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Traditional Chinese medicine composition for treating myocardial infarction and application of traditional Chinese medicine composition

A technique for myocardial infarction and composition, applied in the field of medicine, can solve the problems of lack of means for pathological treatment, lack of major development, and inability to recover, and achieves the effects of good application prospects, good treatment of myocardial infarction and myocardial infarction, and easy availability of raw materials

Inactive Publication Date: 2014-12-10
张玉清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the drugs for the treatment of myocardial infarction are mainly based on western medicine, but western medicine can only relieve symptoms, lack of means for pathological treatment, and are prone to recurrence
In recent years, although both home and abroad have tried to use traditional Chinese medicine to treat myocardial infarction, they have not made great progress. Some traditional Chinese medicines have a certain effect on the treatment of myocardial infarction, but they cannot be cured, and the recurrence rate is high.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1 Chinese medicine composition mixture of the present invention

[0015] Prescription: Sanqi 150g, Akebia 60g, Eucommia 100g, Acanthopanax 100g, Chuanxiong 100g, Puhuang 200g, Lotus Heart 200g, Poria 100g, Paeoniae Alba 50g, Ginkgo biloba 50g, Licorice 100g, Coptidis 80g, Pueraria 120g, Achyranthes bidentata 120g.

[0016] Preparation method: Weigh each medicinal material in parts by weight of the prescription, add water 7 times the total weight of medicinal materials, soak at room temperature for 10 minutes, decoct 4 times at 60°C for 60 minutes each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to relative density For the extract of 1.05, the relative density is the test result at 60°C. Add ethanol to the extract until the alcohol content is 60%. After standing at room temperature for 24 hours, take the supernatant, recover the ethanol until it is concentrated, and add water to 1000ml , stir well, sub-package, an...

Embodiment 2

[0017] Embodiment 2 Chinese medicine composition tablet of the present invention

[0018] Prescription: Sanqi 1500g, Akebia 600g, Eucommia 1000g, Acanthopanax 1000g, Chuanxiong 1000g, Puhuang 2000g, Lotus Heart 2000g, Poria 1000g, Paeoniae Alba 500g, Ginkgo biloba 500g, Licorice 1000g, Coptis 800g, Pueraria 1200g, Achyranthes bidentata 1200g.

[0019] Preparation method: Weigh the medicinal materials in the prescription weight, add water 10 times the total weight of the medicinal materials, soak at room temperature for 60 minutes, decoct at 90°C for 2 times, 60 minutes each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to relative density 1.25 extract, the relative density is the test result at 60°C, add ethanol to the extract until the alcohol content is 90%, take the supernatant after standing at room temperature for 24 hours, recover the ethanol until concentrated, and vacuum dry , Granulating, tableting.

Embodiment 3

[0020] Embodiment 3 Chinese medicine composition capsule of the present invention

[0021] Prescription: Sanqi 15kg, Akebia 6kg, Eucommia 10kg, Acanthopanax 10kg, Chuanxiong 10kg, Puhuang 20kg, Lotus Heart 20kg, Poria 10kg, Paeoniae Alba 5kg, Ginkgo Leaf 5kg, Licorice 10kg, Coptidis 8kg, Pueraria 12kg, Achyranthes bidentata 12kg.

[0022] Preparation method: Weigh each medicinal material in the weight part of the prescription, add water 8 times the total weight of the medicinal material, soak at room temperature for 30 minutes, decoct 3 times at 60-90°C for 90 minutes each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to The extract with a relative density of 1.15, the relative density is the test result at 60°C, add ethanol to the extract until the alcohol content is 75%, leave it at room temperature for 24 hours, take the supernatant, recover the ethanol until concentrated, vacuum Dry, granulate, and pack into capsules.

[0023] Th...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating myocardial infarction and application of the traditional Chinese medicine composition in preparing a medicament for preventing or treating myocardial infarction. Aiming at the problem that the conventional chemical medicament for treating myocardial infarction is higher in liver toxicity, the invention provides the traditional Chinese medicine composition for treating myocardial infarction. The traditional Chinese medicine composition consists of the following components in parts by weight: 15 parts of pseudo-ginseng, 6 parts of akebiaquinata, 10 parts of eucommia, 10 parts of acanthopanax, 10 parts of ligusticum wallichii, 20 parts of typhae pollen, 20 parts of lotus nuts, 10 parts of poria cocos, 5 parts of white peony roots, 5 parts of folium ginkgo, 10 parts of liquorice, 8 parts of coptidis rhizome, 12 parts of puerarin and 12 parts of achyranthes bidentata. The traditional Chinese medicine composition has an extremely good treating effect on myocardial infarction and has an outstanding clinical popularization value.

Description

technical field [0001] The invention belongs to the field of medicine and relates to a traditional Chinese medicine composition and its application, in particular to a traditional Chinese medicine composition for treating myocardial infarction and its application as a medicine for myocardial infarction. Background technique [0002] Myocardial infarction is myocardial necrosis caused by acute and persistent coronary ischemia and hypoxia. Clinically, there are often severe and persistent substernal pains, which cannot be completely relieved by rest and nitrates, accompanied by increased serum myocardial enzyme activity and progressive ECG changes, which may be complicated by arrhythmia, shock or heart failure, often life-threatening. The disease is most common in Europe and the United States, and about 1.5 million people in the United States suffer from myocardial infarction every year. China has shown a clear upward trend in recent years, with at least 500,000 new cases and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P9/10
Inventor 陈远征
Owner 张玉清
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