Multi-channel wireless closed loop deep brain neural sensing and control system

Abstract

Disclosed is a multi-channel wireless closed loop deep brain neural sensing and control system, which has three operating modes. In the first open-loop operating mode, acquired signals are saved through an SD card and are transmitted in real time to an upper computer through a wireless communication device, and electric pulse stimulation parameters of an outboard closed loop deep brain stimulation system are manually controlled. In the second closed loop operating mode, the acquired signals are automatically adjusted in real time to the output electric pulse stimulation parameters; and the acquired signals are stored through the SD card, or transmitted to the upper computer in real time. In the third closed loop operating mode, the acquired signals are stored through the SD card for offline analysis, and are meanwhile transmitted to the upper computer in real time; and the upper computer conducts closed loop algorithm computation of data of the signals, and controls the electric pulse stimulation parameters of the outboard closed loop deep brain stimulation system. The multi-channel wireless closed loop deep brain neural sensing and control system can be used as a temporary stimulator in a DBS surgery or as a research tool for obtaining clinical trial data, and a solution can be adjusted through recording and analyzing the effects of neural control.

Description

technical field [0001] The invention relates to a deep brain nerve perception control system, in particular to an external multi-channel wireless closed-loop deep brain electrical stimulation instrument. Background technique [0002] Deep brain stimulation (DBS) has been developed as an alternative to conventional ablative procedures commonly used in stereotaxic functional neurosurgery. DBS has been proved to be an effective method, because it has the characteristics of reversibility and adjustability, which greatly reduces the morbidity rate of the operation. Deep brain stimulation technology has a good effect in the treatment of neurological and mental diseases such as Parkinson's, pain, depression, obsessive-compulsive disorder, epilepsy, drug addiction and senile dementia. figure 2 Shows the appearance structure of the Medtronic 3628 temporary electrical stimulator, attached image 3 It shows the way of connecting electrodes. Electrical stimulation has been widely use...

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the deficiencies of the prior art, the purpose of the present invention is to provide a plug-in multi-channel wireless closed-loop deep brain nerve perception control system based on deep brain stimulation technology, aiming at realizing the wireless real-time display of the deep brain collected by the host computer PC terminal. At the same time as the field potential signal, the collected data can be immediately stored on the SD card of the electrical stimulation instrument for offline analysis, and can be manually adjusted online, or real-time adjusted by a closed-loop real-time algorithm, or automatically adjusted in real time after calculation by an embedded algorithm. Solve the problems that the existing technology cannot realize real-time electrical stimulation, and cannot flexibly provide personalized closed-loop control feedback control for patients

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