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Bacterial drug resistance quick projection system and method

A prediction system and prediction method technology, applied in the field of environment and public health, can solve the problems of isolation of measurement data, difficult data sharing, inability to establish long-term and effective drug resistance strain epidemic files, etc., to achieve the effect of reducing the speed and eliminating differences.

Active Publication Date: 2015-08-26
杨亮
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the data after each measurement of the traditional bacterial resistance test is only used as a current reference, and it is not easy to view and trace the data, and it is also impossible to establish a long-term and effective epidemic file of drug-resistant strains; and the measurement data is isolated, and the data is usually difficult to be used by different hospitals. share between
[0004] Due to the high mutation rate of bacterial genomes, the characteristics and drug resistance of individual bacterial genomes determined by traditional methods are often very unstable, making it difficult for medical staff to prescribe appropriate antibiotics based on previous experience even for the same bacteria

Method used

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  • Bacterial drug resistance quick projection system and method
  • Bacterial drug resistance quick projection system and method
  • Bacterial drug resistance quick projection system and method

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Embodiment 1

[0045] The present invention will be further described in detail below in conjunction with the embodiments and the accompanying drawings, but the embodiments of the present invention are not limited thereto.

[0046] Such as figure 1 As shown, the bacterial drug resistance rapid prediction system of this embodiment includes bacterial genome DNA extraction equipment, bacterial genome fingerprint typing equipment, intelligent terminals, cloud servers and bacterial database servers, and the bacterial genome DNA extraction equipment and bacterial genome fingerprint typing equipment Type equipment is connected, and described bacteria genome fingerprint typing equipment passes line (as USB, serial port UART, bus line SPI, I 2 C, etc.) or wireless signals (such as WIFI, Bluetooth, etc.) 4GLTE, etc.) are connected to the cloud server, and the cloud server is encrypted with the bacteria database server, and the bacteria database server internally encrypts and stores the biological chara...

Embodiment 2

[0120] Such as figure 1 and Figure 5 As shown, the software flow of the bacterial resistance rapid prediction system of the present embodiment is implemented through the following steps:

[0121] A. The user will obtain a sample of the bacterial genomic DNA to be tested in the bacterial genomic DNA extraction equipment;

[0122] B. The user places the DNA sample in the gel electrophoresis module of the bacterial genome fingerprint typing device to generate a strip-shaped fingerprint and the signal is collected by the image collector;

[0123] C. The user places the DNA sample in the DNA microarray module of the bacterial genome fingerprint typing device to generate a microarray-shaped fingerprint and the signal is collected by the image collector;

[0124] D. The user passes the DNA collected by the bacterial genome fingerprint typing device through the line (such as USB, serial port UART, bus SPI, I 2 C, etc.) or wireless signals (such as WIFI, Bluetooth, etc.) are sent t...

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Abstract

The invention discloses a bacterial drug resistance quick projection system and method. The system comprises bacteria genome DNA extracting equipment, bacteria genome fingerprint typing equipment, an intelligent terminal, a cloud server and a bacteria database server, wherein the bacteria genome DNA extracting equipment and the bacteria genome fingerprint typing equipment are connected; the intelligent terminal is connected with the cloud server through internet; the cloud server is further connected with the bacteria database server. The system and the method utilize technologies of internet and safe cloud computing storage, can be applied to not only antibiotic drug resistance spectrum prediction of clinical separation bacterial strains, but also antibiotic drug resistance spectrum prediction of environment separation bacterial strains, are beneficial to guidance of accurate antibiotic use of specialists, reduce the drug resistance gene spreading speed, and can also be an information platform of a bacterial drug resistance monitoring network.

Description

technical field [0001] The invention relates to a bacterial drug resistance prediction system, in particular to a bacterial drug resistance rapid prediction system and a prediction method thereof, belonging to the fields of environment and public health. Background technique [0002] At present, the detection of bacterial drug resistance is mainly divided into two categories: the first category uses culture technology to culture bacteria in solid or liquid media containing different antibiotics and directly observe the inhibition of antibiotics on bacterial growth, because bacterial culture is prone to failure. Contamination generally takes 24 hours or more to detect growth, and each antibiotic must be added to the medium separately (adding two or more antibiotics at the same time may produce synergistic or antagonistic effects), so multiple cultures are required to determine A strain is resistant to multiple antibiotics, so this traditional method has great limitations; the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/34C12Q1/68
CPCC12Q1/6806C12Q2537/165
Inventor 杨亮陈军
Owner 杨亮
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