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A low-pressure chamber for experimental animals used for high-altitude medical research and a pressure control method based on the low-pressure chamber

A technology for experimental animals and low-pressure chambers, applied in non-electric variable control, chemical instruments and methods, laboratory appliances, etc., can solve problems such as accumulation of gas pollutants, distortion of experimental results, and impact on the health of experimental animals

Active Publication Date: 2017-03-29
华夏富康环境科技有限公司
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  • Application Information

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Problems solved by technology

This will cause the experimental animals to be in a state of hypoxia, and will also accumulate gas pollutants emitted by animals such as carbon dioxide, ammonia, and hydrogen sulfide in the cabin, which will seriously affect the health of the experimental animals and cause distortion of the experimental results.

Method used

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  • A low-pressure chamber for experimental animals used for high-altitude medical research and a pressure control method based on the low-pressure chamber
  • A low-pressure chamber for experimental animals used for high-altitude medical research and a pressure control method based on the low-pressure chamber
  • A low-pressure chamber for experimental animals used for high-altitude medical research and a pressure control method based on the low-pressure chamber

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[0064] In the working cabin volume is 0.6m 3 In the cabin, 20 rats and 40 mice were placed, and the equipment was operated for 23 hours a day, and the bedding was replaced or water was added in the remaining 1 hour. The effects of the present invention were examined.

[0065] (1) In the maintenance phase, the maximum negative fluctuation of altitude is -50 meters, and the maximum positive fluctuation is +45 meters;

[0066] (2) The error of the altitude measured and calculated within the range of working pressure (2000 meters above sea level to 9000 meters above sea level) in the cabin is less than 1%;

[0067] (3) At an altitude of 5,500 meters, the measured air exchange rate in the cabin is 15.5 times per hour, and at an altitude of 9,000 meters, the air exchange rate is 10.4 times per hour;

[0068] (4) Set the rise / fall time to 30 minutes, and the measured result is 30.24±0.89 minutes;

[0069] (5) The measured working noise is 50 decibels;

[0070] (6) After 23 hours ...

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Abstract

The present invention discloses an experimental animal low-pressure cabin for plateau medicine research, and a pressure control method based on the experimental animal low-pressure cabin, and belongs to the technical field of medical scientific research instrument equipment. The experimental animal low-pressure cabin comprises a work cabinet and an electrical cabinet arranged on the bottom portion of the work cabinet, wherein the work cabinet adopts the full transparent design so as to easily meet the illumination requirements of the experimental animals and make the laboratory personnel easily perform real time observation on the experimental animals, a gas inlet pipe extending into the work cabinet and a gas discharge pipe extending into the work cabinet are arranged inside the electrical cabin, the gas inlet pipe and the gas discharge pipe are respectively provided with an electrically controlled proportional valve and a diaphragm vacuum pump, an electrical program control system is further arranged inside the electrical cabinet, and a PLC controller adjusts the dynamic balance between the gas complementing amount and the gas exhaust amount by controlling the opening degree of the electrically controlled proportional valve and the opening of the diaphragm vacuum pump so as to make the altitude fluctuation be maintained at a certain level. According to the present invention, the air pressure control way used by the control method of the present invention is unique, the fluctuation range is small, the accuracy is high, and the number of the gas exchange can be ensured.

Description

technical field [0001] The invention belongs to the technical field of medical scientific research instruments and equipment, and relates to an experimental animal hypobaric chamber, in particular to an experimental animal hypobaric chamber used for plateau medical research and a pressure control method based on the hypobaric chamber. Background technique [0002] In recent years, the level of altitude medical research at home and abroad has continued to expand. Due to the limited conditions of on-site research, most scientific research is carried out in laboratories in non-altitude areas, providing a hypobaric chamber that can replicate experimental animal models of altitude sickness , is a necessary condition for this study. There is no mature and commercialized hypobaric chamber for experimental animals at home and abroad. At present, such equipment is generally designed and manufactured by researchers themselves, and there are various degrees of defects. It is mainly re...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L1/00G05D27/02G01N33/00
Inventor 刘毅王东光康生汝颖
Owner 华夏富康环境科技有限公司
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