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Traditional Chinese medicine composition having sleep improvement and immunity boost effects as well as preparation method and application of traditional Chinese medicine composition

A technology that enhances immunity and improves sleep. It is applied in drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas. It can solve problems such as unclear efficacy of melatonin in improving sleep, drug dependence, and large impact on the kidneys. Achieve the effect of rigorous medication, no toxic side effects, and less impurities

Active Publication Date: 2015-11-18
雷允上药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hypnotics commonly used clinically at present include benzodiazepines, barbiturates and other non-barbiturates. The effect of treating insomnia is relatively obvious, but it has a greater impact on the liver and kidney, and users are prone to drug reactions. Dependence, usually increasing the dosage of medicine to maintain the effect, but also produce a lot of toxic side effects, so it is not suitable for long-term use of drugs
The effect of melatonin on improving sleep is not yet clear. Long-term or high-dose melatonin may cause harm to the human body, such as significantly inhibiting the function of the human reproductive system

Method used

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  • Traditional Chinese medicine composition having sleep improvement and immunity boost effects as well as preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition having sleep improvement and immunity boost effects as well as preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition having sleep improvement and immunity boost effects as well as preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Chinese medicine composition oral liquid of the present invention

[0058] 1. Raw material parts by weight

[0059] Acanthopanax 2 parts, American ginseng 1 part, jujube seed 10 parts, Polygonatum 6 parts, psoraleae 3 parts, Poria cocos 10 parts.

[0060] 2. Preparation steps

[0061] (1) Get the American ginseng, Acanthopanax, and Psoraleae, add 50% ethanol (volume concentration) of 5 times the weight of the medicinal materials, heat and reflux to extract 2 times, each 2 hours, merge to obtain the alcohol extract; ethanol recovery ;

[0062] (2) Take the dregs extracted with ethanol in step (1) and add 10 times the amount of water, heat and decoct for 2 hours each time, and combine to obtain the water extract;

[0063] (3) Concentrate the alcohol extract to no ethanol smell, the equivalent of the medicinal material (relative to the alcohol extraction part) is about 1:1, the water extract is concentrated to the equivalent of about 0.8:1, mix with the alcohol extracti...

Embodiment 2

[0067] Chinese medicine composition granule of the present invention

[0068] 1. Raw material parts by weight

[0069] Acanthopanax 4 parts, American ginseng 2 parts, jujube seed 30 parts, Polygonatum 10 parts, psoraleae 8 parts, Poria cocos 30 parts.

[0070] 2. Preparation steps

[0071] (1) Take the above-mentioned American ginseng, Acanthopanax, and psoralen, add 60% ethanol in an amount 8 times the weight of the medicinal materials, heat and reflux for extraction twice, each time for 1 hour, and combine to obtain an alcohol extract; ethanol recovery;

[0072] (2) Take the dregs extracted with ethanol in step (1) and add 8 times the amount of water to Suanzaoren, Rhizoma Polygonatum and Poria Cocos, heat and decoct to extract 2 times, each time for 1 hour, and combine to obtain the water extract;

[0073] (3) Concentrate the alcoholic extract to no ethanol smell, the medicinal material equivalent (relative to the alcohol extraction part) is about 0.8:1, the water extract...

Embodiment 3

[0076] Chinese medicine composition capsule of the present invention

[0077] 1. Raw material parts by weight

[0078] Acanthopanax 4 parts, American ginseng 8 parts, jujube seed 20 parts, Polygonatum 16 parts, psoralen 2 parts, Poria cocos 10 parts.

[0079] 2. Preparation steps

[0080] (1) Take the above-mentioned American ginseng, Acanthopanax, and psoralen, add 80% ethanol in an amount 10 times the weight of the total medicinal materials, heat and reflux for extraction twice, each time for 2 hours, and combine to obtain an alcohol extract; ethanol recovery;

[0081] (2) Take the step (1) to extract the dregs of the medicine with ethanol, add 5 times the amount of water to the jujube seed, sealwort, and poria cocos, heat and extract 2 times, each time for 2 hours, and combine to obtain the water extract;

[0082] (3) Concentrate the ethanol extract until it has no ethanol smell, the medicinal material equivalent (relative to the alcohol extraction part) is about 1:1, the...

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PUM

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Abstract

The invention discloses traditional Chinese medicine composition having sleep improvement and immunity boost effects as well as a preparation method and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition having the sleep improvement and immunity boost effects is prepared from Siberian ginseng, American ginseng, semen ziziphi spinosae, polygonatum, psoralea corylifolia and wolfiporia extensa. Animal function test results prove that the provided traditional Chinese medicine composition has the sleep improvement and immunity boost effects; animal safety test results prove that the traditional Chinese medicine composition is safe and has no toxic and side effects and no teratogenic and mutagenic actions. Human feeding trials prove that the traditional Chinese medicine composition can effectively improve symptoms such as insomnia, low immunity and the like, has significant effect, can be used for preparing drugs or health care products and has broad market prospects.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions of medicines or health products, in particular to a traditional Chinese medicine composition capable of improving sleep and enhancing immunity, its preparation method and application. Background technique [0002] Sleep is a spontaneous and reversible resting state that occurs periodically in higher vertebrates, manifested as a decrease in the body's response to external stimuli and a temporary interruption of consciousness. About 1 / 3 of a person's life is spent in sleep. When people are in a sleep state, people's brains and bodies can be rested, rested and recovered, and an appropriate amount of sleep is helpful for people's daily work and study. Scientifically improving sleep quality is the guarantee for people's normal work, study and life. Sleep disorder refers to the abnormality of sleep quantity and sleep quality, or certain clinical symptoms occur during sleep, suc...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P37/04A61P25/20
Inventor 叶华王恒斌李全孙翔祝倩倩罗年翠王亦周
Owner 雷允上药业集团有限公司
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