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Egg yolk antibody microcapsule feed additive for preventing carassius auratus gibelio bacterial septicemia

A feed additive, heterogeneous gibel carp technology, applied in microcapsules, antibacterial drugs, antibodies, etc., can solve problems that are difficult to control, and achieve the effects of enhancing resistance, increasing economic benefits, and improving survival rate

Active Publication Date: 2015-12-23
YANGZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, it is difficult to control the occurrence and prevalence of diseases caused by three types of mesophilic Aeromonas mesophilic species, Aeromonas sobria, Aeromonas hydrophila and Aeromonas victorii, in the breeding and production of heterogeneous gibel crucian carp. Lack of an easy-to-use disease-resistant feed additive suitable for heterogeneous gibel carp

Method used

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  • Egg yolk antibody microcapsule feed additive for preventing carassius auratus gibelio bacterial septicemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1, a kind of yolk antibody microcapsule feed additive of anti-heterogenetic gibel carp bacterial sepsis, this additive is made of the following three kinds of raw materials of weight ratio:

[0030] (1) 80% yolk antibody freeze-dried powder against bacterial septicemia of heterogeneous gibel carp;

[0031] (2) Astragalus powder 12%;

[0032] (3) β-cyclodextrin 8%;

[0033] The steps of the preparation method of the described anti-heterogenetic gibel carp bacterial sepsis egg yolk antibody freeze-dried powder are as follows:

[0034] ① The pathogen Aeromonas temperatus ( Aeromonassobria ) JY081016-1, Aeromonas hydrophila ( Aeromonas hydrophila ) WJ11-3 and Aeromonas victoria ( Aeromonas veronii ) DF-1 strains were inoculated on ordinary nutrient broth medium, cultured on a shaker at 28-30°C for 24 hours, added formaldehyde with a final volume concentration of 0.3% at 28°C for 48 hours, and centrifuged to obtain inactivated bacteria;

[0035] ② Soak Astr...

Embodiment 2

[0038] Embodiment 2, a kind of yolk antibody microcapsule feed additive of anti-heterogenetic gibel carp bacterial sepsis, this additive is made of the following three kinds of raw materials of weight ratio:

[0039] (1) Freeze-dried powder of egg yolk antibody against gibel carp bacterial sepsis 83%;

[0040] (2) Astragalus powder 10.5%;

[0041] (3) β-cyclodextrin 5.5%;

[0042] The preparation method of the yolk antibody freeze-dried powder against bacterial septicemia of heterogeneous gibel carp is the same as that in Example 1.

Embodiment 3

[0043] Embodiment 3, a kind of yolk antibody microcapsule feed additive of anti-heterogenetic gibel carp bacterial sepsis, this additive is made of the following three kinds of raw materials of weight ratio:

[0044] (1) Freeze-dried powder of yolk antibody against bacterial septicemia of heterogeneous gibel crucian carp 85%;

[0045](2) Astragalus powder 10%;

[0046] (3) β-cyclodextrin 5;

[0047] The preparation method of the yolk antibody freeze-dried powder against bacterial septicemia of heterogeneous gibel carp is the same as that in Example 1.

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Abstract

The invention discloses an egg yolk antibody microcapsule feed additive for resisting carassius auratus gibelio bacterial septicemia. The additive consists of three kinds of raw materials, namely, egg yolk antibody freeze-dried powder for resisting the carassius auratus gibelio bacterial septicemia, astragalus powder and beta-cyclodextrin, wherein the egg yolk antibody freeze-dried powder for resisting the carassius auratus gibelio bacterial septicemia is mainly used for lowering the infection rate of carassius auratus gibelio by three kinds of mesophilic aeromonas or preventing carassius auratus gibelio from being infected by the three kinds of mesophilic aeromonas; the astragalus powder is used for enhancing the immunity of the carassius auratus gibelio; the beta-cyclodextrin is mainly used for realizing embedding and slow release of the egg yolk antibody freeze-dried powder. When the microcapsule feed additive and a commercially available carassius auratus gibelio compound feed are fed together according to a certain proportion, diseases caused by three kinds of pathogenic mesophilic aeromonas can be prevented and treated during cultivation of the carassius auratus gibelio, the yield of the carassius auratus gibelio is increased, and the economical benefit of carassius auratus gibelio cultivation is increased remarkably. The problem of bacterial septicemia in current carassius auratus gibelio production is solved.

Description

technical field [0001] The invention relates to a feed additive for aquaculture, in particular to a microcapsule feed additive for resisting bacterial sepsis of heterogeneous gibel crucian carp. Background technique [0002] Allogenetic gibel carp is an excellent variety obtained by distant hybridization of gibel carp from Fangzheng County, Heilongjiang as the female parent and red carp from Xingguo County, Jiangxi Province as the male parent. This species not only has delicious meat and rich nutrition, but also has a wide appetite and fast growth. It is currently one of the main species of freshwater aquaculture fish in my country. With the continuous expansion of its breeding scale and density, diseases often occur. Among them, three kinds of mesophilic Aeromonas mesophila, including Aeromonas temperatus, Aeromonas hydrophila and Aeromonas victoria, can cause sepsis in heterogeneous gibel carp, which seriously affects the breeding and production of heterogeneous gibel carp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/395A61K9/50A61P31/04A23K1/16
CPCY02A40/818
Inventor 张晓君高晓建毕可然安振华董小敬徐加涛
Owner YANGZHOU UNIV
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