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Extract of traditional Chinese medicine composite with anti-allergy effect, and application of extract

A composition and extract technology, which is applied to the extract of traditional Chinese medicine composition with anti-allergic effect and its application field, can solve the problems of irritation, safety risk, general anti-allergic effect, etc. anti-allergic effect

Active Publication Date: 2014-04-30
GUANGDONG IND TECHN COLLEGE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These antisensitizers all have certain defects, such as dipotassium glycyrrhizinate will increase the ion content in the cosmetics, making the cosmetics unstable; ɑ-bisabolol itself has irritation, and the antisensitivity effect is general; It has photosensitivity reaction, there are safety risks, and the effect of single traditional Chinese medicine is not good

Method used

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  • Extract of traditional Chinese medicine composite with anti-allergy effect, and application of extract
  • Extract of traditional Chinese medicine composite with anti-allergy effect, and application of extract
  • Extract of traditional Chinese medicine composite with anti-allergy effect, and application of extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 Preparation of traditional Chinese medicine composition (I) and its extract

[0015] Take 25g of white fresh skin, 15g of comfrey, 20g of Fangfeng, 15g of angelica, 15g of Polygonatum odoratum, 10g of licorice, grind them, mix them evenly, add 1L of ethanol with a mass fraction of 70%, heat and reflux for extraction twice, each time for 1.5h, and combine The extract was concentrated under reduced pressure at 60°C until there was no alcohol smell, and then purified on an AB-8 macroporous resin column, and the eluted part with a mass fraction of 70% ethanol was collected, concentrated under reduced pressure to obtain 60mL concentrated solution, and then added 40mL Butanediol was filtered to obtain the extract of 100mL of Chinese medicine composition, its solid content was 9.6%, and the pH value was 5.84.

[0016]

Embodiment 2

[0017] Example 2 Preparation of traditional Chinese medicine composition (Ⅱ) and its extract

[0018] Take 20g of white fresh skin, 12g of comfrey, 18g of Fangfeng, 14g of angelica, 20g of Polygonatum odoratum, 16g of licorice, grind them, mix them evenly, add 1.2L of ethanol with a mass fraction of 60%, heat and reflux for three times, each time for 1h, and combine the extractions solution, concentrated under reduced pressure at 60°C until there is no alcohol smell, then purified on an AB-8 macroporous resin column, collected ethanol eluting fractions with a mass fraction of 70%, concentrated under reduced pressure to obtain 50mL concentrated solution, and then added 50mL Butanediol was filtered to obtain the extract of 100mL Chinese medicine composition, its solid content was 10.5%, and the pH value was 5.92.

[0019]

Embodiment 3

[0020] Example 3 Preparation of traditional Chinese medicine composition (Ⅲ) and its extract

[0021] Take 22g of white fresh skin, 15g of comfrey, 17g of Fangfeng, 13g of angelica, 16g of Polygonatum odoratum, 17g of licorice, grind them, mix them evenly, add 1.5L of ethanol with a mass fraction of 50%, heat and reflux twice, each time for 1.5h, Combine the extracts, concentrate under reduced pressure at 60°C until there is no alcohol smell, and then purify on a D101 macroporous resin column, collect the eluting fraction with a mass fraction of 60% ethanol, concentrate under reduced pressure to obtain 80 mL of concentrated solution, and then add 20 mL of butane Glycol, filtered, the extract of 100mL Chinese medicine composition is obtained, and its solid content is 9.8%, and pH value is 5.71.

[0022]

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PUM

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Abstract

The invention discloses an extract of a traditional Chinese medicine composite with an anti-allergy effect. The traditional Chinese medicine composite comprises the following traditional Chinese medicine components by weight percentage: 10-40% of cortex dictamni, 5-30% of lithospermum erythrorhizon, 5-30% of radix saposhnikoviae, 5-30% of Chinese angelica, 5-20% of radix polygonati officinalis, and 5-25% of liquorice. After the traditional Chinese medicine composite is subjected to heating and reflux extraction, an extracting solution is condensed and then passes through a macroporous resin column; elution is performed by an alcohol solution; an eluant is depressurized and condensed; dilution is performed by butanediol; and then the extract of the traditional Chinese medicine composite is obtained. The extract of the traditional Chinese medicine composite has good functions of restraining skin allergy and relieving skin itching, and can be applied to external skin agents such as cosmetics.

Description

[0001] technical field [0002] The invention relates to an extract of a traditional Chinese medicine composition with anti-allergic effect. The extract of the traditional Chinese medicine composition has good functions of inhibiting skin allergy and relieving skin itching, and can be applied to skin external preparations such as cosmetics. Background technique [0003] Skin allergy is a common form of allergy, according to surveys, about 20% of people will have skin allergies. Skin that is prone to skin allergies is also called sensitive skin. Various external factors lead to allergic reactions on the skin, and abnormal phenomena such as redness, itching, peeling and allergic dermatitis will appear. The incidence of skin allergies in our country is very high, especially in autumn and winter, when the skin is dry, many people will show skin allergy symptoms such as skin itching. [0004] The pathogenesis of skin allergies includes two major aspects: internal factors and ex...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K8/97A61P17/00A61P37/08A61Q19/00
Inventor 龚盛昭
Owner GUANGDONG IND TECHN COLLEGE
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