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Granules for treating peptic ulcer and method for preparing granules

A technology for peptic ulcer and granules, which is applied in the field of granules for treating peptic ulcer and its preparation, can solve the problems of insoluble in water and loss of active ingredients, achieve good pain relief effect, improve drug efficacy and activity, and improve gastric mucosa Restorative effect

Inactive Publication Date: 2016-01-27
门源县雪草木生物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, traditional Chinese medicinal materials are mostly decocted in water, but some active ingredients are not easily soluble in water, or are lost during the decoction process. Therefore, in order to make better use of medicinal material resources, it is necessary to prepare pharmaceutical compositions method for research

Method used

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  • Granules for treating peptic ulcer and method for preparing granules
  • Granules for treating peptic ulcer and method for preparing granules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 granule of the present invention

[0025] 3 parts of zushima, 0.5 part of anisodina, 9 parts of dried ginger, 10 parts of seabuckthorn; first add 10 times the amount of 80% v / v ethanol solution to reflux for extraction once, extract for 1 hour, filter, the filtrate is set aside, and the filter residue is decocted with water 2 times, add 8 times of water each time, decoct for 30 minutes each time, combine the ethanol extract and water decoction, concentrate to a thick paste with a relative density of 1.22-1.25 (60°C), add dextrin, dextrin The total dosage is 1.5 times of the dry weight of the extract, wet granulated, and dried to obtain the pharmaceutical granules of the present invention.

[0026] The beneficial effects of the present invention are further demonstrated through specific test examples below.

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Abstract

The invention discloses granules for treating peptic ulcer. The granules comprise, by weight, 1-3 parts of daphne giraldii nitsche, 0.3-0.6 part of anisodus tanguticus, 6-10 parts of dried ginger and 6-10 parts of sea buckthorn. The granules have the advantages that the granules which are medicines have little medicine flavor owing to specific usage matching, gastric ulcer, duodenal ulcer and erosive gastritis can be effectively treated by the granules, and a novel medication option can be provided for clinically treating the peptic ulcer; as proved by efficacy tests, the efficacy activity of the granules can be improved by the aid of alcohol and water double-extraction modes, and the granules are beneficial to economically utilizing medicinal material resources.

Description

technical field [0001] The invention relates to a granule for treating peptic ulcer and a preparation method thereof. Background technique [0002] Peptic ulcer mainly refers to chronic ulcers that occur in the stomach and duodenum. Among them, gastric and duodenal ulcers refer to localized circular or oval full-thickness defects of the gastric and duodenal mucosa, the muscularis mucosa is penetrated, and fibrous scars are inevitably left after healing. Covered by epithelium, the muscularis mucosa cannot regenerate. The etiology can be summed up as the self-digestion of gastric mucosa by gastric acid and pepsin or the destruction of gastric mucosal barrier due to various reasons. In recent years, it has been considered that the formation of ulcers has an important relationship with Helicobacter pylori infection in the stomach. [0003] Chronic erosive gastritis, also known as verrucous gastritis or pimple-like gastritis, generally only sees dyspepsia symptoms such as full...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61P1/04
Inventor 徐继锋卞海军许婧
Owner 门源县雪草木生物药业有限公司
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