Pharmaceutical composition for treating obesity
A composition and obesity technology, applied in the field of pharmaceutical compositions for the treatment of obesity, can solve the problems of not considering obesity-associated diseases and the like
Inactive Publication Date: 2015-01-14
WUXI XINDA MEDICAL DEVICE
View PDF0 Cites 4 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
[0013] In the prior art, most of the treatment of obesity only considers the obesity itself, but do...
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreExamples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0023] A pharmaceutical composition for treating obesity, characterized in that it comprises a therapeutically effective amount of 1-isopropyl-1'-(1-methyl-2-oxo-2,3-dihydro-1H-benzene And[d]imidazole-5-carbonyl)-4,6-dihydrospiro[indazole-5,4'-piperidin]-7(1H)-one, and a therapeutically effective amount of 4-[5-cyano -4-({2-fluoro-4-[(2-hydroxyethyl)sulfonyl]phenoxy}methyl)-1H-pyrazol-1-yl]piperidine-1-carboxylic acid isopropyl ester; two The mass ratio of the latter is 1:1.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more PUM
Login to view more
Abstract
The invention discloses a pharmaceutical composition for treating obesity-related diseases. The composition contains a therapeutically-effective amount of 1-isopropyl-1'-(1-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-carbonyl)-4,6-dihydrospiro[indazol-5,4'-piperidine]-7(1H)-one and a therapeutically-effective amount of 4-[5-cyano-4-({2-fluoro-4-[(2-hydroxyethyl) sulfonyl]phenoxy}methyl)-1H-pyrazol-1-yl]piperidin-1-isopropyl formate which have the mass ratio of (3: 1) to (1: 3). By using the two kinds of drugs in a combined manner, symptoms, such as hypertension and diabetes, caused by obesity can be treated while the obesity is treated.
Description
technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating obesity. Background technique [0002] Obesity is a state of excessive accumulation of body fat, especially triglycerides (triacylglycerols). Usually due to excessive food intake or changes in body metabolism, excessive fat accumulation in the body results in excessive weight gain and pathophysiological changes in the human body. Body mass index (BMI) is the square of weight (Kg) divided by height (m), and is an indicator for assessing the degree of obesity. In Europe and America, BMI≥25kg / m 2 Overweight, BMI≥30kg / m 2 for obesity. People in the Asia-Pacific region can be divided according to their BMI: healthy 18.5-22.9kg / m 2 ;Overweight 23-24.9kg / m 2 ; Level 1 obesity 25-29.9kg / m 2 ;2 degree obesity 30-34.9kg / m 2 ; Grade 3 obesity > 35kg / m 2 . [0003] Obesity can cause high blood pressure (the incidence of obesity is 25-55%),...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more Application Information
Patent Timeline
Login to view more
IPC IPC(8): A61K31/454A61K31/438A61P3/04A61P9/12A61P3/10
CPCA61K31/454A61K31/438
Inventor 王岳荣
Owner WUXI XINDA MEDICAL DEVICE
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Try Eureka
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap