Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A pharmaceutical composition for preventing and/or treating allergic rhinitis and allergic asthma

A technology for allergic rhinitis and allergic asthma, which is applied in the field of pharmaceutical compositions for preventing and/or treating allergic rhinitis and allergic asthma, and can solve problems such as liver and kidney damage, pigmentation, infection and the like

Active Publication Date: 2017-11-03
吉林一正药业集团有限公司
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in the long-term application, it is found that the above-mentioned medicines have the following disadvantages: 1. The side effects are large, and many antihistamines and hormone drugs will cause sleepiness and fatigue. In addition, liver and kidney damages are also caused, and severe cases will also cause obesity, infection, Pigmentation etc.
2. Recurrent attacks, treating the symptoms but not the root cause
Traditional Chinese medicine treatment of allergic rhinitis mostly takes a long course of treatment, the curative effect is not exact, and it is easy to relapse

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A pharmaceutical composition for preventing and/or treating allergic rhinitis and allergic asthma
  • A pharmaceutical composition for preventing and/or treating allergic rhinitis and allergic asthma
  • A pharmaceutical composition for preventing and/or treating allergic rhinitis and allergic asthma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1, prepare the granule of Chinese medicine composition

[0044] Take 75g Radix Astragali, 60g Radix Paeoniae Alba, 50g Guizhi, 50g Ginger, 50g Bitter Almond, 30g Fangfeng, 15g Cicada Slough, 30g Tangerine, 70g Jujube (pitted) and 50g Licorice (Honey Roasted). The above medicinal materials were decocted and extracted twice, the amount of water added was 8 times and 6 times of the total mass of the medicinal materials, and the extraction time was 3 hours and 2 hours respectively. After each extraction was completed, filtered, and the combined filtrate was concentrated to a relative density of 1.10 (measured at 70°C), let cool, add 80% (volume percentage) ethanol to make the alcohol content reach 50% (volume percentage), stir well, let stand for 48 hours, and take the supernatant Recover the ethanol to the utmost, concentrate the medicinal solution to a thick paste with a relative density of 1.20 (measured at 70°C), dry, pulverize, pass through a 80-120 mesh sie...

Embodiment 2

[0045] Embodiment 2, prepare the capsule of Chinese medicine composition

[0046] Take 150g astragalus, 120g white peony root, 100g cinnamon stick, 100g ginger, 100g bitter almond, 60g windproof, 30g cicada slough, 60g orange red, 140g jujube (pitted) and 100g licorice (honey roasted). Add water 10 times the total weight of the medicinal materials to the above medicinal materials, decoct and extract for 3 hours, after the extraction is completed, filter, the filtrate is concentrated to a clear paste with a relative density of 1.15 (measured at 70°C), let it cool, and add 90% (volume percentage content) of ethanol to make the alcohol content reach 60% (volume percentage content), stir evenly, leave standstill for 24 hours, take the supernatant and reclaim the ethanol to the utmost, and the medicinal solution is concentrated to a relative density of 1.25 (measured at 70°C) The thick ointment is dried, pulverized, passed through a 80-120 mesh sieve, added 0.08 times the starch an...

Embodiment 3

[0047] Embodiment 3, prepare the capsule of Chinese medicine composition

[0048] Take 120g astragalus, 20g white peony root, 80g cassia twig, 20g ginger, 80g bitter almond, 10g windproof, 24g cicada slough, 12g orange red, 115g jujube (pitted) and 20g licorice (honey-roasted) ten-flavored medicinal materials, Add water to decoct and extract the above medicinal materials twice, the amount of water added is 8 times and 6 times the mass of the medicinal materials respectively, the extraction time is 3 hours and 2 hours respectively, after each extraction is completed, filter, and the combined filtrate is concentrated to a relative density of 1.15 (measured at 70°C), let cool, add 70% (volume percentage) ethanol to make the alcohol content reach 40% (volume percentage), stir well, leave standstill for 12 hours, get the supernatant and reclaim Ethanol is exhausted, and the medicinal solution is concentrated to a thick paste with a relative density of 1.35 (measured at 70° C.), dri...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition for preventing and / or treating allergic diseases and preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from raw materials including, by weight, 6-24 parts of astragalus, 4-20 parts of white peony root, 4-16 parts of cassia twig, 4-16 parts of fresh ginger, 4-16 parts of almond, 2-10 parts of radix sileris, 1.2-4.8 parts of cicada slough, 2.4-9.6 parts of reddish orange, 5-23 parts of jujubes (without kernels) and 4-16 parts of liquorice. The preparation method includes the steps: weighing the astragalus, the white peony root, the cassia twig, the fresh ginger, the almond, the radix sileris, the cicada slough, the reddish orange, the jujubes and the liquorice in proportion; extracting medicinal materials with water; filtering and collecting filtrate; concentrating the filtrate into extract with the relative density of 1.05-1.25 to obtain the pharmaceutical composition. The pharmaceutical composition is used for treating allergic rhinitis and allergic asthma and has the advantages of remarkable curative effect, convenience in use, rapidness in starting effects, safety, no pain and the like.

Description

technical field [0001] The invention relates to a pharmaceutical composition for preventing and / or treating allergic rhinitis and allergic asthma. Background technique [0002] Allergic diseases, also known as allergic diseases, are the most common type of chronic diseases at present. It is manifested by the human body's excessive immune response to one or more substances in the environment, resulting in damage to tissues and organs, thereby affecting normal physiological functions. Allergic diseases have a natural process of gradual deterioration, involving more tissues and organs, and may be complicated by other diseases, even life-threatening. Common allergic diseases include allergic rhinitis and allergic asthma. [0003] Allergic rhinitis (allergic rhinitis, AR) refers to the release of mediators (mainly histamine) mediated by IgE after exposure to allergens in atopic individuals, and there are a variety of immune active cells and cells Non-infectious inflammatory di...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P11/02A61P11/06A61P37/08A61K35/64
CPCA61K9/1652A61K9/2059A61K9/4866A61K35/63A61K36/238A61K36/481A61K36/484A61K36/54A61K36/71A61K36/725A61K36/736A61K36/752A61K36/9068A61K2236/333A61K2236/39A61K2300/00
Inventor 于春江
Owner 吉林一正药业集团有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products