Medicine for treating wegener's granulomatosis combined orbital pseudotumor and preparation method thereof

A technology for Wegener's granulomatosis and drugs, applied in the field of medicine, can solve problems such as unreported

Inactive Publication Date: 2016-01-06
JINAN XINSHIDAI MEDICINE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] So far, there is no report that there is a specific drug f

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Amaranth 1000g, Myrobalan 500g, Hedyotis diffusa 1500g, Gushanlong 1500g, Tugua 200g, Yanzhou Selaginella 500g.

[0025] Preparation:

[0026] a. Add water to decoct Amaranthus, Myrobalan, Hedyotis diffusa, Gushanlong, Tugua, and Yanzhou Selaginella, and decoct them twice. Add 3 times the volume of the drug and decoct in water for 1.5 hours, combine the decoction, and filter; the filtrate is concentrated at 60°C to a concentrated solution with a relative density of 1.20-1.25, let it cool, add ethanol until the alcohol content reaches 75%, stir well, Stand at room temperature for 12 hours, filter; the filtrate is recovered at 60°C to recover ethanol and concentrate to a thick paste with a relative density of 1.30-1.35;

[0027] b. add honey and water to the thick paste prepared in step a to make ointment, and prepare 1000g altogether.

[0028] Usage and dosage: 50g each time, 2-3 times a day, 10 days as a course of treatment.

Embodiment 2

[0030] Amaranth 900g, Myrobalan 550g, Hedyotis diffusa 1400g, Gushanlong 1600g, Tugua 180g, Selaginella 550g.

[0031] Preparation:

[0032] a. Add water to decoct Amaranth, Myrobalan, Hedyotis diffusa, Gushanlong, Tugua, and Yanzhou Selaginella, and decoct them twice. Add 2 times the volume of the medicine and decoct in water for 1 hour, combine the decoction, and filter; the filtrate is concentrated at 60°C to a concentrated solution with a relative density of 1.20-1.25, let it cool, add ethanol until the alcohol content reaches 75%, stir well, Stand at room temperature for 12 hours, filter; the filtrate is recovered at 60°C to recover ethanol and concentrate to a thick paste with a relative density of 1.30-1.35;

[0033] b. Add honey and water to the thick paste prepared in step a to make granules, and prepare 1000g altogether.

[0034] Usage and dosage: 50g each time, 2-3 times a day, 10 days as a course of treatment.

Embodiment 3

[0036] Amaranth 1000g, Myrobalan 450g, Hedyotis diffusa 1600g, Gushanlong 1400g, Tugua 220g, Yanzhou Selaginella 450g.

[0037] Preparation:

[0038] a. Decoct Amaranthus amaranthus, Myrobalan, Hedyotis diffusa, Gushanlong, Tugua, and Yanzhou Selaginella with water and decoct for two times. For the first time, add 6 times the volume of the medicine and decoct for 2.5 hours. Add 5 times the volume of the drug and decoct in water for 2 hours, combine the decoction, and filter; the filtrate is concentrated at 60°C to a concentrated solution with a relative density of 1.20-1.25, let it cool, add ethanol until the alcohol content reaches 75%, stir well, Stand at room temperature for 12 hours, filter; the filtrate is recovered at 60°C to recover ethanol and concentrate to a thick paste with a relative density of 1.30-1.35;

[0039] b. add honey and water to the thick paste prepared in step a to make ointment, and prepare 1000g altogether.

[0040] Usage and dosage: 50g each time, ...

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PUM

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a medicine for treating a wegener's granulomatosis combined orbital pseudotumor and a preparation method thereof. The medicine for treating the medicine for treating a wegener's granulomatosis combined orbital pseudotumor is prepared from, by weight, 80-120 parts of amaranthaceae aerva sanguinolenta, 40-60 parts of fructus terminaliae billericae, 130-170 parts of oldenlandia diffusa, 130-170 parts of arcangelisia loureiri, 16-24 parts of tsuchiuri and 40-60 parts of selaginella involvens. The medicine is used for treating the wegener's granulomatosis combined orbital pseudotumor, and the total remission rate is 62%.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a medicine for treating Wegener's granulomatosis combined with intraorbital pseudotumor and a preparation method thereof. Background technique [0002] Wegener granulomatosis (WG) is a systemic, necrotizing, and granulomatous vasculitis involving small and medium blood vessels, with a typical triad of necrosis, granulomatous, and vasculitis, and various clinical manifestations , the typical triad is the lesions of the upper and lower respiratory tract and kidney; eye involvement is more common, 50%~60%, any area of ​​the eye can be involved, and 15%~20% can invade the orbit and manifest as exophthalmos, namely Intraorbital pseudotumor. If the cause of intraorbital pseudotumor cannot be identified early and the treatment is delayed, it may cause serious ocular complications, such as loss of vision and removal of the eyeball. . [0003] So far, there is no report th...

Claims

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Application Information

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IPC IPC(8): A61K36/748A61P9/14A61P27/02
Inventor 刘爱良
Owner JINAN XINSHIDAI MEDICINE SCI & TECH
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