Medicine composition for treating schizophrenia

A technology for schizophrenia and composition, which is applied in the directions of drug combination, medical preparation containing active ingredients, pharmaceutical formula, etc., can solve the problem that the degree of improvement cannot meet the requirements of patients' social function rehabilitation and the like

Inactive Publication Date: 2016-05-04
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the new antipsychotic drugs can improve the negative symptoms of schizophrenia to a certain extent, the degree of improvement fundamentally cannot meet the requirements of social function rehabilitation of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: the pharmaceutical composition for the treatment of schizophrenia and its preparation method

[0034] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating schizophrenia are: 4830g of Shenggu oil, 4640g of crotonopoxy 185g, 191g of corydalis;

[0035] Preparation:

[0036] (1) According to the ratio of raw materials, take Shenggu oil, scutellaria, crotonepoxy, and corydalis, mix well, use ethanol with a concentration of 24% by weight as a solvent, and extract by warm soaking at 25.5°C, and the number of extractions is 20 time, each extraction time is 2.5 hours, each solvent consumption is 38.5 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.16, filters, The medicinal liquid passes through the DM18 macroporous adsorption resin column, and is first eluted with water, and then eluted with...

Embodiment 2

[0039] Embodiment 2: the pharmaceutical composition for the treatment of schizophrenia and its preparation method

[0040] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of schizophrenia are: 4800g Shenggu oil 4680g crotonepoxy 180g 192g corydalis mint;

[0041] Preparation:

[0042] (1) According to the ratio of raw materials, take Shenggu oil, scutellaria, crotonepoxy, and corydalis, mix well, use ethanol with a concentration of 24% by weight as a solvent, and extract by warm soaking at 25.5°C, and the number of extractions is 20 time, each extraction time is 2.5 hours, each solvent consumption is 38.5 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.16, filters, The medicinal liquid passes through the DM18 macroporous adsorption resin column, and is first eluted with water, and then eluted with 42.5...

Embodiment 3

[0045] Embodiment 3: the pharmaceutical composition for the treatment of schizophrenia and its preparation method

[0046] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of schizophrenia are: 4,860g, 4,600g, 190g, 190g, 190g, 190g, of crotonepoxy, Xinggu oil;

[0047] Preparation:

[0048] (1) According to the ratio of raw materials, take Shenggu oil, scutellaria, crotonepoxy, and corydalis, mix well, use ethanol with a concentration of 24% by weight as a solvent, and extract by warm soaking at 25.5°C, and the number of extractions is 20 time, each extraction time is 2.5 hours, each solvent consumption is 38.5 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.16, filters, The medicinal liquid passes through the DM18 macroporous adsorption resin column, and is first eluted with water, and then eluted wit...

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Abstract

The invention discloses a medicine composition for treating schizophrenia and a preparing method of the medicine composition. The medicine composition is prepared from bumalda bladdernut fruits or roots, whole grass of thyrocarpus sampsonii hance, crotepoxide and corlumine according to a proportion. The medicine composition can be prepared into various dosage forms according to conventional preparation technologies, and is significant in treatment effect when used for treating schizophrenia.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating schizophrenia and a preparation method thereof. Background technique [0002] Schizophrenia belongs to the category of epilepsy and madness in Chinese medicine, and its location lies in the mental mechanism. Regulating qi and relieving stagnation, unobstructing the mind, and empathy are the main methods of treatment; the pathogenesis of mad disease is phlegm, fire, blood stasis, obstruction of the heart orifice, imbalance of yin and yang, and loss of control of form and spirit. Adjusting yin and yang and recovering divine mechanism are the fundamental methods. According to modern medicine, schizophrenia is a group of mental diseases with unknown etiology. Its clinical classification is quite detailed, and its treatment has developed rapidly, especially in controlling acute symptoms. Tendencies, repeated...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/30A61P25/18A61K31/336A61K31/4725
CPCA61K36/30A61K9/2031A61K9/2059A61K9/4866A61K31/336A61K31/4725A61K36/185A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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