Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Natural pharmaceutical composition capable of preventing and treating alcoholic liver injury and preparation method

A technology of alcoholic liver injury and natural medicine, which is applied in the field of medicine to achieve the effect of promoting scavenging, eliminating excessive free radicals, and hindering the formation of lipid peroxide

Active Publication Date: 2015-09-16
JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT
View PDF2 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no ideal drug to effectively prevent and treat the occurrence and development of liver diseases in clinical practice.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Natural pharmaceutical composition capable of preventing and treating alcoholic liver injury and preparation method
  • Natural pharmaceutical composition capable of preventing and treating alcoholic liver injury and preparation method
  • Natural pharmaceutical composition capable of preventing and treating alcoholic liver injury and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1, Preparation of total triterpene acids from loquat leaves

[0050] (1) Loquat leaves 5kg, decocted with 10 times the amount of water to extract twice, each time for 2 hours, filtered, combined the filtrate for later use; dregs were extracted twice with 6 times the amount of 80% ethanol, each time for 2 hours, filtered, Combine the filtrates, add 400g of medicinal activated carbon, stir, filter, and recover ethanol from the filtrate, concentrate, filter, and dry the filter cake to obtain the total triterpene acids of loquat leaves.

Embodiment 2

[0051] Example 2 , Preparation of total flavonoids from loquat leaves

[0052] (2) Concentrate the water extract of loquat leaves to 7500ml, pass through the pre-treated AB-8 macroporous resin column, elute with deionized water for 4 times the column volume, discard the eluent, and then wash with 60% ethanol Remove 5 times the column volume, collect the eluate, recover ethanol, and dry to obtain the total flavonoids of loquat leaves.

Embodiment 3

[0053] Example 3 , Preparation of total flavonoids from loquat leaves 5 kg of grape leaves, reflux extraction with 8 times the amount of 60% ethanol for 2 times, each time for 3 hours, filtered, the filtrate recovered ethanol, concentrated to 7500ml, passed through the pre-treated AB-8 macroporous resin column, first used to remove Elute with deionized water for 5 times the column volume, discard the eluent, then elute with 10% ethanol for 3 times the column volume, discard the eluent, and then elute with 65% ethanol for 4 times the column volume, collect the eluate, Recover the ethanol and dry it to obtain the total flavonoids of the Serpentis japonicus.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a natural pharmaceutical composition capable of alcoholism prevention and liver protection. The composition is composed of loquat leaf total triterpenoid acid, loquat leaf total flavonoids, Ampelopsis grossedentata total flavonoids and a stigma maydis extract. The invention also relates to applications in preparing health foods capable of preventing and treating acute and chronic alcoholic liver injuries and health foods or drinks capable of treating non-alcoholic fatty liver diseases by the composition. Components of the composition of the invention generate good collaboration, treatment effects are obvious, raw materials are easy to obtain, the cost is relatively low, and practicability is strong.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a composition with natural products for preventing and treating alcoholic liver injury and other related diseases. Background technique [0002] Alcoholic liver damage (ALD) is a toxic liver disease caused by long-term excessive drinking, ALD is a Western nation The leading cause of liver cirrhosis in patients. In my country, alcoholic liver disease has gradually increased in recent years, and has become the second largest cause of liver disease after viral hepatitis. [0003] Alcoholic liver disease is a liver disease caused by long-term heavy drinking. It usually manifests as fatty liver at the initial stage, and then can develop into alcoholic hepatitis, alcoholic liver fibrosis and alcoholic cirrhosis. Severe alcoholism can induce extensive liver cell necrosis or even Liver failure. Up to now, there is no ideal medicine to effectively prevent and treat the occurrence an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/899A23L1/29A23L2/38A23F3/34A23G3/48A61P1/16
Inventor 胡铭南敏伦郝玉芳候宝王连萍赵宝琴赵全成
Owner JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com