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Surface plasmon resonance imaging detection device and its light source

A surface plasmon and resonance imaging technology, applied in the field of detection, can solve the problem of high cost and achieve the effect of reducing cost

Active Publication Date: 2017-01-04
苏州普芯生命科学技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the cost of the SPR imaging detection device in the prior art is relatively high

Method used

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  • Surface plasmon resonance imaging detection device and its light source
  • Surface plasmon resonance imaging detection device and its light source
  • Surface plasmon resonance imaging detection device and its light source

Examples

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Embodiment Construction

[0041] Such as figure 1 As shown, the SPR imaging detection device in the prior art includes: a surface plasmon resonance microarray protein sensor, an incident arm, a reflection arm and a signal processing unit, wherein the surface plasmon resonance microarray protein sensor includes: a prism 025, a set The microarray chip 027 on the bottom surface of the prism 025 and the sample pool 029 placed under the microarray chip 027; the refractive index oil layer 026 is coated between the prism 025 and the microarray chip 027; One side of the array protein sensor includes a semiconductor laser 019, a collimator 021 with a built-in pinhole filter 020, a polarizer 022, an attenuator 023 and a rectangular diaphragm 024; The other side of the surface plasmon resonance microarray protein sensor includes a lens 030 and a CCD receiver 031 in turn; the signal processing unit includes a signal processing circuit 032 connected to the CCD receiver 031 and a computer 033 storing a signal proces...

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Abstract

The embodiment of the invention discloses a light source of an SPR (Surface Plasma Resonance) imaging detection device. The light source comprises a white LED for generating white emergent light, a collimator for collimating the emergent light of the white LED, a polarizer for adjusting the polarization direction of the collimated emergent light to TM polarization, an attenuator for adjusting the intensity of the emergent light of the polarizer, and a filter for filtering the emergent light of the attenuator. The technical scheme provided by the embodiment of the invention is that the white LED is used for generating white emergent light, and then the filter is used for filtering the emergent light of the white LED, so that the emergent light with single wavelength can be formed, and a semiconductor optical maser in the prior art can be replaced to generate the emergent light with single wavelength. As the cost of a high-power white LED is far less than that of a high-power semiconductor optical maser, the cost of the light source in the SPR imaging detection device is reduced, and further the cost of the SPR imaging detection device is reduced.

Description

technical field [0001] The invention relates to the technical field of detection, in particular to a light source of a surface plasmon resonance imaging detection device and a surface plasmon resonance imaging detection device including the light source. Background technique [0002] Surface Plasmon Resonance (SPR) sensor is a sensor that can detect subtle changes in the optical properties of the medium to be measured (such as medium thickness, refractive index, etc.), and its core component is a metal functional layer. When incident light with a certain incident angle, wavelength and transverse magnetic (TM) polarization direction passes through a coupler such as a prism, surface plasmon waves (Surface Plasmon) will be excited at the interface between the metal functional layer and the medium to be measured. Wave, referred to as SPW). When the excitation efficiency of the surface plasmon wave is the highest, the SPR phenomenon will occur, that is, the intensity of the refl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/41
Inventor 王丽红汪之又刘鸿朱劲松
Owner 苏州普芯生命科学技术有限公司
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