extraction twice, the first time adding 8 times the weight of water, decocting and extracting at 80°C for 1.5h; The filtrates were combined and concentrated into an extract with a relative density of 1.2; dried to a water content of 6%, pulverized and passed through an 80-mesh sieve to obtain the target pharmaceutical composition.

Embodiment 2

[0029] Prepare 8g of mulberry leaves, 5g of almonds, 10g of ginseng, 8g of Radix Ophiopogon, 8g of Fritillaria, 10g of reed root, 10g of coix seed, 10g of winter melon kernel, 2g of tangerine peel, 8g of Poria cocos, 8g of Beijing pinellia, 10g of fried grain sprouts and fried malt 10g, placed in an extraction tank for extraction twice, the first time adding 9 times the weight of water and decocting at 90°C for 1.5h; the second time adding 8 times the weight of water at 100°C for 1.0h, filtering, The filtrates were combined and concentrated into an extract with a relative density of 1.3; dried to a moisture content of 7%, pulverized and passed through an 80-mesh sieve to obtain the target pharmaceutical composition.

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Abstract

The invention discloses a pharmaceutical composition and a preparation method, a preparation and application thereof.The pharmaceutical composition comprises, by weight, 8-12 parts of Folium Mori, 5-7 parts of Almond, 10-14 parts of Radix Adenophorae, 8-12 parts of Radix Ophiopogonis, 8-12 parts of Bulbus Fritillariae Thunbergii, 10-20 parts of Rhizoma Phragmitis, 10-20 parts of Semen Coicis, 10-20 parts of wax gourd seed, 2-4 parts of Pericarpium Citri Reticulatae, 8-12 parts of Poria, 8-12 parts of processed pinellia tuber, 10-20 parts of stir-fried Fructus Setariae Germinatus,10-20 parts of roasted Fructus Hordei Germinatus and is prepared through pretreatment, uniform mixing, drying and grinding prior to sieving.The preparation method includes the steps of pretreatment, drying and grinding prior to sieving.The preparation can be powder, tablets, capsules, granules, oral liquid, dripping pills or honeyed pills prepared by adding pharmaceutically acceptable minor ingredients into the pharmaceutical composition.The application refers to application of the pharmaceutical composition to preparation of heat-clearing, dryness-moistening and cough-relieving medicines.The pharmaceutical composition is capable of clearing heat, nourishing yin, moistening dryness and relieving cough through compatibility of all traditional Chinese medicines in the formula.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparation, and in particular relates to a pharmaceutical composition, a preparation method, preparation and application thereof. Background technique [0002] In the four seasons of the year in Kunming, although the annual temperature difference is small, the daily temperature change is relatively large, and the daily temperature difference is large. The drastic change in temperature within a day makes it difficult for the human body to adapt in a short period of time, and the resistance is relatively weak. Suffering from a cold. In addition, it is located on a plateau, with dry climate, low air humidity, large evaporation, dryness, little rain, high winds, and the residents always like to eat spicy and dry food. These make Kunming people have basically similar characteristics of cough after colds in four seasons, severe cough, phlegm less, light yellow in color, sticky and...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61P11/14A61P11/00
CPCA61K36/8998A61K36/076A61K36/23A61K36/34A61K36/342A61K36/42A61K36/605A61K36/736A61K36/752A61K36/8888A61K36/8966A61K36/8968A61K36/899A61K36/8994A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 陆家龙魏丹霞陆玉姬余晓玲顾力华施兴黔陈斌杨海玲陈云山
Owner 昆明市中医医院
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