Maximally tilted fiber bragg grating SPR (Surface Plasmon Resonance) biochemical sensor and manufacture method thereof

Abstract

The invention discloses a maximally tilted fiber bragg grating SPR (Surface Plasmon Resonance) biochemical sensor and a manufacture method of the maximally tilted fiber bragg grating SPR biochemical sensor. The maximally tilted fiber bragg grating SPR biochemical sensor comprises an optical fiber core and an optical fiber cladding layer wrapping the optical fiber core. The maximally tilted fiber bragg grating SPR biochemical sensor is characterized in that: a first tilted fiber Bragg grating is arranged at the front section of the optical fiber core and is used as a polarizer of the maximally tilted fiber bragg grating SPR biochemical sensor; an included angle of a tilted grating stripe and an optical fiber longitudinal axis of the first tilted fiber Bragg grating is 45 degrees; a second tilted fiber Bragg grating is arranged at the middle section of the optical fiber core, and an included angle of a tilted grating stripe and an optical fiber longitudinal axis of the second tilted fiber Bragg grating is 79-84 degrees; and a metal film layer or a gold nanoparticle layer is coated on the outer surface of the second tilted fiber Bragg grating as a surface plasmon wave carrier. According to the maximally tilted fiber bragg grating SPR biochemical sensor, the maximally tilted fiber bragg grating is adopted to excite surface plasmon waves to measure biomolecules or chemical components, and the maximally tilted fiber bragg grating SPR biochemical sensor can be widely applied to the fields such as biology, chemical engineering, medical science, bioscience and the like.

Description

technical field [0001] The invention relates to an optical fiber sensor, in particular to an SPR biochemical sensor with a very large dip angle optical fiber grating and a manufacturing method thereof. Background technique [0002] Surface plasmon resonance (SPR) sensor is an optical sensor based on the principle that the propagation constant of surface plasmon wave (SPW) at the interface between metal and dielectric is sensitive to the refractive index of the external environment. In 1983, Liedberg et al. first applied SPR technology to the field of gas detection and biosensing, which led to the advent of Biacore, the world's first commercial SPR sensor, in 1990. For more than 20 years since then, relevant scholars at home and abroad have conducted extensive research on the principles and applications of various SPR biochemical (referred to as "biochemical") sensors in the fields of physics, chemistry, and especially biological detection, such as: hydrogen, trinitrotoluene ...

AI Technical Summary

Problems solved by technology

Although the refractive index sensitivity of traditional multimode fiber optic SPR sensors is already high (>2000nm / RIU), their main problem is that the polarization states and energy distribution of all possible cladding modes must be precisely controlled and kept stable In order to ensure the stability of the phase matching state of SPR, this requires that the emission conditions of the optical fiber input end must be strictly controlled, and a short, non-sharply bent optical fiber should be used, and the optical fiber should not be displaced during experiments or in use.

However, the refractive index sensitivity of the general small angle (2000nm / RIU)

And up to now, about the SPR biochemical sensor based on the extremely inclined fiber Bragg grating that the present invention proposes, there is no relevant report both at home and abroad.

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