Human parainfluenza virus (HPIVs) IgM antibody detection test strip and preparation method thereof

Abstract

The invention provides a human parainfluenza virus (HPIVs) IgM antibody detection test strip and a preparation method thereof. The human parainfluenza virus (HPIVs) IgM antibody detection test strip comprises a PVC bottom plate, a sample pad, a water absorption pad, a gold pad coated with an HPIVs specificity recombinant antigen, a detection line coated with a mouse anti-human IgM polyclonal antibody, and a nitrocellulose membrane (NC membrane) coated with a quality control line of a polyclonal antibody of an anti-HPIVs recombinant antigen. The human parainfluenza virus specific antibody IgM in serum of a human body is rapidly detected by applying an immunochromatographic method so that the acute infection of human parainfluenza viruses is conveniently subjected to differential diagnosis, and the certain significance is achieved for the clinical laboratory medicine.

Description

technical field [0001] The invention relates to the technical field of medical testing, in particular to a human parainfluenza virus IgM antibody detection test strip and a preparation method thereof. Background technique [0002] Human parainfluenza viruses (HPIVs) are viruses that cause lower respiratory tract infections in children. Serologically, HPIVs can be divided into 4 types (type I to type IV), which can cause recurrent upper respiratory tract infections (such as colds and sore throats). ), which can also cause severe recurrent lower respiratory tract disease (such as pneumonia, bronchitis, and bronchiolitis), especially in the elderly and in immunocompromised persons. [0003] At present, the methods for clinically diagnosing HPIVs infection include: first through tissue culture, then isolate and identify the virus in the cells or directly detect the virus present in respiratory secretions, including the use of immunofluorescence test, PCR, enzyme-linked immunorea...

AI Technical Summary

Problems solved by technology

At present, a relatively advanced detection method is to detect by immunofluorescence, but this detection method can only detect a corresponding substance at a time, the sensitivity is poor, and the effect is sometimes unsatisfactory