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Domestic rabbit traumatic osteoarthritis model making device

An osteoarthritis and traumatic technology, applied in the field of rabbit traumatic osteoarthritis model maker, can solve the problems affecting the experimental results, controllable operation, cartilage damage, etc., and achieve good experimental results and high reliability , to achieve the effect of impact capacity and force area

Active Publication Date: 2016-06-29
THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current routine operation only uses instruments such as blades or bone drills to violently damage the cartilage, and it is impossible to control the degree of cartilage damage.
Different degrees of cartilage damage lead to significant differences in the degree of lesions in osteoarthritis models, which will directly affect the comparability of different osteoarthritis models and affect the experimental results.

Method used

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  • Domestic rabbit traumatic osteoarthritis model making device
  • Domestic rabbit traumatic osteoarthritis model making device
  • Domestic rabbit traumatic osteoarthritis model making device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Such as figure 1 and figure 2 As shown, this embodiment provides a rabbit traumatic osteoarthritis model maker, which is sequentially connected with an impact unit, a connecting unit and two legging units from top to bottom.

[0037] The impact unit includes an impact rod 1, and one end (front end) of the impact rod 1 is detachably provided with an impact head 2. The impact head 2 in this embodiment is a conical impact head, and the cone impact head has a larger diameter. A plug-in is provided at one end, and a mounting hole is provided at one end of the striking rod 1, and the plug-in is inserted into the mounting hole.

[0038] A sleeve 3 is provided on the outer movable sleeve of the striking rod 1, and a first baffle plate 31 and a second baffle plate 32 are respectively provided at both ends of the sleeve 3, and the first baffle plate 31 and the second baffle plate 32 are respectively provided with a first through hole and a second through hole, and the striking...

Embodiment 2

[0043] Such as figure 1 with figure 2 As shown, this embodiment provides a rabbit traumatic osteoarthritis model maker, which is sequentially connected with an impact unit, a connecting unit and two legging units from top to bottom.

[0044] The impact unit includes an impact rod 1, and one end (front end) of the impact rod 1 is detachably provided with an impact head 2. The impact head 2 in this embodiment is a conical impact head, and the cone impact head has a larger diameter. There is a plug-in at the end, the outside of the plug-in is provided with an external thread, one end of the striking rod 1 is provided with a mounting hole, and the inside of the mounting hole is provided with an internal thread, and the plug-in is threadedly connected in the mounting hole. .

[0045] A sleeve 3 is provided on the outer movable sleeve of the striking rod 1, and a first baffle plate 31 and a second baffle plate 32 are respectively provided at both ends of the sleeve 3, and the fir...

Embodiment 3

[0052] Such as figure 1 with figure 2 As shown, this embodiment provides a rabbit traumatic osteoarthritis model maker, which is sequentially connected with an impact unit, a connecting unit and two legging units from top to bottom.

[0053] The striking unit includes a striking rod 1 , one end (front end) of the striking rod 1 is detachably provided with a striking head 2 , and the other end (rear end) of the striking rod 1 is provided with a spherical handle 11 .

[0054] The impact head 2 described in this embodiment is a conical impact head, the larger end of the conical impact head is provided with an insert, the outer side of the insert is provided with an external thread, and one end of the impact rod 1 is provided with a mounting hole, The inner side of the mounting hole is provided with an internal thread, and the insert is screwed into the mounting hole.

[0055] A sleeve 3 is provided on the outer movable sleeve of the striking rod 1, and a first baffle plate 31 ...

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Abstract

The invention relates to a domestic rabbit traumatic osteoarthritis model making device. An impact head is arranged at one end of an impact rod of an impact unit in a detachable mode, and a sleeve movably sleeves the outer side of the impact rod; a spring covers the outer side of the impact rod which is located in the sleeve; when the spring is at a natural length, a shielding sheet clings to a second baffle plate; when the domestic rabbit traumatic osteoarthritis model making device is used, the relative positions and included angles of the impact unit, a connecting unit and a leg wrapping unit are regulated and fixed, when the rear end of the impact rod is pulled by external force, the impact rod and the shielding sheet are integrally moved backwards and the spring becomes shrunk, and meanwhile, the shielding sheet and the second baffle plate are separated; the spring, after being released, can drive the impact head of the impact rod to impact upon an object in the front, so that a controllable operation over a cartilage injury degree can be achieved by regulating the strength of the exerted external force; various osteoarthritis models are comparable; and the domestic rabbit traumatic osteoarthritis model making device is good in experimental effect and high in experimental data reliability.

Description

technical field [0001] The invention belongs to a biological trauma device for animal experiments, in particular to a rabbit traumatic osteoarthritis model maker. Background technique [0002] At present, the pathogenesis of osteoarthritis is not yet clear, and the treatment of osteoarthritis is still a worldwide problem. A large number of medical workers are conducting in-depth research on this disease. Due to ethical constraints, it is often impossible to conduct research on patients with osteoarthritis in medical research, so animal research occupies a very important position. [0003] The first step in animal research on osteoarthritis is to make osteoarthritis models, among which the rabbit traumatic osteoarthritis model is the most classic and is widely used in osteoarthritis research. There are two main methods for making traumatic osteoarthritis models in rabbits: (1) cutting off the cruciate ligament of the knee joint of the rabbit’s hind leg to cause joint instabi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D1/00
CPCA61D1/00
Inventor 何金深巴宏亮吴松王永娟李明波廖云杰李利丰王梓力郑陈煌夏晗松
Owner THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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