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Pharmaceutical composition and applications thereof

A technology of composition and medicine, applied in the field of medicine

Inactive Publication Date: 2014-08-06
北京康爱医疗科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the synergistic effect of ginseng extract formulations with certain quality control and anti-tumor drugs has not been reported

Method used

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  • Pharmaceutical composition and applications thereof
  • Pharmaceutical composition and applications thereof
  • Pharmaceutical composition and applications thereof

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Experimental program
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Embodiment Construction

[0013] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0014] The invention provides an anti-tumor pharmaceutical composition, which comprises ginseng extract and anti-tumor drug component 5-FU, and the mass ratio of the ginseng extract and 5-fluorouracil is 30%-200%. Preferably, in this embodiment, the mass ratio of the ginseng extract and the antineoplastic drug component 5-FU is 1:1.

[0015] The ginseng extract includes ginsenoside Rb1, ginsenoside Re, ginsenoside Rd, ginsenoside Rb3, ginsenoside Rg3, ginsenoside Rh2, and ginsenoside Rg1. Wherein, the mass percentage of ginsenoside Rb1 is 20%-40%, the mass percentage of ginsenoside Re is 30%-50%, the mass percentage of ginsenoside Rd is 10%-30%, and the mass percentage of ginsenoside Rb3 is 5% ~20%, the mass percentage of ginsenoside Rg3 is 1%-10%, the mass percentage of ginsenoside Rh2 is 3%-20%, and the mass percentage of ginsenoside Rg1 is 8%-25%. ...

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Abstract

The invention provides a pharmaceutical composition. The pharmaceutical composition comprises ginseng extract, and an anti-tumor pharmaceutical component 5-fluorouracil, wherein preferably the mass ratio of the ginseng extract to the 5-fluorouracil is 1:1, and the ginseng extract comprises ginsenoside Rb1, ginsenoside Re, ginsenoside Rd, ginsenoside Rb3, ginsenoside Rg3, ginsenoside Rh2, ginsenoside Rg1. The pharmaceutical composition is used to enhance the curative effect of antitumor components and reduce the treatment side-effect caused by the antitumor components. The pharmaceutical composition is especially designed for treating stomach cancer diseases.

Description

【Technical field】 [0001] The invention relates to the technical field of medicine, in particular to a composition of antineoplastic drugs and its medical application. 【Background technique】 [0002] According to WHO (World Health Organization) statistics, cancer has become the number one major disease in terms of mortality among various diseases that cripple human life. In 2008 alone, there were approximately 12.7 million new cancer cases and 7.6 million cancer deaths worldwide, with approximately 70% of these deaths occurring in low- and middle-income countries. According to the statistics of international authoritative investigation agencies, the number of cancer deaths will double to more than 10 million by 2020. Currently, cancer treatments mainly include surgery, radiotherapy, and chemotherapy. Among them, chemotherapy can significantly prolong the patient's life, is suitable for almost all tumor treatments, and plays an increasingly important role in the comprehensiv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K31/704A61P35/00A61K31/513
Inventor 应希堂韩梅乔晋萍陆卫东商维虎
Owner 北京康爱医疗科技股份有限公司
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