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Method for extracting silymarin by using food-grade ethanol as an extracting solvent

A technology for extracting solvents and silymarin, which is applied in organic chemistry and other fields, and can solve problems such as blank preparation methods

Active Publication Date: 2015-05-27
辽宁沃德药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The technical effect that this new process solves by eliminating certain chemicals from an extraction agent used during production or processing it's use. This makes it possible to make some types of nutrients like silymeerin inside meals without containing any harmful substances found on their ownerself.

Problems solved by technology

This patented technical problem addressed in this patents relates to finding ways to produce pure yarrow seed oil (YL) without containing harmful ingredients like Silymeerae Benthispidium Seabrightness Stabilizing Forsythaginaceae Boletus Anibe varies among different plants grown throughout Western Hemisphere countries including India. Existing methods involve collecting crude oils obtained through traditional techniques involving burning roots collected during harvesting operations on land near sources where water supply may be limited due to environmental concerns associated therewith. Therefore, new solutions must address issues related to current extractions technologies while maintain their safety features.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1, Laboratory Extraction (Small Experiment).

[0023] (1) Use a screw oil press to extract most of the oil from the air-dried and air-dried milk thistle seeds, and put 500 grams of cake powder into a Soxhlet extractor.

[0024] (2) It is connected to the whole set of Soxhlet extractor and adopts the electric heating mantle heating system.

[0025] (3) Inject 1500-2000ml of food-grade ethanol from the top of the cooling tube of the Soxhlet extractor, and inject the ethanol through the cake powder (material layer) into the round bottom flask at the bottom (pumice is added in the flask to prevent bumping).

[0026] (4) Turn the control knob of the electric heating mantle, adjust the heating electric power, and increase the temperature slowly until the ethanol in the flask boils. At this time, ethanol vapor rises to the top cooler and begins to trickle into the material layer, and the time is started.

[0027] (5) Extract for 16 hours. After the last reflux is comp...

Embodiment

[0029] Embodiment 2, workshop-level production example.

[0030] (1) The oil extraction treatment of milk thistle seeds is as in Example 1.

[0031] (2) Take 1000kg of milk thistle cake powder and put it into a 1.3 cubic meter multifunctional extraction tank.

[0032] (3) Inject an appropriate amount of food-grade ethanol 1800kg from the liquid injection pipe on the top of the extraction tank, and the liquid level is higher than the upper edge of the material layer.

[0033] (4) Static immersion for 4 hours, open the liquid discharge valves on the top and bottom of the extraction tank, put the extract solution impregnated with cake powder into the evaporation tank at a certain flow rate, and at the same time, fresh solvent is drawn from the injection pipe on the top of the extraction tank to the tank The same flow rate of the bottom discharge liquid is injected into the material layer in the tank, so that the solvent entering and flowing out reaches a dynamic balance, and the...

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PUM

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Abstract

The invention provides a method for extracting silymarin by using food-grade ethanol as an extracting solvent. The method is characterized by comprising the following steps: (1) removing fatty oil from silybum marianum seeds; (2) grinding oil-pressed cake, and putting into an extraction tank; (3) injecting a proper amount of food-grade ethanol from the top end of the extraction tank; (4) putting an extracting solution which is immersed with cake powder into an evaporation tank after static immersion, and injecting a fresh solvent into the charge layer in the extraction tank from the top end of the extraction tank to dynamically balance solvents flowing in and out of the extraction tank; (5) dynamically extracting; (6) concentrating; (7) stopping concentrating until the density is 1.2g/ml, and transferring fluid extract obtained by concentration into an extract washing machine; (8) degreasing for the second time; (9) baking; (10) grinding, and screening products with different specifications for users. According to the method, food-grade ethanol is used as an extracting agent instead of chemical raw materials in the prior art, so that obstacles in the march of silymarin forward to the field of health foods are cleared.

Description

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Claims

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Application Information

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Owner 辽宁沃德药业有限公司
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