Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of swertisin and derivative thereof

A technology of use and medicine, which is applied in the field of flavin and its derivatives as a drug, can solve the problem of antidepressant effect of flavin that has not been seen yet

Active Publication Date: 2014-09-03
SICHUAN ACAD OF CHINESE MEDICINE SCI
View PDF2 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no report that the drug flavin has antidepressant effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of swertisin and derivative thereof
  • Application of swertisin and derivative thereof
  • Application of swertisin and derivative thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The preparation of embodiment 1 tablet of the present invention

[0039] Raw materials: flavin 500mg, starch 500g, lactose 300g, magnesium stearate 50g.

[0040] Preparation method: mix the flavin, starch and lactose, granulate it by conventional method, add magnesium stearate to granulate, press into tablets, make 10,000 tablets in total, and obtain a preparation containing 50 μg of flavin in each tablet.

Embodiment 2

[0041] The preparation of embodiment 2 capsules of the present invention

[0042] Raw materials: flavin 500mg, starch 2000g.

[0043] Preparation method: after uniformly mixing the flavin and starch, pack it into capsules, make 10,000 capsules in total, and obtain a preparation containing 50 μg of the flavin extract in each capsule.

Embodiment 3

[0044] The preparation of embodiment 3 tablet of the present invention

[0045] Raw materials: flavin 1000mg, starch 500g, lactose 300g, magnesium stearate 50g.

[0046] Preparation method: mix the flavin, starch and lactose, granulate it by conventional method, add magnesium stearate to granulate, press into tablets, make 10,000 tablets in total, and obtain a preparation containing 100 μg of flavin in each tablet.

[0047]Prove beneficial effect of the present invention by pharmacodynamic test below.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a novel application of swertisin and a derivative thereof in preparing an antidepressant drug. The swertisin has an obvious antidepressant effect, can significantly improve functions of a monoamine neurotransmitter system, has an auxiliary therapeutic effect for depression and symptoms thereof, and provides a novel selection for treating depression clinically.

Description

technical field [0001] The present invention relates to the new application of flavin and its derivatives. Background technique [0002] Depression, belonging to mood disorders, is a syndrome characterized by significant and persistent low mood, accompanied by slow thinking, weakened will activity, and various physical symptoms. Depression is a common and frequently-occurring disease that endangers human physical and mental health, and is a major global mental problem. Its lifetime prevalence rate is 6.1%-9.5%, and about 13%-20% of people have experienced depression in their lives. Fifteen percent of people with major depressive disorder die by suicide, and suicide deaths are estimated to be as high as 1 million a year. The World Health Organization (WHO) estimates that there are about 350 million patients with depression in the world. In 1996, a survey on the "burden of disease" published by WHO showed that: based on the statistics of disability (functional impairment) cau...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/7048A61K31/352A61P25/24
Inventor 江南罗霞许晓燕魏巍余梦瑶
Owner SICHUAN ACAD OF CHINESE MEDICINE SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com