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Traditional Chinese medicinal preparation for treating hypertension and preparation method thereof

A traditional Chinese medicine preparation and high blood pressure technology, which is applied in the field of pharmacy, can solve the problems of rare high blood pressure, achieve quick results, simple preparation process, and improve the effect of blood hypercoagulability

Inactive Publication Date: 2015-05-20
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are very few traditional Chinese medicines for the treatment of hypertension on the market.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] S11. Take 15 parts of coreopsis, crush them into coarse particles, and use 75% ethanol to reflux extract 3 times according to the ratio of material to liquid ratio of 1:8, each time for 3 hours, combine the extracts of 3 times, concentrate and recover under reduced pressure After the solvent, add chloroform for extraction at a ratio of 1:1, then add ethyl acetate for extraction at a ratio of 1:1, combine the two extracts, and concentrate to obtain Coreopsis extract;

[0033] S12. Take 10 parts of Prunella vulgaris, add 12.5 times the amount of 50% ethanol to reflux and extract 3 times, each time for 1.75 hours, and filter; take the filtrate and concentrate under reduced pressure at a concentration temperature of 60°C and a vacuum of 0.08Mpa to obtain the Prunella vulgaris extract;

[0034] S13. Take 3 parts of garlic, peel them, wash them, and crush them to a particle size of 6.5mm, put them into a material cylinder, place them in an extraction kettle to start the extrac...

Embodiment 2

[0042] S21. Take 10 parts of coreopsis, crush them into coarse particles, and use 75% volume fraction of ethanol to reflux extract 3 times according to the ratio of material to liquid ratio of 1:8, each time for 3 hours, combine the extracts of 3 times, concentrate and recover under reduced pressure After the solvent, add chloroform for extraction at a ratio of 1:1, then add ethyl acetate for extraction at a ratio of 1:1, combine the two extracts, and concentrate to obtain Coreopsis extract;

[0043] S22. Take 5 parts of Prunella vulgaris, add 5 times the amount of 10% ethanol to reflux and extract twice, each time for 0.5h, and filter; take the filtrate and concentrate under reduced pressure at a concentration temperature of 55°C and a vacuum degree of 0.07Mpa to obtain the Prunella vulgaris extract;

[0044] S23. Take 1 portion of garlic, peel it, wash it, and crush it to a particle size of 6 mm, put it into a material cylinder, place it in an extraction kettle to start the e...

Embodiment 3

[0052] S31. Take 20 parts of coreopsis, crush them into coarse particles, and use 75% ethanol to reflux extract 3 times according to the ratio of solid to liquid ratio of 1:8, each time for 3 hours, combine the extracts for 3 times, concentrate and recover under reduced pressure After the solvent, add chloroform for extraction at a ratio of 1:1, then add ethyl acetate for extraction at a ratio of 1:1, combine the two extracts, and concentrate to obtain Coreopsis extract;

[0053] S32. Take 15 parts of Prunella vulgaris, add 20 times the amount of 90% ethanol to reflux and extract 4 times, each time for 3.0 hours, and filter; take the filtrate and concentrate under reduced pressure at a concentration temperature of 65°C and a vacuum degree of 0.09Mpa to obtain the Prunella vulgaris extract;

[0054] S33. Take 5 parts of garlic, peel them, wash them, crush them to a particle size of 7mm, put them into a material cylinder, place them in an extraction kettle to start the extraction...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating hypertension and a preparation method thereof. The preparation is prepared from the following raw materials in parts by weight: 10-20 parts of apocynum venetum extract, 10-20 parts of corn stigma extract, 10-20 parts of celery extract, 10-20 parts of sophora japonica, 5-15 parts of radix polygoni multiflori, 5-15 parts of kudzu vine root, 1-5 parts of garlic, 5-15 parts of thalictrum robustum extract, 5-15 parts of selfheal, 10-20 parts of golden wave, 20-30 parts of lalang grass rhizome, 20-30 parts of saururus chinensis, 20-30 parts of polygonum cuspidatum, 5-10 parts of cirsium japonicum and 5-10 parts of herba cepbalanoplosis segeti. The preparation has the effects of removing toxicity, stopping bleeding, diminishing inflammation, improving blood hypercoagulability state, dredging micro-circulation, promoting blood circulation to remove stasis, reducing blood fat, nourishing yin, purging internal fire, smoothing blood circulation, stabilizing blood pressure without rebound, reinforcing body immunity and relieving occurrence of hypertensive complications, and has the advantages of small side effect, quick response, simple preparation process and convenience in popularization.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine preparation for treating hypertension and a preparation method thereof. Background technique [0002] At present, there are many kinds of medicines that use western medicine to treat hypertension at home and abroad, such as diuretic and antihypertensive agent hydrochlorothiazide, calcium ion antagonists such as nifedipine, angiotensin converting enzyme inhibitor captopril, etc. However, because chemical drugs are artificially synthesized, there are varying degrees of toxic and side effects, such as drowsiness, dizziness, abdominal distension, and nausea. Long-term use of certain drugs can even cause angina pectoris and blood cell reduction, which aggravate the patient's condition. In contrast, traditional Chinese medicine comes from nature, has moderate and stable effects, has the function of overall regulation, has few adverse reactions, less depe...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P9/12
Inventor 李越凡尹刚彭静
Owner QINGDAO CENT HOSPITAL
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