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Triamcinolone acetonide and neomycin paste and preparation method thereof

A technology of triamcinolone acetonide acetate and neomycin, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, inorganic active ingredients, etc., can solve problems such as unstable product performance, complicated preparation process, and ineffective efficacy, and achieve Low cost, simple preparation process, and obvious drug efficacy

Inactive Publication Date: 2015-09-09
吉林万通药业集团郑州万通复升药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In view of the above-mentioned deficiencies in the prior art, the object of the present invention is to provide a triamcinolone acetonide neomycin plaster and a preparation method thereof, aiming at solving the problems of inconspicuous efficacy, unstable product performance, and preparation of the existing triamcinolone acetonide neomycin drug. Problems such as complex process and many processes

Method used

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preparation example Construction

[0066] A kind of preparation method of triamcinolone acetonide neomycin plaster as above, wherein, comprise steps:

[0067] A. Mixing: heat the three materials of lanolin, yellow vaseline and liquid paraffin to make them co-dissolve, and prepare the mixed oil medicinal material;

[0068] B. Foam rubber: Cut the rubber into strips, put it on the rubber mixing machine to break the rubber, and simultaneously immerse it in the above-mentioned oily medicinal material, so that the oily medicinal material is attached to the rubber surface evenly to obtain the foamed rubber, and then stand still for 15~ 72 hours, standby;

[0069] C. Kneading: Put the foamed rubber in a kneader for 50-60 minutes, then add thymol, triamcinolone acetate, neomycin sulfate, lithopone, zinc oxide and rosin to the kneader successively After mixing for 50-60 minutes, stand still for 15-72 hours and set aside;

[0070] D. Rough refining: take the mixed rubber material for rough refining;

[0071] E. Refini...

Embodiment 1

[0078] Thymol 8g;

[0079] Triamcinolone acetonide acetate 1 g;

[0080] Neomycin sulfate 8 g;

[0081] Rubber 280.17 g;

[0082] Rosin 129.31 g;

[0083] Yellow Vaseline 21.55 g;

[0084] Lanolin 12.93 g;

[0085] Liquid paraffin 4.31 g;

[0086] Lithopone 353.45 g;

[0087] Zinc Oxide 179.1 g.

Embodiment 2

[0089] Thymol 6g;

[0090] Triamcinolone acetonide acetate 1.5 g;

[0091] Neomycin sulfate 10g;

[0092] Rubber 260g;

[0093] Rosin 135g;

[0094] Yellow Vaseline 20g;

[0095] Lanolin 15 g;

[0096] Liquid paraffin 5 g;

[0097] Lithopone 350 g;

[0098] Zinc Oxide 180 g.

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Abstract

The invention discloses a triamcinolone acetonide and neomycin paste and a preparation method thereof. The triamcinolone acetonide and neomycin paste comprises the following components in parts by weight: 6-10 parts of thymol crystals, 0.5-1.5 parts of triamcinolone acetonide acetate, 6-10 parts of neomycin sulfate, 260-300 parts of rubber, 125-135 parts of rosin, 20-25 parts of yellow soft paraffin, 10-15 parts of wool fat, 3-5 parts of liquid paraffin, 350-360 parts of lithopone, and 175-180 parts of zinc oxide. According to the invention, the preparation process of the triamcinolone acetonide and neomycin paste is simple, the procedures are few, the cost is low, the medicine efficacy is obvious, and the performance is stable.

Description

technical field [0001] The invention relates to the field of medicaments, in particular to a triamcinolone acetonide neomycin patch and a preparation method thereof. Background technique [0002] Eczema is a skin inflammatory reaction caused by complex internal and external factors. Chronic eczema is generally limited and has infiltration and hypertrophy, severe itching, and easy recurrence. The etiology of the disease is complex, and internal and external factors interact, often in many ways. Patients often have allergic constitution, which is related to genetic factors, so it occurs in specific groups of people. [0003] Common internal factors such as: gastrointestinal dysfunction, mental stress, nervous dysfunction, endocrine disorders, infection lesions in the body, intestinal parasites, etc. [0004] External factors such as: sunlight, wind, cold, heat, scratching, friction and contact with soap, cosmetics, etc., animal fur, plants, chemical substances, etc. can als...

Claims

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Application Information

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IPC IPC(8): A61K35/36A61K9/70A61P17/00A61K31/05A61K33/30A61K31/58
Inventor 潘首德
Owner 吉林万通药业集团郑州万通复升药业股份有限公司
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