A kind of medical suture and preparation method thereof

A suture and tendon technology, applied in medical science, surgery, surgical instruments, etc., can solve the problems of scars and subcutaneous lumps, poor elimination of immunogenicity, and poor virus inactivation effect, achieving no scar formation and fatality. Low resistance, good absorption effect

Active Publication Date: 2016-06-01
湖南然元医用高科技蛋白线有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The existing medical animal tendon sutures often cause inflammation, related diseases, scars and subcutaneous lumps in patients due to poor immunogenicity elimination and poor virus inactivation effects.

Method used

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  • A kind of medical suture and preparation method thereof
  • A kind of medical suture and preparation method thereof
  • A kind of medical suture and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0031] Medical sutures 1-5 were prepared according to the composition of treatment solutions 1-3 given in Table 1.

[0032] Firstly, extract the tendon from the tail of nutria and clean it; soak the freshly extracted tendon in treatment solution 1 at 35°C for 1.5h to obtain tendon raw material 1; soak tendon raw material 1 in treatment solution 2 for 1.5h at 35°C to obtain tendon Raw material 2; soak tendon raw material 2 in treatment solution 3 at 25°C for 45min to obtain tendon raw material 3; at 25°C, tendon raw material 3 (content 0.45mg / L, air pressure 0.1MPa) O 3 Contact 45min to obtain tendon raw material 4; soak tendon raw material 4 in medical alcohol at 25°C for 24 hours to cure to obtain tendon raw material 5; in a 100,000-level purification workshop, the temperature is 18-28°C and the humidity is 45-65%. Under certain conditions, tendon raw material 5 is air-dried, polished and typed, equipped with medical suture needles and packaged; finally, it is sterilized unde...

Embodiment 6

[0036] A medical suture was prepared by the same method as in Example 1, except that no acetic acid was added to the treatment liquid 1 to obtain a medical suture 6 .

Embodiment 7

[0038] The same method as in Example 1 was used to prepare medical sutures, the only difference being that in the treatment solution 2, NaCO was not added. 3 Ingredient, obtain medical suture 7.

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PUM

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Abstract

The invention provides a preparation method of a medical suture line. The preparation method of the medical suture line comprises the following steps: step 1, contacting freshly extracted animal muscle tendon with a treating fluid 1 at 30-40 DEG C for 1-2 h to obtain a muscle tendon raw material 1; step 2, contacting the muscle tendon raw material 1 with a treating fluid 2 at 30-40 DEG C for 1-2 h to obtain a muscle tendon raw material 2; step 3, contacting the muscle tendon raw material 2 with a treating fluid 3 at 15-30 DEG C for 0.5-1 h to obtain a muscle tendon raw material 3; step 4, contacting the muscle tendon raw material 3 with O3 at 15-30 DEG C for 0.5-1 h to obtain a muscle tendon raw material 4; step 5, contacting the muscle tendon raw material 4 with medicinal alcohol at 15-30 DEG C for 20-30 h for curing so as to obtain a muscle tendon raw material 5, wherein the components of the treating fluid 1 are pepsase and / or acetic acid; the components of the treating fluid 2 are trypsase and / or NaCO3; and the components of the treating fluid 3 are NaClO and / or NaOH. The medical suture line prepared by using the method has the advantages of high intensity, high absorption effect, low lethality and high safety.

Description

technical field [0001] The invention relates to the field of medical material processing, in particular to a medical suture and a preparation method thereof. Background technique [0002] Medical suture is a kind of thread material used for human surgical suture. From the perspective of material development, its development history has gone through: silk thread, catgut, chemical synthesis thread, and pure natural collagen suture; from the perspective of absorbability, Experienced: non-absorbable sutures and absorbable sutures; divided into natural sutures and artificial sutures according to the source of raw materials. [0003] The animal tendon suture made of animal tendon material is a pure natural absorbable suture, which is taken from animal tendon tissue and has many characteristics of collagen material. Compared with other sutures, it has good absorption effect, strong pulling force, and fast Unique functions such as wound healing are widely used in the medical suture...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L17/08A61L17/14
Inventor 刘权威杨一诚佘爱军
Owner 湖南然元医用高科技蛋白线有限公司
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