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A kind of cistanche wall-breaking preparation

A technology of Cistanche deserticola and preparation, which is applied in the field of traditional Chinese medicine, can solve the problems of incomplete decoction of ingredients, loss of effective ingredients, easy moisture absorption, etc., and achieves the effects of overcoming the decrease in dissolution rate, being convenient for brewing with warm water, and being easy to disintegrate and disperse.

Active Publication Date: 2016-09-07
ZHONGSHAN ZHONGZHI PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Using the traditional decoction method, on the one hand, it is easy to destroy the heat-sensitive ingredients, and on the other hand, the incomplete decoction of the ingredients will cause the loss of active ingredients.
The preparation of cistanche into superfine powder of cistanche is beneficial to improve the utilization rate of active ingredients, but at the same time, due to the increase of the specific surface area of ​​the powder, it has the disadvantages of easy moisture absorption, oxidation, deterioration, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Take the pure medicinal material of Cistanche deserticola, coarsely pulverize it into a coarse powder of about 100 meshes, and superfinely pulverize it into a powder in which 90% of the particles in the ultrafine powder have a particle size less than or equal to 38 μm, add ethanol-water solution (the mass fraction of ethanol is 50% ) soft material by wet method, the ratio of solution to superfine powder is 0.45︰1 (by weight), after mixing, pre-installed 10-mesh sieve, the extrusion speed is 50r / min, and the extrusion force is 1MPa to make wet granules , the wet granules were placed in a hot air circulation oven, the drying temperature was set at 70°C, and dried for 2.0 hours until dry.

[0025]

[0026] Note: The full score is 10.

Embodiment 2

[0028] Take the pure medicinal material of Cistanche deserticola, coarsely pulverize it into a coarse powder of about 100 meshes, and then superfinely pulverize it into a powder in which 90% of the particles in the ultrafine powder have a particle size less than or equal to 38 μm, add ethanol-water solution (the mass fraction of ethanol is 60% ) soft material by wet method, the ratio of solution to superfine powder is 0.5︰1 (by weight), after mixing, pre-installed 10-mesh sieve, the extrusion speed is 55r / min, and the extrusion force is 0.9MPa to make wet Granules, wet granules are transferred to a vacuum microwave drying oven, set the drying temperature to 45°C, and dried for 0.75h until dry.

[0029]

[0030] Note: The full score is 10.

Embodiment 3

[0032] Take the pure medicinal material of Cistanche deserticola, coarsely pulverize it into a coarse powder of about 100 meshes, and then superfinely pulverize it into a powder in which 90% of the particles in the ultrafine powder have a particle size less than or equal to 38 μm, add ethanol-water solution (the mass fraction of ethanol is 98%) ) soft material by wet method, the ratio of solution to superfine powder is 1.0︰1 (by weight), after mixing, pre-installed 30-mesh sieve, the extrusion speed is 100r / min, and the extrusion force is 0.05MPa to make wet Granules, wet granules are transferred to a hot air circulation oven, set the drying temperature to 70°C, and dried for 2.0 hours to dryness.

[0033]

[0034] Note: The full score is 10.

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Abstract

The invention relates to a traditional Chinese medicine preparation, in particular to a Cistanche wall-breaking preparation. The invention grinds Cistanche deserticola into ultra-fine powder, further granulates through ethanol-water wet method, extrudes at a certain speed, and dries. Moreover, the preparation has strong stability and good disintegration.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a Cistanche wall-breaking preparation. Background technique [0002] Ultrafine pulverization technology is a new technology developed rapidly in recent years. Most of the active ingredients in Chinese herbal medicines are distributed in the cells. Conventional decoction pieces can only release part of the active ingredients, and the utilization rate of active ingredients is 10-30%. However, using the wall-breaking crushing technology, such as crushing Chinese herbal medicine pieces to 300 mesh About 86.7% of the cell wall breaking rate will increase the dissolution of the active ingredients in the medicinal materials, greatly enhance its efficacy, and the utilization rate of the active ingredients will be above 90%, so as to reduce the amount of medicinal materials used and protect the medicinal materials resources. The quality increases the efficacy. However, the cu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/64
Inventor 成金乐陈勇军钱锦花梁燕玲王慧玲
Owner ZHONGSHAN ZHONGZHI PHARMA GRP
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