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Anti-fatigue traditional Chinese medicine combined extract and its preparation method and use

An extract and anti-fatigue technology, applied in the field of traditional Chinese medicine combination and its extract, can solve side effects and other problems, and achieve fatigue injury prevention, no toxic side effects, and significant effects of fatigue injury

Inactive Publication Date: 2016-07-06
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most of the anti-fatigue drugs currently on the market are some chemical drugs, and these drugs also bring different degrees of side effects while exerting therapeutic effects

Method used

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  • Anti-fatigue traditional Chinese medicine combined extract and its preparation method and use
  • Anti-fatigue traditional Chinese medicine combined extract and its preparation method and use
  • Anti-fatigue traditional Chinese medicine combined extract and its preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The preparation of embodiment 1 Chinese medicine extract (one)

[0035]Take Acanthopanax, Radix Astragali and Codonopsis pilosula at a ratio of 5:5:1, wash them, put them into an extraction container, add 8-10 times of distilled water, and decoct twice, each time for 1.5 hours. The medicinal solutions extracted several times were combined, concentrated, and ethanol was added for alcohol precipitation, and the supernatant after alcohol precipitation was concentrated and dried under reduced pressure to obtain extract C1.

Embodiment 2

[0036] The preparation of embodiment 2 Chinese medicine extract (two)

[0037] Take Acanthopanax, Radix Astragali and Codonopsis pilosula at a ratio of 5:5:1, wash them, put them in an extraction container and add 8-10 times of distilled water to decoct twice, each decocting time is 1.5 hours. Combine the medicinal liquids extracted several times, concentrate them to a specific gravity of 1.01-1.05, add ethanol to contain 70-80% alcohol for alcohol precipitation, concentrate the supernatant after alcohol precipitation to a specific gravity of 1.01-1.04, pass the extract through AB- 8 macroporous resin columns. Flow rate 1.5-1.8BV / h, collect 30-75% ethanol eluted parts, concentrate and dry under reduced pressure to obtain the extract.

Embodiment 3

[0038] The preparation of embodiment 3 Chinese medicine extract (three)

[0039] Take Acanthopanax, Radix Astragali and Codonopsis pilosula at a ratio of 5:5:1, wash them, put them in an extraction container and add 8-10 times of distilled water to decoct twice, each decocting time is 1.5 hours. Combine the medicinal liquids extracted several times, concentrate to a specific gravity of 1.01-1.05, add ethanol to 70-80% alcohol content for alcohol precipitation, concentrate the supernatant after alcohol precipitation to a specific gravity of 1.01-1.04, pass the extract through ZTC- 1 macroporous resin column. Flow rate 1.5-1.8BV / h, collect 30-75% ethanol elution site, eluate is concentrated and dried under reduced pressure to obtain extract.

[0040] Wherein, extract C2 is obtained by collecting 30% ethanol eluted parts, concentrated and dried under reduced pressure, and collected 50%-70% ethanol eluted parts, concentrated and dried under reduced pressure to obtain extract C3. ...

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Abstract

The invention relates to anti-fatigue traditional Chinese medicine combined extract. The anti-fatigue traditional Chinese medicine combined extract is prepared from manyprickle acanthopanax root, radix astragali and radix changii according to a weight part ratio of 5: 5: 1. The invention also provides a preparation method and a use of the anti-fatigue traditional Chinese medicine combined extract. The traditional Chinese medicine extract mainly comprises lignin, saponin and flavonoid compounds. A pharmacological experiment proves that the extract can substantially relieve fatigue damage in fatigue and special environments, has high safety and can be used for preparation of an anti-fatigue drug or food.

Description

technical field [0001] The invention relates to a combination of traditional Chinese medicine and its extract, in particular, an extract of the combination of traditional Chinese medicine for anti-fatigue, especially special environmental fatigue damage, its preparation method and application. Background technique [0002] Fatigue is a comprehensive response of many physiological and biochemical changes in the body caused by multiple factors. Divided into physical fatigue and psychological fatigue, physical fatigue mainly manifests as a decline in exercise ability, and psychological fatigue mainly manifests as negative changes in behavior and will. Fatigue is a normal physiological phenomenon within a certain range. With the faster and faster pace of social work and life, the pressure from work, family, housing, medical care, interpersonal relationships, etc. makes people in a state of tension for a long time, which is easy to cause fatigue. If physical fatigue and psycholo...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61P39/00A23L1/29A23G4/12
Inventor 黄宝康季晓陈璐张乃丹王晓钰
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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