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Pharmaceutical preparation for promoting vascular remodeling and fracture healing after bone fracture

A pharmaceutical preparation and vascular reconstruction technology, applied in the direction of drug combination, medical raw materials derived from algae, medical preparations containing active ingredients, etc., can solve the problems of painful healing of patients, easy to leave sequelae, long time of taking medicine, etc., to achieve the goal of traditional Chinese medicine Clear pharmacology, non-toxic and side effects, and the effect of improving microcirculation

Inactive Publication Date: 2016-06-22
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the treatment of fractures is mainly based on surgical reduction and internal fixation, manipulative reduction and external fixation, combined with external application of drugs, and bed rest for recuperation. Bed rest causes joint adhesions, resulting in dysfunctional muscle atrophy, accompanied by many sequelae caused by too long treatment process, causing life-long pain to the patient
Often the course of treatment is long, which brings pain to patients and slow healing, high cost, long time of taking medicine, inconvenient taking, and unsatisfactory curative effect, which is easy to leave sequelae

Method used

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  • Pharmaceutical preparation for promoting vascular remodeling and fracture healing after bone fracture

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] Embodiment 1: A pharmaceutical preparation for vascular reconstruction and fracture healing after fracture, comprising the following Chinese medicinal materials in parts by weight:

[0071] 10 grams of Epimedium, 10 grams of Angelica, 10 grams of Achyranthes bidentata, 10 grams of Duhuo, 3 grams of Digong vine, 7 grams of Fritillaria, 5 grams of Dazizhu, 3 grams of Wood Beetle, 5 grams of frankincense, 5 grams of Chinese pine knot, 3 grams of Jiangxiang, 5 grams of sea breeze algae, 5 grams of Shenjincao, 3 grams of madder, 10 grams of cooked Sanqi, 6 grams of licorice, 10 grams of burdock, 5 grams of wolfberry, 5 grams of Qingfengteng, and 3 grams of dried lacquer.

[0072] Concrete preparation method is:

[0073] 1) Epimedium, Angelica, Achyranthes bidentata, Lovage, Digong vine, Fritillaria chinensis, Big Purple Pearl, Wood Beetle, Frankincense, Turpentine, Dalbergia, Sea Breeze Algae, Streptomyces sinensis, Rubia, Licorice, Burdock Seed, Lycium barbarum , Qingfengt...

Embodiment 2

[0078] Embodiment 2: A pharmaceutical preparation for vascular reconstruction and fracture healing after fracture, comprising the following Chinese medicinal materials in parts by weight:

[0079] Epimedium 25g, Angelica 15g, Achyranthes bidentata 15g, Duhuo 16g, Digong vine 8g, Fritillaria 14g, Dazizhu 10g, Wood beetle 8g, Frankincense 11g, pine knot 10g, 8 grams of Jiangxiang, 11 grams of sea breeze algae, 10 grams of Shenjincao, 8 grams of madder, 15 grams of cooked notoginseng, 9 grams of licorice, 20 grams of burdock, 15 grams of wolfberry, 9 grams of Qingfengteng, and 8 grams of dried lacquer. Concrete preparation method is:

[0080] 1) Epimedium, Angelica, Achyranthes bidentata, Lovage, Digong vine, Fritillaria chinensis, Big Purple Pearl, Wood Beetle, Frankincense, Turpentine, Dalbergia, Sea Breeze Algae, Streptomyces sinensis, Rubia, Licorice, Burdock Seed, Lycium barbarum , Qingfengteng and dry lacquer are weighed according to weight, crushed, soaked in pure water, ...

Embodiment 3

[0085] Embodiment 3: A pharmaceutical preparation for vascular reconstruction and fracture healing after fracture, comprising the following Chinese medicinal materials in parts by weight:

[0086] Epimedium 18g, Angelica 13g, Achyranthes bidentata 13g, Duhuo 13g, Digong vine 5g, Fritillaria 11g, Purple Pearl 8g, Woodbeet 6g, Frankincense 8g, Turpentine 8g, 6 grams of Jiangxiang, 8 grams of sea breeze algae, 7.5 grams of Shenjincao, 6 grams of madder, 13.5 grams of cooked notoginseng, 7.5 grams of licorice, 15 grams of burdock, 10 grams of wolfberry, 7 grams of Qingfengteng, and 6.5 grams of dried lacquer.

[0087] Concrete preparation method is:

[0088] 1) Epimedium, Angelica, Achyranthes bidentata, Lovage, Digong vine, Fritillaria chinensis, Big Purple Pearl, Wood Beetle, Frankincense, Turpentine, Dalbergia, Sea Breeze Algae, Streptomyces sinensis, Rubia, Licorice, Burdock Seed, Lycium barbarum , Qingfengteng and dry lacquer were weighed according to the weight, crushed, so...

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PUM

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Abstract

The invention relates to a pharmaceutical preparation for promoting vascular remodeling and fracture healing after bone fracture and a preparation method thereof. The pharmaceutical preparation comprises the following ingredients in parts by weight: 10-25 parts of epimedium, 10-15 parts of angelica, 10-15 parts of achyranthes root, 10-16 parts of heracleum hemsleyanum michaux, 3-8 parts of erycibe obtusifolia, 7-14 parts of rhizoma bolbostemmae, 5-10 parts of callicarpa randaiensis, 3-8 parts of ground beetle, 5-11 parts of frankincense, 5-10 parts of lignum pini nodi, 3-8 parts of lignum dalbergiae odoriferae, 5-11 parts of futokadsura stem, 5-10 parts of lycopodium clavatum, 3-8 parts of madder, 10-15 parts of cooked panax notoginseng, 6-9 parts of licorice, 10-20 parts of burdock fruit, 5-15 parts of Chinese wolfberry, 5-9 parts of caulis sinomenii and 3-8 parts of dried lacquer. The pharmaceutical preparation provided by the invention is clear in pharmacology of traditional Chinese medicines, is prepared from matched medicines, is capable of promoting circulation of qi and blood and strengthening tendons and bones, has an additional hematopoietic function, and has the effects of strengthening the spleen and replenishing qi, tonifying the liver and kidneys, increasing the resistance of patients, improving microcirculation, activating bone cells and enhancing the action of reunion of bones, thereby effectively promoting vascular remodeling and fracture healing.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine treatment, and in particular relates to a pharmaceutical preparation for treating post-fracture blood vessel reconstruction and fracture healing and a preparation method thereof. Background technique [0002] With the rapid development of all walks of life in the 21st century, the expansion of industrial scale and the convenience of transportation, the proportion of sprains and fractures is increasing. People often cause great harm to their bodies in a few seconds of accidents. months to recover. What's more, serious disability is caused, which brings inconvenience to the life of the patient and burdens the family and society. The main method for the treatment of bone injuries at present is to fix the affected part of the fracture patient and rely on natural healing. Doctor trained in Western medicine has not yet appeared the medicine for the treatment of fracture, often adopt reducti...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P19/08A61K35/64
CPCA61K9/1652A61K35/63A61K36/02A61K36/11A61K36/15A61K36/21A61K36/22A61K36/232A61K36/258A61K36/28A61K36/296A61K36/324A61K36/39A61K36/42A61K36/48A61K36/484A61K36/59A61K36/74A61K36/815A61K36/85A61K2236/333A61K2236/331A61K9/4866A61K2236/39A61K2300/00
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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