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Optimization method of light projection direction in photodynamic therapy

A technology of photodynamic therapy and optimization method, applied in the processing of 3D images, computer-aided medical procedures, image data processing, etc., can solve the problems of low light irradiance and uneven light reception in the lesion area.

Inactive Publication Date: 2017-04-19
BEIJING INSTITUTE OF TECHNOLOGYGY
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Problems solved by technology

[0004] The purpose of the present invention is to provide a method for optimizing the direction of illumination. According to the optimization method, the ideal direction of illumination can be optimized and the position information of the optimized light projection device can be obtained, which can improve the lesion area in photodynamic therapy such as port wine stains In the case of uneven light reception and low light irradiance

Method used

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  • Optimization method of light projection direction in photodynamic therapy
  • Optimization method of light projection direction in photodynamic therapy
  • Optimization method of light projection direction in photodynamic therapy

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Embodiment Construction

[0024] The specific implementation of the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0025] figure 2 In order to establish a binocular stereo vision system with cameras and projectors, the three-dimensional point cloud information of the lesion area is obtained based on the three-dimensional measurement principle of the stereo vision system. During the light projection control process, a three-dimensional space is established with the camera coordinate system, and the projector is used as a light projection device to illuminate the lesion area.

[0026] 1) Smooth and resample the point cloud based on polynomial fitting, triangulate the point cloud with the Delaunay algorithm, and calculate the area and center of gravity of the triangle patch.

[0027] 2) The projector is used as a light projection device. According to the parameters of the vision system, the initial position information of the ...

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Abstract

The invention relates to an optimization method of a projection direction used for controlling a projection device for nevus flammeus and the like in a PDT (Photodynamics Therapy). The method comprises the steps of optimizing a lighting direction in accordance with a normal vector weighting corresponding to 3D (three-dimension) surface patch of a focus under the precondition of obtaining a 3D focus area, and reducing a lighting angle formed between incident light and the D surface of the focus. In addition, the projection device can be controlled to light in an optimized direction by using the parameters of a visual system to obtain a position coordinate of the projection device, thereby improving the single lighting efficiency of the projection device and improving the curative effect of the single PDT.

Description

technical field [0001] The invention relates to a method for optimizing the direction of photodynamic light projection, especially for the control of light projection devices in photodynamic therapy such as port wine stains. On the premise of obtaining the three-dimensional lesion area, the method is based on the corresponding three-dimensional curved surface block of the lesion. Normal vector weighting optimizes the direction of illumination, reduces the angle of illumination formed between the incident light and the three-dimensional surface block of the lesion, improves the efficiency of single illumination of the light projection device, and then improves the efficacy of single photodynamic therapy for port wine stains. Background technique [0002] Port Wine Stains (PWS), commonly known as "red birthmark", is a congenital skin disease caused by malformation and abnormal expansion of capillary vessels in the superficial dermis. Accounting for three to five per thousand, t...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T15/50G06T17/00
CPCG06T17/00
Inventor 胡晓明张凤娟曹群李勤
Owner BEIJING INSTITUTE OF TECHNOLOGYGY
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