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Medicine composition for treating plasma cell mastitis and application of medicine composition

A composition and technology of mastitis, applied in the direction of drug combination, disease, medical formula, etc., can solve the problems of long-term unhealed fistula, easy recurrence, and unsatisfactory clinical treatment effect, so as to achieve no recurrence, less damage, and better effect Good results

Inactive Publication Date: 2016-01-20
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It mainly occurs in young and middle-aged women who are not pregnant or breastfeeding. The incidence rate accounts for about 4%-5% of benign breast diseases. Choose a simple mastectomy, which brings great pain to the patient

Method used

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  • Medicine composition for treating plasma cell mastitis and application of medicine composition

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preparation example Construction

[0047] The present invention also provides the preparation method of the above-mentioned pharmaceutical composition, comprising:

[0048] The first step is to take saponins, forsythia, artemisia annua, dandelion, bitter grass, ivy, four-leaf clover, toosendan, vitex and ingot, and mix them together with alcohol concentration of 70%. Extract with ~80% ethanol for 3 times, combine the extracts, concentrate to remove the solvent, grind them into powder, and set aside;

[0049] In the second step, the remaining components are mixed together, decocted with water for 3 times, the decoction liquid is combined, concentrated to remove water, crushed into powder, and set aside;

[0050] In the third step, the powder prepared in the first step is mixed with the powder prepared in the second step, and various auxiliary materials are added to prepare the required dosage form.

[0051] The first step is further specifically to take saponins, forsythia, artemisia annua, dandelion, bitter gr...

Embodiment 1

[0056] Embodiment 1 oral liquid 1

[0057] Take 20g of saponins, 30g of forsythia, 15g of Artemisia annua, 25g of dandelion, 15g of bitter grass, 15g of small ivy, 20g of four-leaf clover, 20g of toosendan, 15g of vitex leaves and 20g of ingot grass, and mix them together. Add 1 kg of ethanol with an alcohol concentration of 80%, heat and reflux for 2 hours, extract, and filter with an ultrafiltration membrane with a molecular weight of 20,000 Daltons to obtain the first extract, add 400 g of the obtained dregs with an alcohol concentration of 80% ethanol, heated to reflux for 45 minutes, extracted, and obtained the second extract by filtering with an ultrafiltration membrane with a molecular weight of 20,000 Daltons, combined the first extract and the second extract, concentrated under reduced pressure to remove the ethanol solvent, dried, and pulverized To make the first powder, take 25g of Radix Paeoniae Rubra, 30g of Rehmannia glutinosa, 20g of Sophora flavescens, 15g of B...

Embodiment 2

[0058] Embodiment 2 oral liquid 2

[0059] Take 15g of saponins, 25g of forsythia, 10g of Artemisia annua, 20g of dandelion, 10g of bitter grass, 10g of small ivy, 15g of four-leaf clover, 15g of toosendan, 10g of vitex leaves and 15g of ingot grass, and mix them together. Add 0.8 kg of ethanol with an alcohol concentration of 80%, heat and reflux for 2 hours, extract, and obtain the first extract by filtering with an ultrafiltration membrane with a molecular weight of 20,000 Daltons, and add 300 g of alcohol concentration of 80% to the dregs obtained by filtering. % ethanol, heated to reflux for 45 minutes, extracted, and obtained a second extract by ultrafiltration with a molecular weight of 20,000 Daltons, combined with the first extract and the second extract, concentrated under reduced pressure to remove the ethanol solvent, and dried. Grind into the first powder, take 20g of Radix Paeoniae Rubra, 25g of Rehmannia glutinosa, 15g of Sophora flavescens, 10g of Bupleurum, 10...

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Abstract

The invention provides medicine composition for treating plasma cell mastitis. The medicine composition comprises raw materials as follows: Chinese honeylocust spine, red paeony roots, prepared rehmannia roots, weeping forsythiae capsules, sweet wormwood herb, lightyellow sophora roots, Chinese thorowax roots, dandelion, herba of Ajuga pantantha Hand. Mazz., stems of cocculus orbiculatus, tamarix chinensis, bunge bedstraw herb, red garlic, Elaeagnus angustifolia, szechwan chinaberry fruits, bunge corydalis herb, hempleaf negundo chastetree leaves, leaves of downy rosemyrtle and hypericum sampsonii hance. The medicine composition has a good treatment effect on plasma cell mastitis, has little harm and is worth clinic popularization and application, and plasma cell mastitis cannot relapse.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating plasma cell mastitis and its application. Background technique [0002] Plasma cell mastitis was named as varicose tumor by Bloodgood in 1923. In 1925, Ewing found that the lesion was mainly infiltrated by a large number of plasma cells under the microscope, so it was called plasma cell mastitis. The disease is more common in multiparous women. The main clinical manifestations are nipple discharge and breast lumps. In addition, there may be breast pain, nipple inversion, local skin adhesions, and even orange peel-like changes. Studies at home and abroad have suggested that the incidence of plasma cell mastitis Related to autoimmunity, there is still no unified understanding of treatment. It mainly occurs in young and middle-aged women who are not pregnant or breastfeeding. The incidence rate accounts for about 4%-5% ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P15/14
Inventor 侯红李振凤方堃于玺
Owner QINGDAO CENT HOSPITAL
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