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Lotus leaf-based preparation for treating phlegm and blood stasis simultaneously and application thereof

A technology of Hedan and preparation, applied in the application field of medicine, can solve the problems of low content of active ingredients and the like

Active Publication Date: 2014-03-26
NANCHANG JISHUN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The object of the present invention is to provide a Hedan preparation that treats phlegm and blood stasis simultaneously and its application in the preparation of medicines for treating turbid phlegm and blood stasis at the same time, so as to solve the problem of low content of active ingredients in the existing preparations

Method used

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  • Lotus leaf-based preparation for treating phlegm and blood stasis simultaneously and application thereof
  • Lotus leaf-based preparation for treating phlegm and blood stasis simultaneously and application thereof
  • Lotus leaf-based preparation for treating phlegm and blood stasis simultaneously and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0093] 1. (1) After the lotus leaf is crushed, add ethanol which is 4 times the weight of the lotus leaf and has a mass fraction of 60%, adjust the pH to 12.0, reflux and extract twice at 75°C for 2 hours each time, and collect the extract for later use;

[0094] (2) Add the residue of the lotus leaf medicinal material obtained in (1) to 4 times the weight of the residue and 85% ethanol, adjust the pH to 3.0, and reflux extraction at 75°C for 3 times, each time for 2 hours, and collect and extract Liquid standby;

[0095] (3) Centrifuge and filter the supernatant of the extract in (1), reclaim ethanol by distillation under reduced pressure, adjust the pH to 7.0, then centrifuge and filter, and get the supernatant to prepare a 3 mg / mL solution, pump Into the AB-8 macroporous resin column for adsorption, the loading volume is 4BV, after gradient elution with pure water, 20% ethanol 2BV each, and elution with 70% ethanol, the eluate is collected, and the ethanol is recovered unde...

Embodiment 2

[0105] 320g of lotus leaf extract, 160g of salvia miltiorrhiza extract, 240g of hawthorn extract, 160g of salt psoralen extract and 4g of senna leaf extract prepared in the 1-5 steps of embodiment 1 are mixed, add sugar powder, starch, Low-substituted hydroxypropyl cellulose and other auxiliary materials are used in appropriate amounts to prepare 1000 g of granules.

Embodiment 3

[0107] Mix 160g of lotus leaf extract, 20g of salvia miltiorrhiza extract, 120g of hawthorn extract, 20g of salt psoralen extract, and 6g of senna leaf extract prepared in steps 1-5 of Example 1, add starch, low-substituted hydroxyl Appropriate amount of auxiliary materials such as propyl cellulose, made into granules, and packed into 1000 capsules.

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Abstract

The invention discloses a lotus leaf-based preparation for treating phlegm and blood stasis simultaneously. The pharmaceutical composition is prepared from the following traditional Chinese medicine extracts in parts by weight: 40-80 parts of lotus leaf extract, 10-20 parts of salvia miltiorrhiza extract, 30-60 parts of hawthorn extract, 10-20 parts of malaytea scurfpea fruit extract or salt scurfpea fruit extract, and 1-3 parts of senna extract. The invention further discloses application of the lotus leaf-based preparation in the preparation of medicines for treating phlegm turbidity and blood stasis simultaneously. The lotus leaf-based preparation disclosed by the invention has the activity in lowering blood lipid levels, and can be used for treating phlegm and blood stasis simultaneously and lowering the blood lipid levels.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine preparation in treating turbid phlegm and blood stasis, in particular to a He Dan preparation for treating phlegm and blood stasis simultaneously and its application in preparing a medicine for treating phlegm and blood stasis simultaneously. Background technique [0002] According to traditional Chinese medicine, phlegm turbidity and blood stasis are the pathological products of abnormal metabolism of water and grain in the body. Improper movement and transformation of the spleen leads to internal generation of turbid phlegm, internal stagnation of water vapor, coagulation of phlegm, and blockage of meridians. In recent years, in the clinical practice of chest pain, apoplexy, diabetes and other diseases, further understanding and attention have been paid to the co-morbidity of phlegm and blood stasis. , "phlegm and blood stasis stagnation" and so on are syndrome differentiatio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61P3/06
Inventor 何凯南曾英姿周万辉安少凯张丹赵磊陈武
Owner NANCHANG JISHUN PHARMA CO LTD
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