Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of SNP site of CNTN4 gene and detection primer and kit thereof

A site and gene technology, applied to the application of CNTN4 gene SNP site and its detection primers and kits, can solve the problems of lack of dyslexia susceptibility loci, no detection kits for dyslexia susceptibility genes, etc. Achieve the effect of preventing and reducing dyslexia, economical and convenient detection means, and strong adaptability

Inactive Publication Date: 2016-05-25
CAPITALBIO EHEALTH SCI & TECH BEIJING CO LTD
View PDF4 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the gene-wide association analysis of dyslexia in the Chinese population, and there is no large-scale systematic genome-wide association analysis of dyslexia in the Chinese population, so there is a lack of susceptibility loci for Chinese dyslexia
Therefore, there is no detection kit for dyslexia susceptibility genes for the Chinese population

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of SNP site of CNTN4 gene and detection primer and kit thereof
  • Application of SNP site of CNTN4 gene and detection primer and kit thereof
  • Application of SNP site of CNTN4 gene and detection primer and kit thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A total of 4338 people were taken as samples of school-age children, which were three independent population samples, and the size of each population was 1976, 1143, and 1219 individuals.

[0046] Refer to the literature Siok, W.T., Niu, Z., Jin, Z., Perfetti, C.A. & Tan, L.H. The above-mentioned samples were screened according to Chinese scores, reading scores and Raven scores. The test results showed that among the 4338 people, a total of 2123 people had dyslexia.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of biology, in particular to an application of an SNP site of a CNTN4 gene and a detection primer and kit thereof. The invention discovers the SNP site rs12636975 on the CNTN4 gene which reaches a full genome correlation analysis level of significance through full genome correlation analysis, and provides a detection kit and detection method for evaluating risk of people with reading disorder. The experimental result is from Chinese people and has very strong adaptability to Chinese people, and the research sample size is the biggest so far. The detection means is economical, convenient and favorable for large-scale popularization in people.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to the application of CNTN4 gene SNP sites, detection primers and kits thereof. Background technique [0002] Dyslexia is a neurologically-based developmental disorder manifested by impaired reading and spelling that is not explained by delayed cognitive development or mental retardation. Developmental dyslexia is the most common learning disability in school-age children, can persist into adulthood, and can affect social adjustment. The prevalence of dyslexia in Chinese school-age population ranges from 4% to 13%. It is generally believed that dyslexia is the result of the combined effects of genetic and environmental factors. [0003] In the prior art, the diagnostic criteria for dyslexia mainly refer to the literature Siok, W.T., Niu, Z., Jin, Z., Perfetti, C.A. & Tan, L.H. –6 (2008). Screening is based on Chinese scores, reading scores and Raven scores. This method is cumbersom...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68C12N15/11
CPCC12Q1/6883C12Q2600/156
Inventor 孙义民王斌周禹稀
Owner CAPITALBIO EHEALTH SCI & TECH BEIJING CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com