Atomized liquid for inhalation injury of respiratory tract

A technology of inhalation injury and atomized liquid, which is applied in the direction of respiratory diseases, aerosol delivery, medical preparations containing active ingredients, etc. It can solve problems such as tracheal or bronchospasm, long hospital stay, and shedding necrotic tissue. Achieve the effects of reducing airway hyperresponsiveness, relieving pleural irritation symptoms, and increasing lung ventilation

Inactive Publication Date: 2014-08-20
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional airway care methods (including airway humidification, sputum suction, etc.) cannot completely and effectively remove respiratory secretions, inhaled smoke particles and exfoliated necrotic tissue
In clinical nursing, tracheotomy is required for most patients with moderate or higher levels, so that dyspnea can be improved.
However, this kind of artificial airway has the following disadvantages: ①It is invasive care, and the patient suffers a lot; ②The risk of nosocomial infection is high; ③Long hospitalization time
[0004] The reason why the existing moderate respiratory burns are not effective through conventional airway care methods is that simple airway humidification and sputum suction only dilute and discharge the increased respiratory secretions and inhaled smoke particles, while burning causes respiratory damage. Its pathological basis lies in varying degrees of protein denaturation of the mucosa, resulting in the appearance of a large number of protein particles and exfoliated necrotic tissue, leading to respiratory mucosal hyperemia, tracheal or bronchospasm, edema, asphyxia, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1, the weight ratio of raw materials: persimmon calyx 20g, decalyx eggplant 10g, mountain cucumber 6g, bergamot 10g, Sanhexiang 6g, aurantium aurantium 10g, August Zha 10g, Chuan Duan 10g, Smilax 10g, black Medicine 2g, yam medicine 6g, deer horn glue 20g.

[0030] The preparation method of Example 1 is: mix persimmon calyx, ten calyx eggplant, mountain cucumber, bergamot, syringa, citrus aurantium, August, chuanduan, smilax, black medicine, yam, and antler glue, add water and decoct Boil, take the filtrate after 30 minutes, add water to the dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, concentrate to 80ml, divide into two parts, and use it for morning and evening atomization inhalation.

Embodiment 2

[0031] Example 2, the weight ratio of raw materials: 10 parts of persimmon calyx, 6 parts of Shicalyx eggplant, 3 parts of mountain cucumber, 6 parts of bergamot flower, 3 parts of Sanhexiang, 6 parts of Citrus aurantium, 6 parts of August Zha, Chuan Duan 6 parts, 6 parts of Smilax smilax, 1 part of black medicine, 3 parts of Chinese yam, 10 parts of deer horn glue.

Embodiment 3

[0032] Example 3, the weight ratio of raw materials: 20 parts of persimmon calyx, 10 parts of eggplant ten calyx, 6 parts of mountain cucumber, 10 parts of bergamot, 6 parts of syringa, 10 parts of citrus aurantium, 10 parts of August Zha, Chuan Duan 10 parts, 10 parts of Smilax smilax, 2 parts of black medicine, 6 parts of Chinese yam, 20 parts of deer horn glue.

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PUM

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Abstract

The invention discloses atomized liquid for inhalation injury of respiratory tract, for solving the problem on treatment of inhalation injury of respiratory tract. The atomized liquid is characterized by being prepared from the following medicinal raw materials in parts by weight: kaki calyx, lycianthes biflora, tricyrtis root, fleshfingered citron flower, kinostemon alborubrum, immature bitter orange, fiveleaf akebia fruit, dipsacus root, rhizoma smilacis glabrae, lindera aggregate, common yam rhizome and colla cornus cervi. The clinical test shows that the atomized liquid for inhalation injury of respiratory tract has the characteristics of good treatment effect and high safety and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an atomized liquid for respiratory tract inhalation injury. Background technique [0002] Inhalation injury is relatively common in burn patients, and its condition is complex and changeable, with serious complications, high mortality rate and difficult nursing care. Patients generally have progressive dyspnea and labored breathing immediately after the injury; ECG monitors and blood gas analysis all indicate that there are varying degrees of hypoxia. This type of inhalation injury caused by burning is divided into: ① Mild respiratory injury: burns or smoke-induced damage to the mouth, nose, and nasopharynx, manifested as head and face burns or smoke-induced damage, more cough and sputum, painful swallowing, Difficult; ②moderate respiratory damage: throat and tracheal burns or damage caused by smoke, in addition to the above symptoms, irritating cough, hoarseness, fla...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61K9/12A61P11/00A61K35/32
Inventor 鲁瑞珍张志学赵景岚
Owner QINGDAO CENT HOSPITAL
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