Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Compound skin cream for treating leucoderma

A vitiligo and ointment technology, applied in the field of external medicines, can solve problems such as not very good treatment effect, achieve good stability and no irritation, increase the content of anisodamine, and achieve the effects of good treatment effect

Inactive Publication Date: 2015-10-28
魏传梅
View PDF1 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is known that more than 100 kinds of Chinese herbal medicines contain quercetin, and the traditional Chinese medicine Cuscuta containing quercetin is often used as an external preparation for the treatment of vitiligo. These external preparations can relieve the pain of patients during the treatment process and have fewer toxic and side effects. However, The treatment effect is not very good

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Compound skin cream for treating leucoderma
  • Compound skin cream for treating leucoderma
  • Compound skin cream for treating leucoderma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Weigh 12g of sodium lauryl sulfate, 50g of glycerin, 0.5g of ethylparaben, 50g of propylene glycol, and an appropriate amount of purified water to make 1000g, 200g of white petrolatum, 100g of liquid paraffin, and 50g of glyceryl monostearate according to the ratio of raw materials. , stearyl alcohol 50g, anisodamine 2g, 1mol / L hydrochloric acid 10g, 8-methoxypsoralen (8-MOP) 0.5g, dimethylsulfoxide 15g, quercetin 1g, betamethasone 1g.

[0065] The preparation method is:

[0066] (1) Weigh white petrolatum, liquid paraffin, stearyl alcohol, and glyceryl monostearate according to the above prescription, heat and melt in a water bath at 80°C to form an oil phase, keep warm at 80°C for later use, and obtain A.

[0067] (2) Weigh sodium lauryl sulfate, glycerin, propylene glycol, ethylparaben and an appropriate amount of purified water according to the above prescription, heat and dissolve into the water phase, keep warm at 80°C for later use, and obtain B.

[0068] (3) We...

Embodiment 2

[0072] Weigh 10g of sodium lauryl sulfate, 60g of glycerin, 0.8g of ethylparaben, 60g of propylene glycol, and an appropriate amount of purified water to make 1000g, 210g of white petrolatum, 110g of liquid paraffin, and 70g of glyceryl monostearate according to the ratio of raw materials. , stearyl alcohol 70g, anisodamine 3g, 1mol / L hydrochloric acid 17g, 8-methoxypsoralen (8-MOP) 0.8g, dimethylsulfoxide 24g, quercetin 3g, betamethasone 1.2g .

[0073] The preparation method is:

[0074] (1) Weigh white petrolatum, liquid paraffin, stearyl alcohol, and glyceryl monostearate according to the above prescription, heat and melt in a water bath at 80°C to form an oil phase, keep warm at 80°C for later use, and obtain A.

[0075] (2) Weigh sodium lauryl sulfate, glycerin, propylene glycol, ethylparaben and an appropriate amount of purified water according to the above prescription, heat and dissolve into the water phase, keep warm at 80°C for later use, and obtain B.

[0076] (3...

Embodiment 3

[0080] Weigh 12g of sodium lauryl sulfate, 100g of glycerin, 1.0g of ethylparaben, 100g of propylene glycol, 1000g of purified water, 250g of white petrolatum, 150g of liquid paraffin, and 90g of glyceryl monostearate according to the ratio of raw materials. , stearyl alcohol 90g, anisodamine 5.0g, 1mol / L hydrochloric acid 25g, 8-methoxypsoralen (8-MOP) 1.0g, dimethyl sulfoxide 30g, quercetin 5.0g, betamethasone 1.5g.

[0081] The preparation method is:

[0082] (1) Weigh white petrolatum, liquid paraffin, stearyl alcohol, and glyceryl monostearate according to the above prescription, heat and melt in a water bath at 80°C to form an oil phase, keep warm at 80°C for later use, and obtain A.

[0083] (2) Weigh sodium lauryl sulfate, glycerin, propylene glycol, ethylparaben and an appropriate amount of purified water according to the above prescription, heat and dissolve into the water phase, keep warm at 80°C for later use, and obtain B.

[0084] (3) Weigh anisodamine in an ap...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
recovery rateaaaaaaaaaa
Login to View More

Abstract

The invention relates to an externally-used drug used for treating leucoderma skin disease, in particular to compound skin cream for treating leucoderma. The cream comprises, by weight, 0.20-0.50% of anisodamine, 0.10-0.50% of quercetin and 0.10-0.15% of betamethasone, the cream further comprises, by weight, 1.50-3.00% of dimethyl sulfoxide and 0.05-0.10% of 8-methoxypsoralen, and the cream further comprises oil phase raw materials, namely 15.00-25.00% of albolene, 8.00-15.00% of liquid paraffin, 5.00-9.00% of glycerin monostearate and 5.00-9.00% of octadecanol, and water phase raw materials, namely 0.50-1.20% of lauryl sodium sulfate, 5.00-10.00% of glycerinum, 0.05-0.10% of ethylparaben and 5.00-10.00% of propylene glycol; the cream further comprises 1.00-2.50% of hydrochloric acid and purified water, and the pH value ranges from 5.5 to 6.5. According to the compound skin cream for treating leucoderma, the formula is reasonable, the technique is feasible, and the cream has the advantages of being great in stability, good in effect and free of irritation.

Description

technical field [0001] The invention relates to a medicine for external use for treating vitiligo skin disease, in particular to a compound skin cream for treating vitiligo. Background technique [0002] Vitiligo is a common acquired localized or generalized skin depigmentation disease. Caused by the loss of skin melanocyte function, the etiology is unknown, and it may be related to genetics, autoimmunity, self-destruction of melanocytes, lack of trace elements, and psychoneurochemical factors. Vitiligo can occur at all ages. Although vitiligo does not affect health, when it occurs on exposed parts such as the face and neck, it will seriously affect the appearance and easily cause mental or psychological pain to patients. Because the cause of the disease is not clear, easy to diagnose and difficult to treat, it is a major difficult disease in the field of dermatology today. [0003] Today, the main methods of treating vitiligo are: ultraviolet radiation, taking photosensit...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/573A61K9/06A61P17/10A61P29/00A61P17/18A61P17/00A61K31/46A61K31/352
Inventor 魏传梅
Owner 魏传梅
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com