Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Biological agent for repairing irritable bowel mucosa damage and preparation method thereof

A biological preparation, intestinal mucosal technology, applied in the direction of bacteria, application, food science, etc. used in food preparation, can solve the problem of lack of good repair methods, and achieve the promotion of stress-induced intestinal mucosal damage repair and easier absorption Utilize, effective effect

Inactive Publication Date: 2016-06-01
SHANGHAI PROBIOTIK HEALTH TECH
View PDF6 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above existing technologies and related research results all use probiotics to protect or repair general gastrointestinal damage, and for intestinal damage caused by oxidative stress, especially for the generation of a large number of free radicals Intestinal mucosal injury, currently there is no good repair method

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0032] The invention provides a method for preparing a biological preparation for repairing stress intestinal mucosal injury, which is characterized in that it comprises:

[0033] Step 1: Mix according to the weight ratio of 20-35 parts of Saccharomyces cerevisiae, 25-40 parts of Lactobacillus acidophilus, and 20-35 parts of Lactobacillus plantarum to obtain the mixed bacteria, add it to the brown sugar water medium, and in 28-32 Cultivate in airtight conditions at ℃ until the pH is less than 3.60-4.00, and then continue to cultivate for 20-30 days to obtain composite bacteria;

[0034] Step 2: Mix according to the weight ratio of 10-25 parts of kudzu root, 15-25 parts of seabuckthorn, 20-30 parts of grape seed, 1-3 parts of brown sugar, and 40-60 parts of water to obtain a compound medium;

[0035] Step 3: adding the composite bacteria to the composite culture medium, and culturing in a sealed environment at 28-32°C for 30-45 days to obtain a composite fermentation product; ...

Embodiment 1

[0058] A method for preparing a biological preparation for repairing stress intestinal mucosal damage, comprising:

[0059] The first step: cultivation of strains: insert the Saccharomyces cerevisiae strains (Saccharomycescerevisiae, ACCC20065) purchased from China Agricultural Microorganism Culture Collection and Management Center into the Erlenmeyer flask of potato liquid medium, shake at 28°C, 180-220rpm Cultivate for 48 hours, and take out after the medium is turbid; Lactobacillus acidophilus strains (Lactobacillus acidophilus, ACCC10637), Lactobacillus plantarum strains (Lactobacillus plantarum, ACCC11118) were respectively inserted into the Erlenmeyer flasks of MRS liquid medium, at 37 Cultivate at ℃ for 48 hours, take out the medium after it becomes turbid, and then store it in a 4℃ refrigerator for later use;

[0060] The second step: mix according to the weight ratio of 35 parts of Saccharomyces cerevisiae, 30 parts of Lactobacillus acidophilus, and 35 parts of Lactob...

Embodiment 2

[0066] A method for preparing a biological preparation for repairing stress intestinal mucosal damage, comprising:

[0067] The first step: cultivation of strains: insert the Saccharomyces cerevisiae strains (Saccharomycescerevisiae, ACCC20065) purchased from China Agricultural Microorganism Culture Collection and Management Center into the Erlenmeyer flask of potato liquid medium, shake at 28°C, 180-220rpm Cultivate for 48 hours, and take out after the medium is turbid; Lactobacillus acidophilus strains (Lactobacillus acidophilus, ACCC10637), Lactobacillus plantarum strains (Lactobacillus plantarum, ACCC11118) were respectively inserted into the Erlenmeyer flasks of MRS liquid medium, at 37 Cultivate at ℃ for 48 hours, take out the medium after it becomes turbid, and then store it in a 4℃ refrigerator for later use;

[0068] The second step: mix according to the weight ratio of 20 parts of Saccharomyces cerevisiae, 35 parts of Lactobacillus acidophilus, and 30 parts of Lactob...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a biological agent for repairing irritable bowel mucosa damage and a preparation method thereof. The method comprises the steps that brewer's yeast, lactobacillus acidophilus and lactobacillus plantarum are mixed to obtain mixed bacteria; the mixed bacteria are added to a brown sugar water culture medium, airtight culture is carried out till the pH is smaller than 4.00, then culture continues to be carried out for 20-30 days, and compound bacteria are obtained; kudzu vine roots, sea-buckthorns, grape seeds, brown sugar and water are mixed to obtain a compound medium; the compound bacteria are added to the compound medium, airtight culture is carried out for 30-45 days, and a compound fermentation product is obtained; then soaking, elution, concentrating, sterilizing and forming are carried out, and the biological agent is obtained. The effective ingredients of plants are converted through the microorganism compound fermentation technology, and therefore the product has the advantages of being easier to absorb and utilize, remarkable in treatment effect and the like, especially free radicals can be scavenged, intestinal flora balance can be adjusted, repairing of the irritable bowel mucosa damage is promoted, and the biological agent for repairing the irritable bowel mucosa damage is natural.

Description

technical field [0001] The invention relates to the field of health food, in particular to a biological preparation, in particular to a biological preparation for repairing stress intestinal mucosal damage and a preparation method thereof. Background technique [0002] The intestinal tract is not only the main place for digestion and absorption of nutrients in the human body, but also the most vulnerable target organ in multiple organ dysfunction syndrome and systemic inflammatory response syndrome. The intestinal mucosal barrier of normal human body is composed of mechanical barrier, biofilm barrier and immune barrier. A complete intestinal mucosal defense system can effectively prevent harmful substances in the intestinal tract from entering the systemic circulation. [0003] At present, when the human body is under stress, its intestines will produce a large number of free radicals, which will cause damage to the intestinal mucosa. Furthermore, the clinical manifestatio...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A23L33/10A23L33/135A23L33/14
CPCA23V2002/00A23V2400/113A23V2400/169A23V2200/30A23V2200/32A23V2250/76
Inventor 江瀚
Owner SHANGHAI PROBIOTIK HEALTH TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com