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Medicinal composition used for treating hypertension and hyperlipidemia

A composition and a technology for hyperlipidemia, applied in the field of medicine, can solve problems such as no hypolipidemic effect, and achieve the effects of less adverse reactions, normal activity, and improvement of blood lipids

Inactive Publication Date: 2015-07-01
扬州国纬生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, it is mainly used for the treatment of diseases such as hypertension, ischemic heart disease and chronic congestive heart failure, but has no effect of lowering blood lipids

Method used

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  • Medicinal composition used for treating hypertension and hyperlipidemia
  • Medicinal composition used for treating hypertension and hyperlipidemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] According to methods known in the art to prepare composition tablets, each tablet contains the following ingredients:

[0062] compound composition tablet

[0063] Enalapril maleate 10mg, eucommia extract 40mg, psyllium seed extract 20mg, and the rest of the pharmaceutical excipients are commonly used excipients for tablet preparation.

[0064] Note: The weight of enalapril maleate is calculated by enalapril.

[0065] Preparation process: Prepared according to the conventional preparation process of photographic agent.

Embodiment 2

[0067] According to methods known in the art to prepare composition tablets, each tablet contains the following ingredients:

[0068] compound composition tablet

[0069] Enalapril maleate 5 mg, eucommia extract 20 mg, psyllium seed extract 10 mg, and the rest of the pharmaceutical excipients are commonly used excipients for tablet preparation.

[0070] Note: The weight of enalapril maleate is calculated by enalapril.

[0071] Preparation process: Prepared according to the conventional preparation process of photographic agent.

Embodiment 3

[0073] According to methods known in the art to prepare composition tablets, each tablet contains the following ingredients:

[0074] compound composition tablet

[0075] Enalapril maleate 5 mg, eucommia extract 10 mg, psyllium seed extract 20 mg, and the rest of the pharmaceutical excipients are commonly used excipients for tablet preparation.

[0076] Note: The weight of enalapril maleate is calculated by enalapril.

[0077] Preparation process: Prepared according to the conventional preparation process of photographic agent.

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PUM

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Abstract

The invention relates to a medicinal composition used for treating hypertension and hyperlipidemia. The medicinal composition used for treating the hypertension and hyperlipidemia is composed of enalapril or pharmaceutical salt thereof, bark of eucommia and plantain seed extract in a weight ratio of 1:(0.1-100):(0.1-100) and can be prepared into tablets, capsules, granules and the like. Pharmacological study on the medicinal composition used for treating the hypertension and hyperlipidemia shows that the medicinal composition has an ideal effect when being used for treating primary hypertension and hyperlipidemia, can obviously lower blood pressure of a rat and can obviously improve blood lipid level, and an unexpected technical effect is obtained.

Description

technical field [0001] The invention relates to a composition composed of enalapril or its pharmaceutically acceptable salt, Eucommia ulmoides and plantago seed extracts, and the application of this composition in the preparation of medicines for treating hypertension combined with hyperlipidemia, which belongs to the field of medical technology . Background technique [0002] my country is a big country with high blood pressure. According to statistics, one out of every five adults is a hypertensive patient. With the change of people's lifestyle in our country, this trend is still increasing. [0003] A large European evidence-based medical study (ASCOT study) showed that for hypertensive patients, even if the cholesterol level is not high, they can also benefit from lipid-lowering treatment. Hypertensive patients taking lipid-lowering drugs every day on the basis of lowering blood pressure can further reduce the risk of coronary heart disease by 36% and the risk of stroke...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/68A61P9/12A61P3/06A61K31/40
Inventor 刘俊德
Owner 扬州国纬生物科技有限公司
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