Film-forming gel composition, application and wound protecting material

Abstract

The invention discloses a film-forming gel composition, its application and a wound protecting material. The film-forming gel composition comprises the following ingredients: hydroxy propyl cellulose, an esterifying agent, a cross-linking agent and a solvent, wherein the esterifying agent contains saturated fatty hydroxy carboxylic acid and tannic acid. The chemical general formula of the saturated fatty hydroxy carboxylic acid is CnH2n+2-m-L(OH)m(COOH)L, wherein n, m and L are integers; n is greater than or equal to 1; m is greater than or equal to 1; L is greater than or equal to 1; m+L is 2-5; and n+L is 2-6. The film-forming gel composition can be used to prepare a drug for treating skin or oral mucosal diseases, or can be used as a drug carrier to prepare a drug film-forming gel composition and a wound protecting material. The film-forming gel composition contains no aromatic organic carboxylic acid with pharmacological activity, will not produce pharmaceutical action on human body and also will not cause adverse reactions on human body.

Description

technical field [0001] The invention relates to a film-forming gel composition, its use and a wound-protecting material. Background technique [0002] Human skin is caused by cuts, abrasions, incisions, scalds, etc., or skin inflammation caused by bacteria, fungi or viruses, is a common disease that people often encounter in daily life. The general treatment measures are to clean the wound, stop bleeding, disinfect, and then use wound protection preparations to protect the wound surface and prevent infection. [0003] At present, most of the commonly used topical skin protection preparations are solid bandage-like "Band-Aid" products. This product is a long-shaped adhesive plaster composed of elastic textiles and adhesive plaster adhesives. The inner layer is attached with a strong absorbent It is a protective composite pad composed of a special absorbent pad and a layer of isolation permeable membrane. The absorbent pad has two types: drug-containing and drug-free, which h...

AI Technical Summary

Problems solved by technology

[0014] The technical problem to be solved by the present invention is to overcome the fact that the solid band-aid type wound-protecting preparations in the prior art are easy to cause secondary damage to the wound surface, accumulated water and scale, resulting in infection, limited use size, inability to adhere to the wound, poor flexibility, and inability to make the affected area To overcome the defects of the wetness of the liquid band-aids in the prior art, they are poor in air permeability, easy to cause stuffy, itching, dampness, allergies and other adverse side effects, or they are not hydrophobic, have poor mechanical strength and flexibility, and are difficult to completely peel off , easy to stick to dust and the adhesion between the film and the skin is not tight enough, poor wear resistance, easy to be erased, etc., and to overcome some film-forming gel compositions mostly use aromatic organic carboxylic acids with pharmacological activity as esterification agents, which is inevitable It exists in the film-forming gel composition in a free state, thereby producing pharmacological effects on the human body and causing adverse reactions. A film-forming gel composition, its use, and wound-protecting materials are provided.

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