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Extraction method and application of ginseng-containing plant composition

An extraction method and composition technology, applied in the field of extraction of plant compositions containing ginseng, can solve the problems of large dosage for patients, affect clinical application, and many impurities, and achieve the effect of reducing dosage

Inactive Publication Date: 2014-05-28
XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing ginseng, but the method of powdering is rough, backward, and has many impurities, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the This product is used clinically

Method used

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  • Extraction method and application of ginseng-containing plant composition
  • Extraction method and application of ginseng-containing plant composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 75g ginseng, 150g raw rehmannia glutinosa, 150g rehmannia glutinosa, 150g wine-roasted dogwood, 300g Chinese yam, 150g Alisma, 150g cortex moutan, 150g poria cocos, 150g radix radix, 150g asparagus, crush them, add 2L of 70% ethanol, and put into microwave Microwave extraction is carried out in the extraction device, the extraction power is 400-600W, the extraction is 2 times, 4-8 minutes each time, the extracts are combined, concentrated, added to the D101 macroporous adsorption resin column, eluted with 50% ethanol, and collected 5 times Measure the column volume of the eluate, recover ethanol under reduced pressure, concentrate and dry to obtain the microwave extract, which is prepared into pills with conventional excipients, 4.5 g per tablet.

Embodiment 2

[0016] Take 75g ginseng, 150g raw rehmannia glutinosa, 150g rehmannia glutinosa, 150g wine-roasted dogwood, 300g Chinese yam, 150g Alisma, 150g cortex moutan, 150g poria cocos, 150g radix radix, 150g asparagus, crush them, add 2L of 70% ethanol, and put into microwave Microwave extraction is carried out in the extraction device, the extraction power is 400-600W, the extraction is 2 times, 4-8 minutes each time, the extracts are combined, concentrated, added to the D101 macroporous adsorption resin column, eluted with 50% ethanol, and collected 5 times Measure column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extract, add conventional auxiliary materials to prepare into pills.

Embodiment 3

[0018] Take 75g ginseng, 150g raw rehmannia glutinosa, 150g rehmannia glutinosa, 150g wine-roasted dogwood, 300g Chinese yam, 150g Alisma, 150g cortex moutan, 150g poria cocos, 150g radix radix, 150g asparagus, crush them, add 2L of 70% ethanol, and put into microwave Microwave extraction is carried out in the extraction device, the extraction power is 400-600W, the extraction is 2 times, 4-8 minutes each time, the extracts are combined, concentrated, added to the D101 macroporous adsorption resin column, eluted with 50% ethanol, and collected 5 times Measure column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extract, add conventional auxiliary materials to prepare into pills.

[0019] The Chinese medicinal materials of the present invention are pharmacopoeia varieties.

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Abstract

The invention provides an extraction method of ginseng-containing plant composition. The ginseng-containing plant composition is prepared with a microwave extraction method by the following active pharmaceutical ingredients: 75 g of ginseng, 150 g of dried rehmannia roots, 150 g of prepared rehmannia roots, 150 g of dogwood stir-fried with wine, 300 g of Chinese yam, 150 g of oriental waterplantain rhizome, 150 g of tree peony bark, 150 g of poria, 150 g of radix ophiopogonis and 150 g of cochinchinese asparagus roots, so that the content is increased greatly, and the dosage is reduced. The invention further provides application of the ginseng-containing plant composition in preparation of a cell proliferation drug for inhibiting adrenal gland pheochromocytoma PC-12 of a rat.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing ginseng. Background technique [0002] The plant composition containing ginseng is made from 75g of ginseng, 150g of rehmannia glutinosa, 150g of rehmannia glutinosa, 150g of wine-roasted dogwood, 300g of Chinese yam, 150g of Alisma, 150g of Moutan cortex, 150g of Poria, 150g of Radix Ophiopogon, and 150g of Asparagus as raw materials. Recorded in the Ministry of Health standard (WS3-B-0010-89), the current extraction method is to crush the above ten flavors into fine powder, sieve, and mix well. Add 80-100g of refined honey to every 100g of powder to make big honeyed pills. It is used for deficiency of yin and weak Qi, cough due to fatigue, palpitation, shortness of breath, hot flashes due to bone steaming, backache and tinnitus, nocturnal emission, night sweats, and dry sto...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P35/00
Inventor 李正梅
Owner XINXIANG MEDICAL UNIV
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