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Analysis equipment and method for simultaneously measuring CRP (C-Reactive Protein) and blood routine

An analysis method and blood routine technology, which is applied in the field of blood analyzers, can solve the problems of not being able to measure CRP and blood routine at the same time, cumbersome and slow CRP operations, and achieve the effects of low cost, convenient operation, and small size

Inactive Publication Date: 2016-06-22
SHENZHEN DYMIND BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to provide an analysis device and method that can measure CRP and blood routine at the same time, aiming to solve the problem that the existing technology cannot measure CRP and blood routine at the same time, and the routine detection of CRP is cumbersome and slow.

Method used

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  • Analysis equipment and method for simultaneously measuring CRP (C-Reactive Protein) and blood routine
  • Analysis equipment and method for simultaneously measuring CRP (C-Reactive Protein) and blood routine
  • Analysis equipment and method for simultaneously measuring CRP (C-Reactive Protein) and blood routine

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Embodiment 1

[0074] Such as figure 1 As shown, the present invention provides an analytical device capable of simultaneously measuring CRP and blood routine, including: a laser measuring device 1, a sampling needle 2, a CRP measuring device 3, a CRP reaction tank 4, a red blood cell counting tank 5, a hemoglobin measuring device 6, a white blood cell Reaction pool 7 , diluent 8 , first hemolyzing agent 9 , antibody reagent 10 , second hemolyzing agent 11 , third hemolyzing agent 12 , waste liquid discharge device 13 and delivery device 14 .

[0075] Wherein, the diluent 8 is a reagent for diluting the sample and cleaning; the first hemolysis agent 9 is a buffer solution for dissolving red blood cells in the CRP measurement channel and providing a CRP reaction; the antibody reagent 10 is a reagent for participating in the CRP antigen-antibody reaction; the second hemolysis Agent 11 is a DIFF (white blood cell classification channel) hemolytic agent, which functions to dissolve red blood cel...

Embodiment 2

[0109] see Figure 5 The difference between the second embodiment and the first embodiment is that the leukocyte DIFF measurement, the white blood cell Baso measurement and the hemoglobin measurement share a hemolytic agent, the third hemolytic agent 12 in the first embodiment is omitted, only the second hemolytic agent 11 Add the white blood cell reaction pool 7 alone.

[0110] The analysis equipment provided in the second embodiment includes: a laser measuring device 1, a sampling needle 2, a CRP measuring device 3, a CRP reaction tank 4, a red blood cell counting tank 5, a hemoglobin measuring device 6, a white blood cell reaction tank 7, a diluent 8, a first Hemolyzing agent 9 , antibody reagent 10 , second hemolyzing agent 11 , waste liquid discharge device 13 and delivery device 14 .

[0111]The entrance of the laser measuring device 1 is connected to the conveying device 14, and the outlet is connected to the waste liquid discharge device 13. The sample in the leukocyt...

Embodiment 3

[0138] see Figure 7 , the present invention also provides another embodiment, the difference between this embodiment and the first embodiment is that the first hemolytic agent 9 is omitted, and only an antibody reagent 10 is added to the CRP measurement pool 4 . The second hemolytic agent 11 is replaced by the fourth hemolytic agent 13; it is necessary to take into account the hemolytic function of the CRP measurement channel. The functions of the fourth hemolytic agent 13 are as follows: 1. Dissolving red blood cells, different treatment of various types of white blood cells, can be used for DIFF classification measurement; Red blood cells can be used for hemoglobin measurement; 4. Red blood cells are dissolved to prepare for CRP measurement.

[0139] The analysis equipment provided in the second embodiment includes: laser measuring device 1, sampling needle 2, CRP measuring device 3, CRP reaction tank 4, red blood cell counting tank 5, hemoglobin measuring device 6, white ...

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Abstract

The invention discloses analysis equipment and method for simultaneously measuring CRP (C-Reactive Protein) and blood routine. The method comprises the following steps: sucking a sample through a sampling needle; evacuating a CRP measuring tank; then adding a first hemolytic agent into the CRP measuring tank; moving the sampling needle to the CRP measuring tank and adding one part of the blood sample into the CRP measuring tank; evacuating a white blood cell reaction tank, and adding diluting liquid into the white blood cell reaction tank; adding one part of the blood sample into the white blood cell reaction tank and sufficiently and uniformly mixing; sucking one part of a mixed sample from the uniformly mixed sample; evacuating a red blood cell counting tank, and adding the diluting liquid into the red blood cell counting tank; adding the mixed sample into the red blood cell counting tank; counting up red blood cells and blood platelets, and outputting a measuring result. With the adoption of the analysis equipment and method, the CRP test and five types of blood routine tests can be performed simultaneously through the same tube of whole blood, so that the operation is very convenient; a system is simple and reliable, low in cost and small in size, and is very suitable for primary hospitals.

Description

technical field [0001] The invention relates to a blood analyzer, in particular to an analysis device and method capable of simultaneously measuring CRP and blood routine. Background technique [0002] CRP (C-reactive protein) is a part of the body's non-specific immune mechanism. It can activate the classic pathway of complement, enhance the phagocytosis of white blood cells, regulate the function of lymphocytes or monocyte / macrophage system, and promote the production of macrophage tissue factor. CRP can also be detected in atherosclerotic plaques. CRP rises rapidly several hours after the inflammation begins, and reaches its peak within 48 hours. With the lesions subsiding and tissue and function recovering, CRP drops to normal levels accordingly. Therefore, the test results of CRP have extremely important clinical value in the hospital. [0003] At present, there are two main methods for CRP detection: 1. To detect CRP in a biochemical analyzer, centrifuge the blood sa...

Claims

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Application Information

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IPC IPC(8): G01N21/84G01N15/10G01N33/50
CPCG01N21/84G01N15/10G01N33/5005G01N33/5094G01N2015/1006
Inventor 刘治志宋健
Owner SHENZHEN DYMIND BIOTECH
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