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Traditional Chinese medicine composition with whitening and anti-aging effects and preparation method and application of extract thereof

A composition and anti-aging technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, and can solve problems such as instability of vitamin C and SOD, single effect of arbutin, and strong irritation of hydroquinone , to achieve the effect of inhibiting skin melanin production, promoting skin metabolism, and less skin irritation

Active Publication Date: 2015-03-25
GUANGZHOU HUIBIAO TESTING TECH CENT +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these whitening agents have many defects, such as hydroquinone is very irritating, vitamin C and SOD are very unstable, kojic acid also has certain irritation and discoloration problems, and arbutin has a single effect and poor effect, etc.

Method used

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  • Traditional Chinese medicine composition with whitening and anti-aging effects and preparation method and application of extract thereof
  • Traditional Chinese medicine composition with whitening and anti-aging effects and preparation method and application of extract thereof
  • Traditional Chinese medicine composition with whitening and anti-aging effects and preparation method and application of extract thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1 Preparation of Chinese medicine composition (I) and its extract

[0017] Take 100g each of Asparagus, evening primrose, papaya, pomegranate peel, knotweed, Selaginella, Cynomorium, and Oldenlandia diffusa, crush them and mix them evenly after passing through a 40-mesh sieve. Add 6.4 kg of 95% ethanol aqueous solution. Heat reflux extraction for 60 minutes, repeat extraction 3 times, combine the extracts, decolor and filter with activated carbon, and concentrate the filtrate under reduced pressure to an extract shape, which is then obtained.

Embodiment 2

[0018] Example 2 Preparation of Chinese medicine composition (II) and its extract

[0019] Take 50g of Asparagus, 80g of evening primrose, 100g of papaya, 150g of pomegranate peel, 70g of Polygonum cuspidatum, 60g of Selaginella, 90g of Cynomorium, 150g of Oldenlandia diffusa, crush it, pass a 40-mesh sieve and mix well, add 70% mass fraction 7.5 kg of ethanol aqueous solution, heated and refluxed for 90 minutes, repeated extraction twice, combined the extracts, decolorized with activated carbon, filtered, the filtrate was concentrated under reduced pressure to an extract, and it was obtained.

Embodiment 3

[0020] Example 3 Preparation of Chinese medicine composition (III) and its extract

[0021] Take 60g of Asparagus, 100g of evening primrose, 60g of papaya, 120g of pomegranate peel, 90g of Polygonum cuspidatum, 80g of Selaginella, 100g of Cynomorium, 90g of Oldenlandia diffusa, pulverize, pass through a 40-mesh sieve and mix well, add 50% mass fraction After heating and refluxing the ethanol solution for 60 minutes, the extraction was repeated 3 times. The extracts were combined, decolorized with activated carbon, filtered, and the filtrate was concentrated under reduced pressure to an extract form.

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Abstract

The invention discloses a traditional Chinese medicine composition with whitening and anti-aging effects and a preparation method and application of an extract thereof. The traditional Chinese medicine composition disclosed by the invention is prepared from the following ingredients in percentage by weight: 1-30% of radix asparagi, 1-30% of evening primrose, 3-50% of chaenomeles lagenaria, 3-50% of pomegranate peel, 1-30% of giant knotweed rhizome, 3-40% of herba selaginellae, 2-30% of cynomorium songaricum and 2-40% of oldenlandia diffusa. The extract of the traditional Chinese medicine composition disclosed by the invention plays roles in inhibiting melanocytes, inhibiting tyrosinase and resisting free radicals and ultraviolet rays, can be used for effectively inhibiting the generation of skin melanin, and has excellent whitening and anti-aging effects. The composition does not contain chemically-synthesized substances, is free from toxic or side effects, is low in skin irritation and stable in nature, and is safe and reliable.

Description

Technical field [0001] The invention relates to a compound traditional Chinese medicine composition. The extract of the traditional Chinese medicine composition has whitening and anti-aging effects, can be applied to skin whitening and anti-aging cosmetics, and belongs to the field of fine chemicals. Background technique [0002] Skin whitening and anti-aging are the themes of cosmetics, and cosmetics with skin whitening and anti-aging functions are one of the best-selling cosmetics. Modern scientific research has proved that skin aging is a very complicated process, which is affected by many factors, among which the production of melanin and the degeneration of skin elastic fibers caused by free radicals are the two main factors. The formation process of melanin is: tyrosine in human skin melanocytes is oxidized to dopa and dopaquinone under the catalysis of tyrosinase, and after rearrangement, it is further oxidized to produce dopa pigment, 5,6-di Hydroxyindole, indolequinone,...

Claims

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Application Information

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IPC IPC(8): A61K36/8965A61K8/97A61P17/18A61P17/16A61Q19/02A61Q19/08
Inventor 龚盛昭
Owner GUANGZHOU HUIBIAO TESTING TECH CENT
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