Biosensor Array Based on Ion Sensitive Field Effect Transistor

Abstract

The present invention relates to a biosensor array based on ion-sensitive field effect transistors, including row biosensors, column biosensors, row decoder circuits, column decoder circuits, and control logic circuits, the row biosensors and row decoder circuits The column biosensor is connected to the column decoder circuit, and the control logic circuit is coupled to the row decoder circuit and the column decoder circuit. The superior effect of the ion-sensitive field-effect transistor-based biosensor array of the present invention is that: the biosensor array greatly covers the detection area, and through the measurement of a large number of sensors inside the biosensor array, multiple targets can be detected simultaneously in real time and quickly , which greatly reduces the statistical error of the detection, thereby improving the accuracy and repeatability of the detection.

Description

technical field [0001] The invention belongs to the field of biosensors, in particular to a biosensor array based on ion-sensitive field effect transistors. Background technique [0002] Since the biosensor was proposed by Clark and Lyons in 1962, it has been deeply valued and widely used in fermentation technology, environmental monitoring, food engineering, clinical medicine, military and military medicine. The initial biosensors were mainly based on the development of biosensors made of enzyme electrodes. However, due to the high price and poor stability of enzyme preparations, the application of enzyme biosensors is limited to a certain extent. In recent years, with the continuous development of molecular biology and microbial immobilization technology, DNA sensors and microbial cell sensors have gradually become the mainstream of biosensor development. Microbial sensors can truly evaluate the biological effects of target substances in the environment. Relevant research...

AI Technical Summary

Problems solved by technology

[0007] The biosensors disclosed in the prior art have complex structures and poor practicability; while the biosensor arrays are all based on the arrangement and combination of existing biosensors, that is, the existing biosensor arrays have the same shortcomings as above. In order to solve the problems in the prior art, this Invention proposes a biosensor array based on ion-sensitive field-effect transistors

Images